ATE221049T1 - Verfahren zur herstellung eines zwischenprodukts in der cisapridsynthese - Google Patents

Verfahren zur herstellung eines zwischenprodukts in der cisapridsynthese

Info

Publication number
ATE221049T1
ATE221049T1 AT97913145T AT97913145T ATE221049T1 AT E221049 T1 ATE221049 T1 AT E221049T1 AT 97913145 T AT97913145 T AT 97913145T AT 97913145 T AT97913145 T AT 97913145T AT E221049 T1 ATE221049 T1 AT E221049T1
Authority
AT
Austria
Prior art keywords
fluorophenoxy
cis
methoxy
propyl
cisapride
Prior art date
Application number
AT97913145T
Other languages
English (en)
Inventor
Knaep Alfons Gaston Maria De
Luc Jozef Raphael Moens
Max Rey
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE221049T1 publication Critical patent/ATE221049T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT97913145T 1996-10-15 1997-10-09 Verfahren zur herstellung eines zwischenprodukts in der cisapridsynthese ATE221049T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96202860 1996-10-15
PCT/EP1997/005692 WO1998016511A1 (en) 1996-10-15 1997-10-09 Synthesis of cisapride

Publications (1)

Publication Number Publication Date
ATE221049T1 true ATE221049T1 (de) 2002-08-15

Family

ID=8224493

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97913145T ATE221049T1 (de) 1996-10-15 1997-10-09 Verfahren zur herstellung eines zwischenprodukts in der cisapridsynthese

Country Status (12)

Country Link
US (1) US6218542B1 (de)
EP (1) EP0934272B1 (de)
JP (1) JP2001501960A (de)
KR (1) KR100469030B1 (de)
CN (1) CN1135222C (de)
AT (1) ATE221049T1 (de)
AU (1) AU5050098A (de)
CA (1) CA2263692C (de)
DE (1) DE69714279T2 (de)
ES (1) ES2180032T3 (de)
WO (1) WO1998016511A1 (de)
ZA (1) ZA979194B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100336400B1 (ko) * 2000-03-29 2002-05-13 김건복 시사프라이드의 제조 방법
KR20100026641A (ko) * 2008-09-01 2010-03-10 동아제약주식회사 신규한 벤즈아미드 유도체 화합물 및 그의 제조방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH19942A (en) 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
CA1192218A (en) * 1981-09-16 1985-08-20 Zeneca Ag Products Inc. Isomer enrichment process for cyclopropanecarboxylates
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
ES2002640A6 (es) * 1987-03-11 1988-09-01 Alonga Lab Procedimiento de obtencion de un derivado del acido-4-amino-5-cloro-2-metoxibenzoico
US5047581A (en) * 1989-08-25 1991-09-10 Fmc Corporation Isolation of cis-isomers from isomeric mixtures of cis/transcyclopropanecarboxylates
CA2139636A1 (en) * 1992-07-07 1994-01-20 Nancy M. Gray Methods of using (+) cisapride for the treatment of gastro-esophageal reflux disease and other disorders
EP1145715A3 (de) * 1992-07-07 2004-05-19 Sepracor Inc. Verfahren zur Verwendung von (-) Cisapride zur Behandlung von Magenspeiseroehrenruechstornung und anderen Erkrankungen
US5712293A (en) * 1995-06-07 1998-01-27 Sepracor, Inc. Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride
US5739151A (en) * 1996-07-19 1998-04-14 Sepracor Inc. Method for treating emesis and central nervous system disorders using optically pure (+) norcisapride

Also Published As

Publication number Publication date
DE69714279T2 (de) 2003-03-06
KR100469030B1 (ko) 2005-01-31
ES2180032T3 (es) 2003-02-01
CN1233240A (zh) 1999-10-27
DE69714279D1 (de) 2002-08-29
US6218542B1 (en) 2001-04-17
KR20000035794A (ko) 2000-06-26
EP0934272A1 (de) 1999-08-11
JP2001501960A (ja) 2001-02-13
AU5050098A (en) 1998-05-11
ZA979194B (en) 1999-04-14
EP0934272B1 (de) 2002-07-24
CA2263692C (en) 2004-06-22
CN1135222C (zh) 2004-01-21
CA2263692A1 (en) 1998-04-23
WO1998016511A1 (en) 1998-04-23

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Legal Events

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