ATE241635T1 - Neue potentiell fluorogene verbindungen - Google Patents
Neue potentiell fluorogene verbindungenInfo
- Publication number
- ATE241635T1 ATE241635T1 AT98105195T AT98105195T ATE241635T1 AT E241635 T1 ATE241635 T1 AT E241635T1 AT 98105195 T AT98105195 T AT 98105195T AT 98105195 T AT98105195 T AT 98105195T AT E241635 T1 ATE241635 T1 AT E241635T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- inositol
- organic
- formula
- inorganic base
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 150000007529 inorganic bases Chemical class 0.000 abstract 2
- 150000007530 organic bases Chemical class 0.000 abstract 2
- -1 4-methylumbelliferyl myo-inositol-1-phosphate Chemical compound 0.000 abstract 1
- 241000193403 Clostridium Species 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 241000186781 Listeria Species 0.000 abstract 1
- 102000006486 Phosphoinositide Phospholipase C Human genes 0.000 abstract 1
- 108010044302 Phosphoinositide phospholipase C Proteins 0.000 abstract 1
- 241000191940 Staphylococcus Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 244000052616 bacterial pathogen Species 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 238000003776 cleavage reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000007017 scission Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000001308 synthesis method Methods 0.000 abstract 1
- 238000010998 test method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/20—Coumarin derivatives
- C12Q2334/22—4-Methylumbelliferyl, i.e. beta-methylumbelliferone, 4MU
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/50—Indoles
- C12Q2334/52—5-Bromo-4-chloro-3-indolyl, i.e. BCI
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98105195A EP0949266B1 (de) | 1998-03-23 | 1998-03-23 | Neue potentiell fluorogene Verbindungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE241635T1 true ATE241635T1 (de) | 2003-06-15 |
Family
ID=8231636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98105195T ATE241635T1 (de) | 1998-03-23 | 1998-03-23 | Neue potentiell fluorogene verbindungen |
Country Status (8)
Country | Link |
---|---|
US (1) | US6416970B1 (de) |
EP (1) | EP0949266B1 (de) |
JP (1) | JP3581958B2 (de) |
AT (1) | ATE241635T1 (de) |
AU (1) | AU749667B2 (de) |
CA (1) | CA2323926C (de) |
DE (1) | DE69815060T2 (de) |
WO (1) | WO1999048899A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558917B2 (en) * | 1998-03-23 | 2003-05-06 | Biosynth Ag | Potentially fluorogenic compounds and plating media containing same |
ATE236176T1 (de) * | 2000-12-27 | 2003-04-15 | Biosynth Ag | Neue substrate zur detektion von mikrobiellen metaboliten |
KR100413829B1 (ko) * | 2001-03-23 | 2003-12-31 | 삼성전자주식회사 | 트렌치 격리 구조 및 그 형성 방법 |
EP1616025B1 (de) | 2003-04-17 | 2007-09-12 | The American National Red Cross | Fluoreszenzsubstrate zum nachweis von organophosphatase-enzymaktivität |
FR2935002B1 (fr) * | 2008-08-13 | 2014-09-05 | Biomerieux Sa | Milieu de culture permettant de differencier staphylococcus aureus des staphylococcus a coagulase negative |
US9322048B2 (en) * | 2009-09-18 | 2016-04-26 | Biomerieux, S.A. | Kit for identifying bacteria from the Bacillus cereus group |
US8501457B2 (en) * | 2010-08-30 | 2013-08-06 | Samsung Techwin Co., Ltd. | Enrichment of Listeria spp |
US11674165B2 (en) * | 2018-07-05 | 2023-06-13 | Merck Patent Gmbh | Enrichment of Listeria |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3772340A (en) * | 1972-05-02 | 1973-11-13 | Miles Lab | Bis(coumarinyl)phosphates |
US5364767A (en) | 1993-02-11 | 1994-11-15 | Research Organics, In. | Chromogenic compounds and methods of using same |
US6068988A (en) * | 1997-02-28 | 2000-05-30 | Biosynth Ag | Detection of microbial metabolites with a 3-indoxyl-myo-inositol-1-phosphate compound |
-
1998
- 1998-03-23 AT AT98105195T patent/ATE241635T1/de not_active IP Right Cessation
- 1998-03-23 DE DE69815060T patent/DE69815060T2/de not_active Expired - Lifetime
- 1998-03-23 EP EP98105195A patent/EP0949266B1/de not_active Expired - Lifetime
-
1999
- 1999-02-02 WO PCT/EP1999/000678 patent/WO1999048899A1/en active IP Right Grant
- 1999-02-02 JP JP2000537882A patent/JP3581958B2/ja not_active Expired - Fee Related
- 1999-02-02 CA CA002323926A patent/CA2323926C/en not_active Expired - Fee Related
- 1999-02-02 US US09/646,528 patent/US6416970B1/en not_active Expired - Lifetime
- 1999-02-02 AU AU25211/99A patent/AU749667B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
WO1999048899A1 (en) | 1999-09-30 |
JP3581958B2 (ja) | 2004-10-27 |
DE69815060D1 (de) | 2003-07-03 |
CA2323926C (en) | 2005-06-21 |
EP0949266A1 (de) | 1999-10-13 |
EP0949266B1 (de) | 2003-05-28 |
DE69815060T2 (de) | 2004-01-08 |
JP2002507619A (ja) | 2002-03-12 |
CA2323926A1 (en) | 1999-09-30 |
AU2521199A (en) | 1999-10-18 |
US6416970B1 (en) | 2002-07-09 |
AU749667B2 (en) | 2002-07-04 |
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Legal Events
Date | Code | Title | Description |
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UEP | Publication of translation of european patent specification |
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REN | Ceased due to non-payment of the annual fee |