ATE239003T1 - Dibenzothiophene derivate und ihre verwendung - Google Patents
Dibenzothiophene derivate und ihre verwendungInfo
- Publication number
- ATE239003T1 ATE239003T1 AT99930662T AT99930662T ATE239003T1 AT E239003 T1 ATE239003 T1 AT E239003T1 AT 99930662 T AT99930662 T AT 99930662T AT 99930662 T AT99930662 T AT 99930662T AT E239003 T1 ATE239003 T1 AT E239003T1
- Authority
- AT
- Austria
- Prior art keywords
- dicationic
- formula
- methods
- effective amount
- therapeutically effective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9727398P | 1998-08-20 | 1998-08-20 | |
PCT/US1999/014313 WO2000010990A2 (en) | 1998-08-20 | 1999-06-24 | Dicationic dibenzofuran and dibenzothiophene compounds and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE239003T1 true ATE239003T1 (de) | 2003-05-15 |
Family
ID=22262567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99930662T ATE239003T1 (de) | 1998-08-20 | 1999-06-24 | Dibenzothiophene derivate und ihre verwendung |
Country Status (9)
Country | Link |
---|---|
US (1) | US6172104B1 (de) |
EP (1) | EP1105381B1 (de) |
JP (1) | JP2003523927A (de) |
AT (1) | ATE239003T1 (de) |
AU (1) | AU758563B2 (de) |
CA (1) | CA2340912C (de) |
DE (1) | DE69907476T2 (de) |
ES (1) | ES2198139T3 (de) |
WO (1) | WO2000010990A2 (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2784678B1 (fr) * | 1998-09-23 | 2002-11-29 | Sod Conseils Rech Applic | Nouveaux derives de n-(iminomethyl)amines, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
US6569853B1 (en) * | 2000-11-06 | 2003-05-27 | Combinatorx, Incorporated | Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders |
GB2380192B8 (en) * | 2001-02-09 | 2005-09-14 | Sumitomo Chemical Co | Phenylacetylene compounds liquid crystal compositions polymers optically anisotropic products & optical & liquid crystal elements derived therefrom |
JP2002255960A (ja) * | 2001-02-27 | 2002-09-11 | Sumitomo Chem Co Ltd | ジベンゾチオフェン化合物、中間体およびその製造方法 |
EP1470119A4 (de) * | 2001-06-13 | 2005-10-19 | Genesoft Pharmaceuticals Inc | Benzothiophenverbindungen mit antiinfektiver wirkung |
WO2003017994A1 (en) * | 2001-08-31 | 2003-03-06 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
SG124249A1 (en) * | 2001-12-07 | 2006-08-30 | Sumitomo Chemical Co | New polymer and polymer light-emitting device using the same |
JP4957669B2 (ja) * | 2002-03-15 | 2012-06-20 | 住友化学株式会社 | 高分子化合物およびそれを用いた高分子発光素子 |
DE60326735D1 (de) | 2002-08-02 | 2009-04-30 | Genesoft Pharmaceuticals Inc | Biaryl-verbindungen mit antiinfektiver wirkung |
US7265129B2 (en) * | 2002-10-25 | 2007-09-04 | Genesoft Pharmaceuticals, Inc. | Anti-infective biaryl compounds |
JP2006509027A (ja) | 2002-12-10 | 2006-03-16 | オーシェント ファーマシューティカルズ コーポレーション | (ピロールカルボキサミド)−(ベンズアミド)−(イミダゾールカルボキサミド)モチーフを有する抗菌化合物 |
US20050054708A1 (en) * | 2003-07-28 | 2005-03-10 | Nichols Matthew James | Combinations of drugs for the treatment of neoplasms |
WO2005020913A2 (en) * | 2003-08-25 | 2005-03-10 | Combinatorx, Incorporated | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms |
US20050158320A1 (en) * | 2003-11-12 | 2005-07-21 | Nichols M. J. | Combinations for the treatment of proliferative diseases |
US20050100508A1 (en) * | 2003-11-12 | 2005-05-12 | Nichols M. J. | Methods for identifying drug combinations for the treatment of proliferative diseases |
EP1689705A4 (de) * | 2003-11-24 | 2007-08-29 | Univ North Carolina | Dikationische antiprotozoenmittel mit kondensiertem ring und prodrugs davon |
US7262223B2 (en) * | 2004-01-23 | 2007-08-28 | Neurochem (International) Limited | Amidine derivatives for treating amyloidosis |
US7365193B2 (en) | 2004-02-04 | 2008-04-29 | Abbott Laboratories | Amino-substituted tricyclic derivatives and methods of use |
US7994225B2 (en) * | 2004-03-17 | 2011-08-09 | Rempex Pharmaceuticals, Inc. | Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections |
WO2005089738A2 (en) * | 2004-03-17 | 2005-09-29 | Mpex Pharmaceuticals, Inc. | Use and administration of bacterial efflux pump inhibitors |
DE102004031656A1 (de) * | 2004-06-30 | 2006-01-19 | Merck Patent Gmbh | Tetrahydrochinoline |
GB0619325D0 (en) * | 2006-09-30 | 2006-11-08 | Univ Strathclyde | New compounds |
US20090092574A1 (en) | 2006-12-29 | 2009-04-09 | Scott Richard W | Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof |
DE102007013855A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydrochinoline |
DE102007013854A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Tetrahydrochinoline |
DE102007013856A1 (de) | 2007-03-20 | 2008-09-25 | Merck Patent Gmbh | Substituierte Tetrahydropyrrolochinoline |
US8796275B2 (en) * | 2008-07-28 | 2014-08-05 | The Trustees Of The University Of Pennsylvania | Anti-malarial compounds |
US8278309B2 (en) * | 2008-10-27 | 2012-10-02 | Polymedix, Inc. | Synthetic mimetics of host defense and uses thereof |
WO2011084970A1 (en) * | 2010-01-07 | 2011-07-14 | Polymedix Inc. | Anti-heparin compounds |
JP5833745B2 (ja) | 2011-05-16 | 2015-12-16 | セルシューティクス・コーポレーション | 粘膜炎の治療に使用するための化合物 |
US11771694B2 (en) | 2020-06-05 | 2023-10-03 | Innovation Pharmaceuticals Inc. | Arylamide compounds for treatment and prevention of viral infections |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2500734A (en) * | 1946-06-13 | 1950-03-14 | Gen Electric | Process of preparing 2-ethyldibenzofuran |
GB932813A (en) * | 1960-12-01 | 1963-07-31 | Monsanto Chemicals | New heterocyclic chemical compounds |
GB951797A (en) * | 1960-12-20 | 1964-03-11 | Monsanto Chemicals | Heterocyclic compounds |
US4362883A (en) * | 1981-10-28 | 1982-12-07 | The Halcon Sd Group, Inc. | Preparation of dibenzofuran |
AU626033B2 (en) | 1988-10-25 | 1992-07-23 | Government Of The United States Of America, As Represented By The Secretary Of The Army, The | Methods for the treatment and prophylaxis of pneumocystis carinii pneumonia and other diseases and compounds and formulations for use in said methods |
IL115875A (en) | 1994-11-14 | 2000-12-06 | Univ Georgia State Res Found | Methods of inhibiting pneumocystis carinii pneumonia giardia lamblia and cryptosporidium parvum in an animal subject and compounds useful therefor |
ES2211958T3 (es) | 1995-06-07 | 2004-07-16 | The University Of North Carolina At Chapel Hill | Carbazoles para tratar infecciones microbianas. |
US5668166A (en) * | 1995-06-07 | 1997-09-16 | Georgia State University Research Foundation, Inc. | Methods of inhibiting pneumocystis carinii pneumonia and compounds useful therefor |
US5723495A (en) * | 1995-11-16 | 1998-03-03 | The University Of North Carolina At Chapel Hill | Benzamidoxime prodrugs as antipneumocystic agents |
-
1999
- 1999-06-24 WO PCT/US1999/014313 patent/WO2000010990A2/en active IP Right Grant
- 1999-06-24 EP EP99930662A patent/EP1105381B1/de not_active Expired - Lifetime
- 1999-06-24 JP JP2000566263A patent/JP2003523927A/ja active Pending
- 1999-06-24 DE DE69907476T patent/DE69907476T2/de not_active Expired - Fee Related
- 1999-06-24 AU AU47152/99A patent/AU758563B2/en not_active Ceased
- 1999-06-24 ES ES99930662T patent/ES2198139T3/es not_active Expired - Lifetime
- 1999-06-24 CA CA002340912A patent/CA2340912C/en not_active Expired - Fee Related
- 1999-06-24 AT AT99930662T patent/ATE239003T1/de not_active IP Right Cessation
- 1999-06-24 US US09/344,143 patent/US6172104B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU758563B2 (en) | 2003-03-27 |
CA2340912C (en) | 2008-11-18 |
ES2198139T3 (es) | 2004-01-16 |
DE69907476T2 (de) | 2004-04-15 |
EP1105381A1 (de) | 2001-06-13 |
WO2000010990A2 (en) | 2000-03-02 |
EP1105381B1 (de) | 2003-05-02 |
DE69907476D1 (de) | 2003-06-05 |
AU4715299A (en) | 2000-03-14 |
CA2340912A1 (en) | 2000-03-02 |
JP2003523927A (ja) | 2003-08-12 |
US6172104B1 (en) | 2001-01-09 |
WO2000010990A3 (en) | 2003-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |