ATE240301T1 - Verfahren zur herstellung von 4,6- dichloropyrimidin - Google Patents

Verfahren zur herstellung von 4,6- dichloropyrimidin

Info

Publication number: ATE240301T1
Authority: AT; Austria
Prior art keywords: dichloropyrimidine; dihydroxypyrimidine; phosgene; phenyl; alkyl
Prior art date: 1994-04-26

Application number

AT95912362T

Other languages

English (en)

Inventor

Martin Charles Bowden

Stephen Martin Brown

John David Jones

Original Assignee

Syngenta Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-26

Filing date

1995-03-27

Publication date

2003-05-15

1995-03-27 Application filed by Syngenta Ltd filed Critical Syngenta Ltd

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE240301T1 publication Critical patent/ATE240301T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Physical Or Chemical Processes And Apparatus (AREA)

AT95912362T 1994-04-26 1995-03-27 Verfahren zur herstellung von 4,6- dichloropyrimidin ATE240301T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9408270A GB9408270D0 (en)	1994-04-26	1994-04-26	Chemical process
PCT/GB1995/000676 WO1995029166A1 (en)	1994-04-26	1995-03-27	Process for the preparation of 4,6-dichloropyrimidine

Publications (1)

Publication Number	Publication Date
ATE240301T1 true ATE240301T1 (de)	2003-05-15

Family

ID=10754155

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT95912362T ATE240301T1 (de)	1994-04-26	1995-03-27	Verfahren zur herstellung von 4,6- dichloropyrimidin
AT02022777T ATE308526T1 (de)	1994-04-26	1995-03-27	Verfahren zu herstellung von 4,6- dichloropyrimidine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02022777T ATE308526T1 (de)	1994-04-26	1995-03-27	Verfahren zu herstellung von 4,6- dichloropyrimidine

Country Status (20)

Country	Link
US (1)	US5750694A (de)
EP (2)	EP1273574B1 (de)
JP (1)	JP3688295B2 (de)
CN (2)	CN1255388C (de)
AT (2)	ATE240301T1 (de)
BR (1)	BR9507481A (de)
CA (1)	CA2182522C (de)
CZ (1)	CZ289265B6 (de)
DE (2)	DE69530765T2 (de)
DK (2)	DK0757678T3 (de)
ES (2)	ES2199983T3 (de)
GB (1)	GB9408270D0 (de)
HU (1)	HU220374B (de)
IL (1)	IL113143A (de)
PL (1)	PL182718B1 (de)
RO (1)	RO117450B1 (de)
RU (1)	RU2156240C2 (de)
SK (1)	SK137196A3 (de)
TW (1)	TW388759B (de)
WO (1)	WO1995029166A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT402818B (de) *	1995-06-02	1997-09-25	Chemie Linz Gmbh	Verfahren zur herstellung von reinem 4,6-dichlorpyrimidin
DE19531299A1 (de) *	1995-08-25	1997-02-27	Bayer Ag	Verfahren zur Herstellung von 4,6-Dichlorpyrimidinen
US6160117A (en) *	1997-11-06	2000-12-12	Zeneca Limited	Chemical process
WO2000046212A1 (en) *	1999-02-05	2000-08-10	Syngenta Participations Ag	Method of producing substituted pyrimidine derivatives
DE19929350A1 (de)	1999-06-26	2000-12-28	Bayer Ag	Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Säurechloriden
DE19929353A1 (de)	1999-06-26	2000-12-28	Bayer Ag	Verfahren zur Herstellung von 4,6-Dichlorpyrimidin
DE19935322A1 (de)	1999-07-28	2001-02-01	Bayer Ag	Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Phosgen
DE19938500A1 (de)	1999-08-13	2001-02-15	Bayer Ag	Verfahren zur Herstellung von 4,6-Dichlorpyrimidin mit Schwefel- und Phosphorverbindungen
US20020042514A1 (en) *	2000-06-26	2002-04-11	Doyle Timothy John	Synthesis of chlorinated pyrimidines
US6608199B2 (en)	2000-07-07	2003-08-19	Syngenta Limited	Synthesis of chlorinated pyrimidines
US6982331B2 (en) *	2001-06-08	2006-01-03	Syngenta Crop Protection, Inc.	Synthesis of chlorinated pyrimidines
DE10226220A1 (de) *	2002-06-13	2003-12-24	Bayer Cropscience Ag	Verfahren zur Herstellung von 4,6-Dichlor-5-fluorpyrimidin
CN1321986C (zh) *	2005-06-20	2007-06-20	江苏省激素研究所有限公司	制备4,6－二氯嘧啶的方法
US10018782B2 (en)	2015-05-28	2018-07-10	Corning Optical Communications LLC	Optical fiber stripping methods and apparatus
CN105859636A (zh) *	2016-05-13	2016-08-17	安徽广信农化股份有限公司	一种以4,6-二羟基嘧啶为中间体的4,6-二氯嘧啶的合成方法
CN105906570A (zh) *	2016-05-13	2016-08-31	安徽广信农化股份有限公司	一种4,6-二氯嘧啶的合成工艺
CN105859637A (zh) *	2016-05-13	2016-08-17	安徽广信农化股份有限公司	4,6-二氯嘧啶的合成及工艺优化
CN106187913A (zh) *	2016-07-19	2016-12-07	安徽广信农化股份有限公司	一种改进后的4,6‑二氯嘧啶的生产工艺
CN106045917A (zh) *	2016-07-19	2016-10-26	安徽广信农化股份有限公司	一步法制备4,6‑二氯嘧啶的合成工艺
CN108178748B (zh) *	2018-01-19	2021-04-06	和记黄埔医药（上海）有限公司	4,6-二氯嘧啶-5-甲腈的合成方法
CN109516958B (zh) *	2018-12-26	2020-12-08	杭州布朗生物医药科技有限公司	一种2,4-二氯嘧啶及其衍生物的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1310810A (fr) *	1960-11-26	1962-11-30	Basf Ag	Procédé pour la production de composés chlorés hétérocycliques
DE3220105A1 (de) *	1982-05-28	1983-12-01	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung in (alpha)-stellung chlorierten stickstoff-heterocyclen
DE3228712A1 (de) *	1982-07-31	1984-02-02	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von 2,4,5,6-tetrachlorpyrimidin
DE3431698A1 (de) *	1984-08-29	1986-03-13	Bayer Ag, 5090 Leverkusen	5,5-dichlor-4,5-dihydro-6-hydroxy-2-trichlormethyl-pyrimidin-4-on, ein verfahren zu seiner herstellung und seine verwendung
DE3441789A1 (de) *	1984-11-15	1986-05-15	Bayer Ag, 5090 Leverkusen	5,6-dichlor-4-hydroxy-2-trichlormethylpyrimidin
DE3441935A1 (de) *	1984-11-16	1986-05-28	Bayer Ag, 5090 Leverkusen	Verfahren zur herstellung von 2,4-dihydroxypyrimidinen
GB8916698D0 (en) *	1989-07-21	1989-09-06	Beecham Group Plc	Novel process
DE4222518A1 (de) *	1992-07-09	1994-01-13	Bayer Ag	Verfahren zur Hertellung von 5-(Trifluormethyl)-uracil und die neuen Verbindungen 2,4-Dichlor-5-trichlormethyl-pyrimidin und 2,4-Difluor-5-trifluormethyl-pyrimidin
GB9220585D0 (en) *	1992-09-30	1992-11-11	Smithkline Beecham Plc	Pharmaceuticals
CN1082031A (zh) *	1993-05-20	1994-02-16	郑州市孝义制药厂	磺胺间甲氧嘧啶的制备方法
DE4408404A1 (de) *	1994-03-12	1995-09-14	Huels Chemische Werke Ag	Verfahren zur Herstellung von Chlorpyrimidinen

1994
- 1994-04-26 GB GB9408270A patent/GB9408270D0/en active Pending
1995
- 1995-03-27 AT AT95912362T patent/ATE240301T1/de active
- 1995-03-27 PL PL95317019A patent/PL182718B1/pl not_active IP Right Cessation
- 1995-03-27 RU RU96122489/04A patent/RU2156240C2/ru not_active IP Right Cessation
- 1995-03-27 EP EP02022777A patent/EP1273574B1/de not_active Expired - Lifetime
- 1995-03-27 CN CN200310120681.7A patent/CN1255388C/zh not_active Expired - Lifetime
- 1995-03-27 DK DK95912362T patent/DK0757678T3/da active
- 1995-03-27 CZ CZ19963126A patent/CZ289265B6/cs not_active IP Right Cessation
- 1995-03-27 US US08/669,568 patent/US5750694A/en not_active Expired - Lifetime
- 1995-03-27 JP JP52742695A patent/JP3688295B2/ja not_active Expired - Fee Related
- 1995-03-27 BR BR9507481A patent/BR9507481A/pt not_active Application Discontinuation
- 1995-03-27 IL IL11314395A patent/IL113143A/en not_active IP Right Cessation
- 1995-03-27 DE DE69530765T patent/DE69530765T2/de not_active Expired - Lifetime
- 1995-03-27 HU HU9602912A patent/HU220374B/hu unknown
- 1995-03-27 EP EP95912362A patent/EP0757678B1/de not_active Expired - Lifetime
- 1995-03-27 ES ES95912362T patent/ES2199983T3/es not_active Expired - Lifetime
- 1995-03-27 AT AT02022777T patent/ATE308526T1/de active
- 1995-03-27 ES ES02022777T patent/ES2251555T3/es not_active Expired - Lifetime
- 1995-03-27 DK DK02022777T patent/DK1273574T3/da active
- 1995-03-27 CA CA002182522A patent/CA2182522C/en not_active Expired - Lifetime
- 1995-03-27 SK SK1371-96A patent/SK137196A3/sk unknown
- 1995-03-27 RO RO96-02019A patent/RO117450B1/ro unknown
- 1995-03-27 DE DE69534576T patent/DE69534576T2/de not_active Expired - Lifetime
- 1995-03-27 WO PCT/GB1995/000676 patent/WO1995029166A1/en active IP Right Grant
- 1995-03-27 CN CNB951927639A patent/CN1140512C/zh not_active Expired - Lifetime
- 1995-03-30 TW TW084103063A patent/TW388759B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
CN1255388C (zh)	2006-05-10
DE69530765T2 (de)	2004-03-18
US5750694A (en)	1998-05-12
HU220374B (hu)	2002-01-28
JPH09512263A (ja)	1997-12-09
TW388759B (en)	2000-05-01
EP0757678A1 (de)	1997-02-12
CN1528751A (zh)	2004-09-15
HU9602912D0 (en)	1996-12-30
CZ289265B6 (cs)	2001-12-12
ES2199983T3 (es)	2004-03-01
CN1140512C (zh)	2004-03-03
EP1273574A1 (de)	2003-01-08
EP0757678B1 (de)	2003-05-14
PL182718B1 (pl)	2002-02-28
IL113143A (en)	1998-09-24
WO1995029166A1 (en)	1995-11-02
DE69534576T2 (de)	2006-06-08
ES2251555T3 (es)	2006-05-01
CN1146766A (zh)	1997-04-02
SK137196A3 (en)	1997-05-07
IL113143A0 (en)	1995-08-31
DK1273574T3 (da)	2006-02-13
CA2182522A1 (en)	1995-11-02
DK0757678T3 (da)	2003-07-21
ATE308526T1 (de)	2005-11-15
JP3688295B2 (ja)	2005-08-24
DE69530765D1 (de)	2003-06-18
EP1273574B1 (de)	2005-11-02
RU2156240C2 (ru)	2000-09-20
BR9507481A (pt)	1997-08-12
GB9408270D0 (en)	1994-06-15
CA2182522C (en)	2006-07-11
RO117450B1 (ro)	2002-03-29
DE69534576D1 (de)	2005-12-08
PL317019A1 (en)	1997-03-03
CZ312696A3 (en)	1997-01-15
HUT74713A (en)	1997-02-28

Legal Events

Date

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2003-12-15

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Publication of translation of european patent specification

Ref document number: 0757678

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Publication	Publication Date	Title
ATE240301T1 (de)	2003-05-15	Verfahren zur herstellung von 4,6- dichloropyrimidin
ATE145891T1 (de)	1996-12-15	Verfahren zur herstellung von alkoxyiminoacetamid-derivaten und ein zwischenproduckt dafür
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RU96122489A (ru)	1999-01-27	Способ получения 4,6-дихлорпиримидина
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