ATE229538T1 - 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose - Google Patents

22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose

Info

Publication number
ATE229538T1
ATE229538T1 AT00910752T AT00910752T ATE229538T1 AT E229538 T1 ATE229538 T1 AT E229538T1 AT 00910752 T AT00910752 T AT 00910752T AT 00910752 T AT00910752 T AT 00910752T AT E229538 T1 ATE229538 T1 AT E229538T1
Authority
AT
Austria
Prior art keywords
alkyl
hydrogen
hydroxycholesta
meiosis
designates
Prior art date
Application number
AT00910752T
Other languages
English (en)
Inventor
Dirk Leysen
Van Der Jaap Louw
Robert Gerard Jules Ma Hanssen
Anja Wiersma
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE229538T1 publication Critical patent/ATE229538T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00910752T 1999-03-09 2000-03-03 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose ATE229538T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99200680 1999-03-09
PCT/EP2000/001780 WO2000053618A1 (en) 1999-03-09 2000-03-03 22r-hydroxycholesta-8,14-diene derivatives for the inhibition of meiosis

Publications (1)

Publication Number Publication Date
ATE229538T1 true ATE229538T1 (de) 2002-12-15

Family

ID=8239958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00910752T ATE229538T1 (de) 1999-03-09 2000-03-03 22r-hydroxycholesta-8,14-diene derivate zur hemmung der meiose

Country Status (9)

Country Link
US (1) US6518262B1 (de)
EP (1) EP1163258B1 (de)
JP (1) JP2002539134A (de)
AT (1) ATE229538T1 (de)
AU (1) AU3285000A (de)
DE (1) DE60000978T2 (de)
DK (1) DK1163258T3 (de)
ES (1) ES2188515T3 (de)
WO (1) WO2000053618A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2204613T3 (es) * 1999-04-06 2004-05-01 Akzo Nobel N.V. Androgenos 7-alfa alquilo oralmente activos.
GB9930533D0 (en) * 1999-12-23 2000-02-16 Mitsubishi Tokyo Pharm Inc Nucleic acid delivery
EP1272618A2 (de) * 2000-04-06 2003-01-08 Novo Nordisk A/S Synchronisation vom cytoplasmatischen und nuklearen reifen von oocyten in-vitro
US9532994B2 (en) 2003-08-29 2017-01-03 The Regents Of The University Of California Agents and methods for enhancing bone formation by oxysterols in combination with bone morphogenic proteins
US9670244B2 (en) 2006-02-27 2017-06-06 The Regents Of The University Of California Oxysterol compounds and the hedgehog pathway
EP2231164A1 (de) 2007-12-03 2010-09-29 The Regents of the University of California Oxysterole zur aktivierung von hedgehog-signalisierung, osteoinduktion, antiadipogenese und wnt-signalisierung
KR20150013232A (ko) 2012-05-07 2015-02-04 더 리전트 오브 더 유니버시티 오브 캘리포니아 골형성 및 헤지호그 신호전달을 유도하고 지방생성을 억제하는 옥시스테롤 유사체 oxy133
WO2014179756A1 (en) 2013-05-02 2014-11-06 The Regents Of The University Of California Bone-selective osteogenic oxysterol-bone targeting agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES472877A1 (es) * 1977-08-29 1979-02-16 Searle & Co Procedimiento para preparar derivados de 25-alquilcolesterol
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
AU717180B2 (en) * 1995-03-06 2000-03-16 Novo Nordisk A/S Stimulation of meiosis
EP0946584B1 (de) 1996-12-20 2003-04-23 Novo Nordisk A/S Verbindungen zur Regulierung der Meiose

Also Published As

Publication number Publication date
AU3285000A (en) 2000-09-28
ES2188515T3 (es) 2003-07-01
EP1163258A1 (de) 2001-12-19
US6518262B1 (en) 2003-02-11
EP1163258B1 (de) 2002-12-11
DE60000978D1 (de) 2003-01-23
WO2000053618A1 (en) 2000-09-14
DK1163258T3 (da) 2003-03-31
JP2002539134A (ja) 2002-11-19
DE60000978T2 (de) 2003-07-17

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties