ATE241011T1 - Serin-reiche peptidlinker - Google Patents
Serin-reiche peptidlinkerInfo
- Publication number
- ATE241011T1 ATE241011T1 AT92907232T AT92907232T ATE241011T1 AT E241011 T1 ATE241011 T1 AT E241011T1 AT 92907232 T AT92907232 T AT 92907232T AT 92907232 T AT92907232 T AT 92907232T AT E241011 T1 ATE241011 T1 AT E241011T1
- Authority
- AT
- Austria
- Prior art keywords
- serine
- peptide linkers
- ser
- rich peptide
- domains
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66222691A | 1991-02-27 | 1991-02-27 | |
PCT/US1992/001478 WO1992015682A1 (en) | 1991-02-27 | 1992-02-27 | Serine-rich peptide linkers |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE241011T1 true ATE241011T1 (de) | 2003-06-15 |
Family
ID=24656899
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92907232T ATE241011T1 (de) | 1991-02-27 | 1992-02-27 | Serin-reiche peptidlinker |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0573551B1 (de) |
JP (1) | JPH06508985A (de) |
AT (1) | ATE241011T1 (de) |
AU (1) | AU664030B2 (de) |
CA (1) | CA2100671C (de) |
DE (1) | DE69233068T2 (de) |
DK (1) | DK0573551T3 (de) |
ES (1) | ES2194838T3 (de) |
WO (1) | WO1992015682A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0393438B1 (de) * | 1989-04-21 | 2005-02-16 | Amgen Inc. | TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs |
US7264944B1 (en) | 1989-04-21 | 2007-09-04 | Amgen Inc. | TNF receptors, TNF binding proteins and DNAs coding for them |
US6143866A (en) * | 1989-07-18 | 2000-11-07 | Amgen, Inc. | Tumor necrosis factor (TNF) inhibitor and method for obtaining the same |
IL95031A (en) | 1989-07-18 | 2007-03-08 | Amgen Inc | A method of producing a recombinant human necrotic factor absorber |
US6027725A (en) * | 1991-11-25 | 2000-02-22 | Enzon, Inc. | Multivalent antigen-binding proteins |
EP0625200B1 (de) * | 1992-02-06 | 2005-05-11 | Chiron Corporation | Marker für krebs und biosynthetisches bindeprotein dafür |
AU5670194A (en) * | 1992-11-20 | 1994-06-22 | Enzon, Inc. | Linker for linked fusion polypeptides |
TW555765B (en) | 1996-07-09 | 2003-10-01 | Amgen Inc | Low molecular weight soluble tumor necrosis factor type-I and type-II proteins |
PT1095141E (pt) * | 1998-07-10 | 2006-07-31 | Scios Inc | Metodo para a producao de um peptido com um pi acima de 8 ou abaixo de 5 |
US9321832B2 (en) | 2002-06-28 | 2016-04-26 | Domantis Limited | Ligand |
CA2544532C (en) | 2003-11-28 | 2015-06-16 | Micromet Ag | Compositions comprising polypeptides |
US7235641B2 (en) | 2003-12-22 | 2007-06-26 | Micromet Ag | Bispecific antibodies |
CA2662226C (en) | 2006-09-10 | 2020-08-04 | Glycotope Gmbh | Fully human high yield production system for improved antibodies and proteins |
EP1920782A1 (de) | 2006-11-10 | 2008-05-14 | Glycotope Gmbh | Mikroorganismen oder deren Fraktionen fähig zur Aktivierung von Zelleimmunität gegen Kohlenhydrate |
ATE548052T1 (de) | 2008-01-17 | 2012-03-15 | Philogen Spa | Kombination aus einem anti-edb-fibronectin- antikörper-il-2-fusionsprotein und einem b-zellen bindenden molekül, b-zellen-vorläufern und/oder deren krebserregendem gegenspieler |
EP2116555A1 (de) | 2008-05-08 | 2009-11-11 | Bayer Schering Pharma Aktiengesellschaft | Verwendung eines spezifisch an ED-B Fibronectin bindenden radioaktiv markierten Moleküls bei einem Verfahren zur Behandlung von Hodgkin-Lymphom |
WO2010059315A1 (en) | 2008-11-18 | 2010-05-27 | Merrimack Pharmaceuticals, Inc. | Human serum albumin linkers and conjugates thereof |
WO2011110490A1 (en) | 2010-03-09 | 2011-09-15 | Bayer Pharma Aktiengesellschaft | Process for the production of radioactively labelled scfv antibody fragments, kits and compositions |
SG191153A1 (en) | 2010-12-23 | 2013-07-31 | Hoffmann La Roche | Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery |
CA2817448C (en) | 2010-12-23 | 2019-01-22 | F. Hoffmann-La Roche Ag | Binding agent |
WO2012085064A1 (en) | 2010-12-23 | 2012-06-28 | Roche Diagnostics Gmbh | Detection of a posttranslationally modified polypeptide by a bi-valent binding agent |
WO2012085069A2 (en) * | 2010-12-23 | 2012-06-28 | Roche Diagnostics Gmbh | Detection of a polypeptide dimer by a bivalent binding agent |
US9700610B2 (en) | 2011-08-22 | 2017-07-11 | Glycotope Gmbh | Microorganisms carrying a tumor antigen |
CN104039822A (zh) | 2011-09-06 | 2014-09-10 | 诺沃—诺迪斯克有限公司 | Glp-1衍生物 |
US20130344565A1 (en) * | 2012-06-21 | 2013-12-26 | Rapid Pathogen Screening, Inc. | Optimization of Expression and Purification of Recombinant Human MxA Protein in E. Coli |
WO2014036520A1 (en) | 2012-08-30 | 2014-03-06 | Merrimack Pharmaceuticals, Inc. | Combination therapies comprising anti-erbb3 agents |
US11472876B2 (en) | 2015-11-02 | 2022-10-18 | Bioatla, Inc. | Conditionally active polypeptides |
CA3100608A1 (en) | 2018-05-18 | 2019-11-21 | Daiichi Sankyo Co., Ltd. | Anti-muc1 antibody-drug conjugate |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US831967A (en) * | 1905-08-29 | 1906-09-25 | Eugenie Mearis | Table. |
DK0489116T3 (da) * | 1989-08-22 | 1994-05-02 | Immunex Corp | Fusionsproteiner omfattende GM-CSF og IL-3 |
EP0625200B1 (de) * | 1992-02-06 | 2005-05-11 | Chiron Corporation | Marker für krebs und biosynthetisches bindeprotein dafür |
-
1992
- 1992-02-27 AU AU14403/92A patent/AU664030B2/en not_active Expired
- 1992-02-27 WO PCT/US1992/001478 patent/WO1992015682A1/en active IP Right Grant
- 1992-02-27 AT AT92907232T patent/ATE241011T1/de active
- 1992-02-27 EP EP92907232A patent/EP0573551B1/de not_active Expired - Lifetime
- 1992-02-27 JP JP4507077A patent/JPH06508985A/ja active Pending
- 1992-02-27 CA CA002100671A patent/CA2100671C/en not_active Expired - Lifetime
- 1992-02-27 DK DK92907232T patent/DK0573551T3/da active
- 1992-02-27 ES ES92907232T patent/ES2194838T3/es not_active Expired - Lifetime
- 1992-02-27 DE DE69233068T patent/DE69233068T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0573551B1 (de) | 2003-05-21 |
ES2194838T3 (es) | 2003-12-01 |
CA2100671A1 (en) | 1992-08-28 |
EP0573551A4 (en) | 1994-06-08 |
JPH06508985A (ja) | 1994-10-13 |
AU664030B2 (en) | 1995-11-02 |
DE69233068D1 (de) | 2003-06-26 |
DK0573551T3 (da) | 2003-08-04 |
CA2100671C (en) | 1999-02-02 |
EP0573551A1 (de) | 1993-12-15 |
WO1992015682A1 (en) | 1992-09-17 |
AU1440392A (en) | 1992-10-06 |
DE69233068T2 (de) | 2004-01-22 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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