ATE236401T1 - Surrogate für bindemoleküle und verbesserte referenzpanele - Google Patents
Surrogate für bindemoleküle und verbesserte referenzpaneleInfo
- Publication number
- ATE236401T1 ATE236401T1 AT95906754T AT95906754T ATE236401T1 AT E236401 T1 ATE236401 T1 AT E236401T1 AT 95906754 T AT95906754 T AT 95906754T AT 95906754 T AT95906754 T AT 95906754T AT E236401 T1 ATE236401 T1 AT E236401T1
- Authority
- AT
- Austria
- Prior art keywords
- reactivity
- panels
- receptor
- panel
- members
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Laminated Bodies (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Forklifts And Lifting Vehicles (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/177,673 US5587293A (en) | 1994-01-06 | 1994-01-06 | Method to identify binding partners |
US08/308,813 US5798275A (en) | 1994-01-06 | 1994-09-19 | Profiling reference panel enriched by non-IG proteins |
PCT/US1995/000081 WO1995018969A1 (en) | 1994-01-06 | 1995-01-05 | Surrogates for targets and improved reference panels |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE236401T1 true ATE236401T1 (de) | 2003-04-15 |
Family
ID=26873529
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02009879T ATE359509T1 (de) | 1994-01-06 | 1995-01-05 | Ersatz für zielobjekte und verbesserten referenzplatten |
AT95906754T ATE236401T1 (de) | 1994-01-06 | 1995-01-05 | Surrogate für bindemoleküle und verbesserte referenzpanele |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02009879T ATE359509T1 (de) | 1994-01-06 | 1995-01-05 | Ersatz für zielobjekte und verbesserten referenzplatten |
Country Status (11)
Country | Link |
---|---|
US (1) | US5741653A (de) |
EP (1) | EP0738390B1 (de) |
JP (1) | JPH09507300A (de) |
AT (2) | ATE359509T1 (de) |
AU (1) | AU700497B2 (de) |
CA (1) | CA2178096C (de) |
DE (2) | DE69535463T2 (de) |
DK (2) | DK1235072T3 (de) |
ES (2) | ES2196056T3 (de) |
PT (1) | PT738390E (de) |
WO (1) | WO1995018969A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1394497A (en) | 1996-01-17 | 1997-08-11 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
US6054286A (en) * | 1996-06-18 | 2000-04-25 | Telik, Inc. | Methods to identify immunomodulators using cognate interaction of PKC-theta |
WO1998029744A2 (en) * | 1997-01-03 | 1998-07-09 | Telik, Inc. | Method to classify gene products |
CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
JP2002514571A (ja) | 1997-11-12 | 2002-05-21 | 3−ディメンショナル ファーマシューティカルズ, インコーポレイテッド | ゲノムアプローチを使用して同定されるタンパク質を機能的に分類するためのハイスループット方法 |
JP2002508507A (ja) * | 1997-12-18 | 2002-03-19 | セプラコア インコーポレーテッド | 新規な生物学的標的および創薬リード構造体の同時同定方法 |
US6410584B1 (en) | 1998-01-14 | 2002-06-25 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells with indole derivatives |
JP2002522750A (ja) | 1998-08-05 | 2002-07-23 | ユニバーシティ・オブ・ピッツバーグ | シトクロムp450媒介反応における有機化合物の反応性のモデル化 |
US6625547B1 (en) | 1998-08-05 | 2003-09-23 | Washington State University Research Foundation | Relative rates of cytochrome p450 metabolism |
CA2339817A1 (en) * | 1998-08-12 | 2000-02-24 | Zycos Inc. | Profiling and cataloging expressed protein tags |
US20040224338A1 (en) * | 1998-08-12 | 2004-11-11 | Zycos Inc., A Delaware Corporation | Profiling and cataloging expressed protein tags |
US6200771B1 (en) | 1998-10-15 | 2001-03-13 | Cell Pathways, Inc. | Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia |
US6569631B1 (en) | 1998-11-12 | 2003-05-27 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes |
US6133271A (en) * | 1998-11-19 | 2000-10-17 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives |
US6187779B1 (en) | 1998-11-20 | 2001-02-13 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives |
US6369092B1 (en) | 1998-11-23 | 2002-04-09 | Cell Pathways, Inc. | Method for treating neoplasia by exposure to substituted benzimidazole derivatives |
US6486155B1 (en) | 1998-11-24 | 2002-11-26 | Cell Pathways Inc | Method of inhibiting neoplastic cells with isoquinoline derivatives |
US6077842A (en) * | 1998-11-24 | 2000-06-20 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives |
US6034099A (en) * | 1998-11-24 | 2000-03-07 | Cell Pathways, Inc. | Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones |
US6875575B1 (en) | 1998-11-25 | 2005-04-05 | Osi Pharmaceuticals, Inc. | Diagnostic methods for neoplasia |
US6025394A (en) | 1999-01-29 | 2000-02-15 | Cell Pathways, Inc. | Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols |
US6020379A (en) * | 1999-02-19 | 2000-02-01 | Cell Pathways, Inc. | Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia |
EP3712897A1 (de) * | 2019-03-22 | 2020-09-23 | Tata Consultancy Services Limited | Automatisierte vorhersage der biologischen reaktion von chemischen verbindungen auf der basis chemischer informationen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ226552A (en) * | 1987-10-13 | 1991-04-26 | Terrapin Tech Inc | Method of selection of antibodies for use as immunodiagnostic reagents |
US4963263A (en) * | 1988-03-24 | 1990-10-16 | Terrapin Technologies, Inc. | Method of identity analyte-binding peptides |
US5338659A (en) * | 1991-04-02 | 1994-08-16 | Terrapin Technologies, Inc. | Method for determining analyte concentration by cross-reactivity profiling |
US5217869A (en) * | 1987-10-13 | 1993-06-08 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
US5133866A (en) * | 1988-03-24 | 1992-07-28 | Terrapin Technologies, Inc. | Method to identify analyte-bending ligands |
US5300425A (en) * | 1987-10-13 | 1994-04-05 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
US5340474A (en) * | 1988-03-24 | 1994-08-23 | Terrapin Technologies, Inc. | Panels of analyte-binding ligands |
EP0557276A1 (de) * | 1989-12-29 | 1993-09-01 | University Technologies International Inc. (Uti) | Verfahren zur modellierung von tertiärstrukturen von biologisch aktiven liganden einschliesslich ihrer agonisten und antagonisten und neue synthetische antagonisten auf angiotensinbasis |
JPH06502723A (ja) * | 1990-11-09 | 1994-03-24 | ヴェリジェン,インコーポレーテッド | 抗体を検出する分析系の感度及び/又は特異性の決定方法 |
-
1995
- 1995-01-05 DE DE69535463T patent/DE69535463T2/de not_active Expired - Fee Related
- 1995-01-05 EP EP95906754A patent/EP0738390B1/de not_active Expired - Lifetime
- 1995-01-05 ES ES95906754T patent/ES2196056T3/es not_active Expired - Lifetime
- 1995-01-05 AT AT02009879T patent/ATE359509T1/de not_active IP Right Cessation
- 1995-01-05 AU AU15221/95A patent/AU700497B2/en not_active Ceased
- 1995-01-05 AT AT95906754T patent/ATE236401T1/de not_active IP Right Cessation
- 1995-01-05 JP JP7518574A patent/JPH09507300A/ja active Pending
- 1995-01-05 CA CA002178096A patent/CA2178096C/en not_active Expired - Fee Related
- 1995-01-05 DK DK02009879T patent/DK1235072T3/da active
- 1995-01-05 ES ES02009879T patent/ES2284743T3/es not_active Expired - Lifetime
- 1995-01-05 DE DE69530179T patent/DE69530179T2/de not_active Expired - Fee Related
- 1995-01-05 WO PCT/US1995/000081 patent/WO1995018969A1/en active IP Right Grant
- 1995-01-05 PT PT95906754T patent/PT738390E/pt unknown
- 1995-01-05 DK DK95906754T patent/DK0738390T3/da active
-
1996
- 1996-03-26 US US08/622,693 patent/US5741653A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0738390B1 (de) | 2003-04-02 |
PT738390E (pt) | 2003-07-31 |
DE69530179D1 (de) | 2003-05-08 |
DE69530179T2 (de) | 2004-04-08 |
DE69535463D1 (de) | 2007-05-24 |
JPH09507300A (ja) | 1997-07-22 |
DK1235072T3 (da) | 2007-07-16 |
US5741653A (en) | 1998-04-21 |
EP0738390A1 (de) | 1996-10-23 |
ES2284743T3 (es) | 2007-11-16 |
CA2178096C (en) | 2004-03-09 |
CA2178096A1 (en) | 1995-07-13 |
ES2196056T3 (es) | 2003-12-16 |
DK0738390T3 (da) | 2003-07-21 |
WO1995018969A1 (en) | 1995-07-13 |
AU1522195A (en) | 1995-08-01 |
DE69535463T2 (de) | 2008-01-03 |
AU700497B2 (en) | 1999-01-07 |
ATE359509T1 (de) | 2007-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0738390 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |