ATE234626T1 - Verwendung von langkettigen n-alkyl derivaten von deoxynojirimycin mit glucocerebrosidase enzyme zur herstellung eines medikaments zur behandlung von mit glykolipiden akkumulation zusammenhängenden krankheiten - Google Patents

Verwendung von langkettigen n-alkyl derivaten von deoxynojirimycin mit glucocerebrosidase enzyme zur herstellung eines medikaments zur behandlung von mit glykolipiden akkumulation zusammenhängenden krankheiten

Info

Publication number
ATE234626T1
ATE234626T1 AT00946807T AT00946807T ATE234626T1 AT E234626 T1 ATE234626 T1 AT E234626T1 AT 00946807 T AT00946807 T AT 00946807T AT 00946807 T AT00946807 T AT 00946807T AT E234626 T1 ATE234626 T1 AT E234626T1
Authority
AT
Austria
Prior art keywords
deoxynojirimycin
treatment
medication
producing
long chain
Prior art date
Application number
AT00946807T
Other languages
English (en)
Inventor
Gary S Jacob
Raymond A Dwek
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE234626T1 publication Critical patent/ATE234626T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT00946807T 1999-07-26 2000-07-24 Verwendung von langkettigen n-alkyl derivaten von deoxynojirimycin mit glucocerebrosidase enzyme zur herstellung eines medikaments zur behandlung von mit glykolipiden akkumulation zusammenhängenden krankheiten ATE234626T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14556899P 1999-07-26 1999-07-26
PCT/US2000/016340 WO2001007078A1 (en) 1999-07-26 2000-07-24 Use of long-chain n-alkyl derivates of deoxynojirimycin and a glucocerebrosidase enzyme for the manufacture of medicament for the treatment of glycolipid storage diseases

Publications (1)

Publication Number Publication Date
ATE234626T1 true ATE234626T1 (de) 2003-04-15

Family

ID=22513679

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00946807T ATE234626T1 (de) 1999-07-26 2000-07-24 Verwendung von langkettigen n-alkyl derivaten von deoxynojirimycin mit glucocerebrosidase enzyme zur herstellung eines medikaments zur behandlung von mit glykolipiden akkumulation zusammenhängenden krankheiten

Country Status (8)

Country Link
US (2) US6495570B2 (de)
EP (1) EP1196190B1 (de)
JP (1) JP2003505430A (de)
AT (1) ATE234626T1 (de)
AU (1) AU6050600A (de)
CA (1) CA2378776A1 (de)
DE (1) DE60001745T2 (de)
WO (1) WO2001007078A1 (de)

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ES2393919T3 (es) * 2002-07-17 2013-01-02 Actelion Pharmaceuticals Ltd. Derivados de PIPERIDINETRIOL como inhibidores de GLUCOSILCERAMIDA SINTASA
WO2004037373A2 (en) * 2002-10-21 2004-05-06 The Scripps Research Institute CHEMICAL CHAPERONES AND THEIR EFFECT UPON THE CELLULAR ACTIVITY OF β-GLUCOSIDASE
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GB0313678D0 (en) * 2003-06-13 2003-07-16 Oxford Glycosciences Uk Ltd Novel compounds
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AU2004289328B2 (en) * 2003-11-12 2011-05-19 Amicus Therapeutics, Inc. Hydroxy piperidine derivatives to treat Gaucher disease
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CN105126086B (zh) 2009-07-28 2019-05-14 夏尔人类遗传性治疗公司 用于治疗戈谢病的组合物和方法
CN102625801B (zh) * 2009-09-04 2015-09-09 联合治疗公司 治疗痘病毒感染的方法
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JP7046003B2 (ja) 2016-03-30 2022-04-01 アミカス セラピューティックス インコーポレイテッド 高ｍ６ｐ組換えタンパク質の選択方法
CN112294806B (zh) * 2020-10-26 2022-11-29 西北农林科技大学 1-甲酰基-β-咔啉衍生物用于制备抗新城疫病毒药物的应用

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Also Published As

Publication number Publication date
EP1196190B1 (de) 2003-03-19
US20020127213A1 (en) 2002-09-12
CA2378776A1 (en) 2001-02-01
AU6050600A (en) 2001-02-13
DE60001745T2 (de) 2004-03-04
JP2003505430A (ja) 2003-02-12
DE60001745D1 (de) 2003-04-24
US6495570B2 (en) 2002-12-17
WO2001007078A1 (en) 2001-02-01
EP1196190A1 (de) 2002-04-17
US6696059B2 (en) 2004-02-24
US20010044453A1 (en) 2001-11-22

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