ATE227120T1 - Vorrichtungen zur intravaginalen verabreichung von testosteron und testosteron- vorläuferverbindungen - Google Patents
Vorrichtungen zur intravaginalen verabreichung von testosteron und testosteron- vorläuferverbindungenInfo
- Publication number
- ATE227120T1 ATE227120T1 AT98921701T AT98921701T ATE227120T1 AT E227120 T1 ATE227120 T1 AT E227120T1 AT 98921701 T AT98921701 T AT 98921701T AT 98921701 T AT98921701 T AT 98921701T AT E227120 T1 ATE227120 T1 AT E227120T1
- Authority
- AT
- Austria
- Prior art keywords
- testosterone
- devices
- precursor compounds
- intravaginal administration
- precursor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IE970333 | 1997-05-07 | ||
PCT/IE1998/000033 WO1998050016A2 (en) | 1997-05-07 | 1998-05-07 | Intravaginal drug delivery devices for the administration of testosterone and testosterone precursors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE227120T1 true ATE227120T1 (de) | 2002-11-15 |
Family
ID=11041465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98921701T ATE227120T1 (de) | 1997-05-07 | 1998-05-07 | Vorrichtungen zur intravaginalen verabreichung von testosteron und testosteron- vorläuferverbindungen |
Country Status (15)
Country | Link |
---|---|
US (1) | US6416780B1 (de) |
EP (1) | EP0981327B1 (de) |
JP (1) | JP2001524124A (de) |
CN (1) | CN1184957C (de) |
AT (1) | ATE227120T1 (de) |
AU (1) | AU741482B2 (de) |
CA (1) | CA2288046C (de) |
DE (1) | DE69809222T2 (de) |
DK (1) | DK0981327T3 (de) |
ES (1) | ES2187024T3 (de) |
IL (1) | IL132702A0 (de) |
NO (1) | NO995419L (de) |
NZ (1) | NZ501236A (de) |
PT (1) | PT981327E (de) |
WO (1) | WO1998050016A2 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
ES2388731T5 (es) * | 2002-03-27 | 2018-01-19 | Warner Chilcott (Ireland) Limited | Dispositivos de administración de fármacos mediante una matriz intravaginal |
US8399013B2 (en) * | 2003-06-26 | 2013-03-19 | Poly-Med, Inc. | Partially absorbable fiber-reinforced composites for controlled drug delivery |
US8404272B2 (en) * | 2003-06-26 | 2013-03-26 | Poly-Med, Inc. | Fiber-reinforced composite rings for intravaginal controlled drug delivery |
EP3470108A1 (de) | 2004-07-02 | 2019-04-17 | Mati Therapeutics Inc. | Vorrichtung zur abgabe eines behandlungsmittels im auge |
MY145694A (en) | 2005-04-11 | 2012-03-30 | Xenon Pharmaceuticals Inc | Spiroheterocyclic compounds and their uses as therapeutic agents |
MY158766A (en) | 2005-04-11 | 2016-11-15 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
ES2400091T3 (es) * | 2005-08-11 | 2013-04-05 | Massachusetts Institute Of Technology | Dispositivo de suministro de fármacos intravesical y método |
DK2010096T3 (en) | 2006-03-31 | 2017-10-02 | Mati Therapeutics Inc | NASOLACRIMAL DRAINAGE SYSTEM IMPLANTS FOR PHARMACEUTICAL THERAPY |
BRPI0719210A2 (pt) | 2006-10-12 | 2015-05-05 | Xenon Pharmaceuticals Inc | Uso de compostos espiro-oxindol como agentes terapêuticos |
CN101896221B (zh) | 2007-12-11 | 2013-06-05 | 麻省理工学院 | 用于治疗膀胱和其它体囊或体腔的可植入式药物递送设备和方法 |
SI2249757T1 (sl) * | 2008-02-04 | 2017-10-30 | Ferring B.V. | Monolitni intravaginalni obroč, ki vsebuje progesteron ter postopki za njegovo izdelavo in uporabo |
US9034365B2 (en) | 2008-05-20 | 2015-05-19 | Poly-Med, Inc. | Biostable, multipurpose, microbicidal intravaginal devices |
KR101689786B1 (ko) | 2008-08-09 | 2016-12-26 | 메사츄세츠 인스티튜트 어브 테크놀로지 | 남성 비뇨생식기 및 주위 조직을 치료하는 방법 및 체내이식형 약물 전달 장치 |
CA2741029A1 (en) | 2008-10-17 | 2010-04-22 | Xenon Pharmaceuticals Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
US8101647B2 (en) | 2008-10-17 | 2012-01-24 | Xenon Pharmaceuticals Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
WO2010078307A1 (en) | 2008-12-29 | 2010-07-08 | Xenon Pharmaceuticals Inc. | Spiro-oxindole-derivatives as sodium channel blockers |
CN102470237A (zh) | 2009-06-26 | 2012-05-23 | 塔里斯生物医药公司 | 用于可植入药物递送装置的固体药物片剂 |
AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
US9017312B2 (en) * | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
EP2488531B1 (de) | 2009-10-14 | 2014-03-26 | Xenon Pharmaceuticals Inc. | Verfahren zur herstellung von spiro-oxindol derivaten |
EP3266444A1 (de) | 2010-02-26 | 2018-01-10 | Xenon Pharmaceuticals Inc. | Pharmazeutische zusammensetzungen einer spirooxindolverbindung zur topischen verabreichung und deren verwendung als therapeutika |
WO2012096985A1 (en) | 2011-01-10 | 2012-07-19 | Taris Biomedical, Inc. | Lidocaine regimen for the use of sustained treatment of bladder pain and irritative voiding |
BR112013019410A2 (pt) | 2011-02-04 | 2019-09-24 | Taris Biomedical Inc | dispositivo implantável para liberação controlada de fármaco de solubilidade baixa |
WO2013030679A2 (en) | 2011-08-29 | 2013-03-07 | Qlt Inc. | Sustained release delivery of active agents to treat glaucoma and ocular hypertension |
US9974685B2 (en) | 2011-08-29 | 2018-05-22 | Mati Therapeutics | Drug delivery system and methods of treating open angle glaucoma and ocular hypertension |
US9630929B2 (en) | 2011-10-31 | 2017-04-25 | Xenon Pharmaceuticals Inc. | Benzenesulfonamide compounds and their use as therapeutic agents |
WO2014144658A1 (en) | 2013-03-15 | 2014-09-18 | The Regents Of The University Of California | Dual reactivity potent kunitz inhibitor of fibrinolysis |
CN105163794B (zh) | 2013-03-15 | 2020-03-27 | 塔里斯生物医药公司 | 具有药物可渗透部件的药物递送装置和方法 |
WO2015026813A1 (en) | 2013-08-19 | 2015-02-26 | Taris Biomedical Llc | Multi-unit drug delivery devices and methods |
CN104546668B (zh) * | 2013-10-23 | 2019-03-05 | 国家卫生计生委科学技术研究所 | 液体硅橡胶为载体的药物缓控释***的制备及应用 |
PL2982352T3 (pl) * | 2014-06-28 | 2019-01-31 | Laboratorios Andrómaco S.A. | Krążek szyjki macicy zawierający progesteron do długotrwałego, przedłużonego i ciągłego uwalniania, stosowany w celu zapobiegania przed przedwczesnym porodem |
WO2016127068A1 (en) | 2015-02-05 | 2016-08-11 | Teva Pharmaceuticals International Gmbh | Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound |
US10894150B2 (en) | 2015-04-23 | 2021-01-19 | Taris Biomedical Llc | Drug delivery devices with drug-permeable component and methods |
CN109071542B (zh) | 2016-02-19 | 2021-07-20 | 凤凰分子设计公司 | 可用作rsk抑制剂的羧酰胺衍生物 |
JP6938545B2 (ja) | 2016-05-20 | 2021-09-22 | ゼノン・ファーマシューティカルズ・インコーポレイテッドXenon Pharmaceuticals Inc. | ベンゼンスルホンアミド化合物および治療剤としてのそれらの使用 |
SG10201912376VA (en) | 2016-12-09 | 2020-02-27 | Xenon Pharmaceuticals Inc | Benzenesulfonamide compounds and their use as therapeutic agents |
CR20200613A (es) | 2018-06-13 | 2021-06-10 | Xenon Pharmaceuticals Inc | Compuestos de bencenosulfonamida y su uso como agentes terapéuticos |
US20200030260A1 (en) | 2018-07-27 | 2020-01-30 | Xenon Pharmaceuticals Inc. | Method for treating epilepsy |
MA53488A (fr) | 2018-08-31 | 2021-12-08 | Xenon Pharmaceuticals Inc | Composés de sulfonamide substitués par hétéroaryle et leur utilisation en tant qu'inhibiteurs de canaux sodiques |
US10981905B2 (en) | 2018-08-31 | 2021-04-20 | Xenon Pharmaceuticals Inc. | Heteroaryl-substituted sulfonamide compounds and their use as therapeutic agents |
US11813354B1 (en) | 2019-01-11 | 2023-11-14 | Shear Kershman Laboratories, Inc | Trans-mucosal delivery system for testosterone |
AU2020222056A1 (en) | 2019-02-11 | 2021-10-07 | Phoenix Molecular Designs | Crystalline forms of an RSK inhibitor |
AU2022349462A1 (en) | 2021-09-24 | 2024-04-11 | Xenon Pharmaceuticals Inc. | Pyridine derivatives and their use as sodium channel activators |
IL311056A (en) | 2021-09-24 | 2024-04-01 | Xenon Pharmaceuticals Inc | Pyridine derivatives as sodium channel activators |
WO2023049367A1 (en) | 2021-09-24 | 2023-03-30 | Xenon Pharmaceuticals Inc. | Pyridinylacetamide derivatives as sodium channel activators |
TW202404583A (zh) | 2022-06-08 | 2024-02-01 | 加拿大商再諾製藥公司 | 吡啶胺衍生物及其作為鉀通道調節劑之用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3920805A (en) | 1971-12-09 | 1975-11-18 | Upjohn Co | Pharmaceutical devices and method |
GB2079158B (en) * | 1980-06-09 | 1985-01-09 | Ahi Operations Ltd | Intra-vaginal devices |
US5340585A (en) * | 1991-04-12 | 1994-08-23 | University Of Southern California | Method and formulations for use in treating benign gynecological disorders |
IL116433A (en) * | 1994-12-19 | 2002-02-10 | Galen Chemicals Ltd | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS |
-
1998
- 1998-05-07 PT PT98921701T patent/PT981327E/pt unknown
- 1998-05-07 US US09/423,324 patent/US6416780B1/en not_active Expired - Lifetime
- 1998-05-07 JP JP54787898A patent/JP2001524124A/ja active Pending
- 1998-05-07 CN CNB988049139A patent/CN1184957C/zh not_active Expired - Lifetime
- 1998-05-07 IL IL13270298A patent/IL132702A0/xx not_active IP Right Cessation
- 1998-05-07 NZ NZ501236A patent/NZ501236A/en not_active IP Right Cessation
- 1998-05-07 DE DE69809222T patent/DE69809222T2/de not_active Expired - Lifetime
- 1998-05-07 ES ES98921701T patent/ES2187024T3/es not_active Expired - Lifetime
- 1998-05-07 DK DK98921701T patent/DK0981327T3/da active
- 1998-05-07 CA CA002288046A patent/CA2288046C/en not_active Expired - Fee Related
- 1998-05-07 EP EP98921701A patent/EP0981327B1/de not_active Expired - Lifetime
- 1998-05-07 WO PCT/IE1998/000033 patent/WO1998050016A2/en active IP Right Grant
- 1998-05-07 AU AU74469/98A patent/AU741482B2/en not_active Expired
- 1998-05-07 AT AT98921701T patent/ATE227120T1/de not_active IP Right Cessation
-
1999
- 1999-11-05 NO NO995419A patent/NO995419L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2001524124A (ja) | 2001-11-27 |
NO995419L (no) | 2000-01-07 |
EP0981327A2 (de) | 2000-03-01 |
DK0981327T3 (da) | 2003-03-10 |
IL132702A0 (en) | 2001-03-19 |
DE69809222D1 (de) | 2002-12-12 |
AU741482B2 (en) | 2001-11-29 |
ES2187024T3 (es) | 2003-05-16 |
EP0981327B1 (de) | 2002-11-06 |
CA2288046C (en) | 2006-10-03 |
NO995419D0 (no) | 1999-11-05 |
US6416780B1 (en) | 2002-07-09 |
CA2288046A1 (en) | 1998-11-12 |
DE69809222T2 (de) | 2003-08-14 |
WO1998050016A2 (en) | 1998-11-12 |
WO1998050016A3 (en) | 1999-02-04 |
CN1184957C (zh) | 2005-01-19 |
PT981327E (pt) | 2003-02-28 |
NZ501236A (en) | 2002-02-01 |
CN1255056A (zh) | 2000-05-31 |
AU7446998A (en) | 1998-11-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 0981327 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |