ATE219053T1 - Neue vitamin d-analoga - Google Patents
Neue vitamin d-analogaInfo
- Publication number
- ATE219053T1 ATE219053T1 AT98947397T AT98947397T ATE219053T1 AT E219053 T1 ATE219053 T1 AT E219053T1 AT 98947397 T AT98947397 T AT 98947397T AT 98947397 T AT98947397 T AT 98947397T AT E219053 T1 ATE219053 T1 AT E219053T1
- Authority
- AT
- Austria
- Prior art keywords
- carbon atom
- hydroxy
- hydrogen
- groups
- hydrocarbylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9721156.9A GB9721156D0 (en) | 1997-10-06 | 1997-10-06 | Novel vitamin d analogues |
| PCT/DK1998/000423 WO1999018070A1 (en) | 1997-10-06 | 1998-10-02 | Novel vitamin d analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219053T1 true ATE219053T1 (de) | 2002-06-15 |
Family
ID=10820110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98947397T ATE219053T1 (de) | 1997-10-06 | 1998-10-02 | Neue vitamin d-analoga |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6399797B1 (de) |
| EP (1) | EP1023263B1 (de) |
| JP (1) | JP2001519327A (de) |
| KR (1) | KR20010030966A (de) |
| CN (1) | CN1140509C (de) |
| AT (1) | ATE219053T1 (de) |
| AU (1) | AU740457B2 (de) |
| CA (1) | CA2304152A1 (de) |
| CZ (1) | CZ295955B6 (de) |
| DE (1) | DE69806035T2 (de) |
| DK (1) | DK1023263T3 (de) |
| ES (1) | ES2175784T3 (de) |
| GB (1) | GB9721156D0 (de) |
| HK (1) | HK1031868A1 (de) |
| HU (1) | HUP0004226A3 (de) |
| NZ (1) | NZ503344A (de) |
| PL (1) | PL193060B1 (de) |
| PT (1) | PT1023263E (de) |
| RU (1) | RU2196132C2 (de) |
| WO (1) | WO1999018070A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60117762T2 (de) * | 2000-03-27 | 2006-10-12 | Wisconsin Alumni Research Foundation, Madison | Vitamin d-verbindung zur behandlung von chronischer tranplantatnephropatie bei nieren transplantierten patienten |
| EP1458678A1 (de) * | 2002-11-18 | 2004-09-22 | Teva Pharmaceutical Industries Limited | Kristallisationsverfahren zur reinigung von calcipotriene |
| WO2006051106A1 (en) | 2004-11-12 | 2006-05-18 | Bioxell Spa | Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer |
| JP2008520705A (ja) * | 2004-11-22 | 2008-06-19 | ウィスコンシン・アルムニ・リサーチ・ファウンデーション | ２−メチレン−１９−ノル−１α−ヒドロキシ−１７−エン−ホモプレグナカルシフェロールおよびその使用 |
| US8193169B2 (en) * | 2006-04-06 | 2012-06-05 | Wisconsin Alumni Research Foundation | (20R)-2α-methyl-19,26,2-trinor-vitamin D analogs |
| BRPI0715636A2 (pt) * | 2006-08-29 | 2013-07-02 | Teva Pharma | composiÇÕes farmacologicamente ativas estÁveis incluindo compostos contendo vitamina d e corticosteràide com compatibilidade para ph baixo |
| US7888339B2 (en) | 2008-07-10 | 2011-02-15 | Wisconsin Alumni Research Foundation | 2-methylene-20(21)-dehydro-19-nor-vitamin D analogs |
| US7648974B1 (en) * | 2008-07-10 | 2010-01-19 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 3,2-dihydrofuran ring |
| US8222236B2 (en) | 2008-07-10 | 2012-07-17 | Wisconsin Alumni Research Foundation | 2-methylene-(20E)-20(22)-dehydro-19-nor-vitamin D analogs |
| US8399439B2 (en) * | 2008-07-10 | 2013-03-19 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20S,22E,25R)-vitamin D analogs |
| US7879829B2 (en) * | 2008-07-10 | 2011-02-01 | Wisconsin Alumni Research Foundation | 19-nor-vitamin D analogs with 1,2-dihydrofuran ring |
| US7713953B2 (en) * | 2008-07-10 | 2010-05-11 | Wisconsin Alumni Research Foundation | 2-methylene-(22E)-25-(1-methylene-hexyl)-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs |
| US7893043B2 (en) | 2008-07-10 | 2011-02-22 | Wisconsin Alumni Research Foundation | 2-methylene-(17Z)-17(20)-dehydro-19,21-dinor-vitamin D analogs |
| US8193170B2 (en) | 2008-07-10 | 2012-06-05 | Wisconsin Alumni Research Foundation | 2-methylene-19,26-dinor-(20R,22E,25R)-vitamin D analogs |
| AU2010208323B2 (en) * | 2009-01-27 | 2016-03-10 | Berg Llc | Vitamin D3 and analogs thereof for alleviating side effects associated with chemotherapy |
| EP2464357B1 (de) | 2009-08-14 | 2019-05-22 | Berg LLC | Vitamin d3 und analoge davon zur behandlung von alopezie |
| WO2011041596A2 (en) | 2009-10-02 | 2011-04-07 | Wisconsin Alumni Research Foundation | 19-nor-vitamin d analogs with 1,2-or 3,2-cyclopentene ring |
| JP2013506685A (ja) | 2009-10-02 | 2013-02-28 | ウィスコンシン・アルムニ・リサーチ・ファウンデーション | （２０Ｓ，２２Ｅ）−２−メチレン−１９−ノル−２２−エン−１α，２５−ジヒドロキシビタミンＤ３類似体 |
| JP6059716B2 (ja) | 2011-06-03 | 2017-01-11 | ウイスコンシン アラムニ リサーチ ファンデーション | （２２Ｅ）−２−メチレン−２６，２７−シクロ−２２−デヒドロ−１α−ヒドロキシ−１９−ノルビタミンＤ３誘導体 |
| US10479764B2 (en) | 2011-06-28 | 2019-11-19 | Wisconsin Alumni Research Foundation | 2-methylene-(22E)-25-hexanoyl-24-oxo-26,27-cyclo-22-dehydro-19-nor-vitamin D analogs |
| WO2013012644A1 (en) | 2011-07-18 | 2013-01-24 | Wisconsin Alumni I Research Foundation | 2-methylene-20(21)-dehydro-19,24,25,26,27,-pentanor-vitamin d analogs |
| US9416102B2 (en) | 2013-01-23 | 2016-08-16 | Wisconsin Alumni Research Foundation | (22E)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 analogs |
| KR20160013201A (ko) | 2013-05-29 | 2016-02-03 | 버그 엘엘씨 | 비타민 d를 이용한 화학요법 유발 탈모증의 예방 또는 완화 |
| CN114593917A (zh) * | 2022-03-08 | 2022-06-07 | 安徽理工大学 | 一种基于三元组模型的小样本轴承故障诊断方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2091515T3 (es) * | 1992-05-20 | 1996-11-01 | Hoffmann La Roche | Analogos fluorados de la vitamina d3. |
| GB9214202D0 (en) | 1992-07-03 | 1992-08-12 | Leo Pharm Prod Ltd | Chemical compounds |
| US5565589A (en) | 1993-11-03 | 1996-10-15 | Wisconsin Alumni Research Foundation | 17-formyl-5,6-trans-vitamin D compounds |
| EP0717034B1 (de) * | 1994-12-14 | 1999-04-07 | Duphar International Research B.V | Vitamin-D-Derivate und Verfahren zur Herstellung dieser Verbindungen |
-
1997
- 1997-10-06 GB GBGB9721156.9A patent/GB9721156D0/en not_active Ceased
-
1998
- 1998-10-02 CZ CZ20001178A patent/CZ295955B6/cs not_active IP Right Cessation
- 1998-10-02 JP JP2000514882A patent/JP2001519327A/ja active Pending
- 1998-10-02 DK DK98947397T patent/DK1023263T3/da active
- 1998-10-02 AU AU94323/98A patent/AU740457B2/en not_active Ceased
- 1998-10-02 PT PT98947397T patent/PT1023263E/pt unknown
- 1998-10-02 CN CNB988099330A patent/CN1140509C/zh not_active Expired - Fee Related
- 1998-10-02 NZ NZ503344A patent/NZ503344A/en unknown
- 1998-10-02 DE DE69806035T patent/DE69806035T2/de not_active Expired - Fee Related
- 1998-10-02 KR KR1020007003717A patent/KR20010030966A/ko not_active Application Discontinuation
- 1998-10-02 US US09/543,418 patent/US6399797B1/en not_active Expired - Fee Related
- 1998-10-02 HU HU0004226A patent/HUP0004226A3/hu unknown
- 1998-10-02 RU RU2000111255/04A patent/RU2196132C2/ru not_active IP Right Cessation
- 1998-10-02 AT AT98947397T patent/ATE219053T1/de not_active IP Right Cessation
- 1998-10-02 EP EP98947397A patent/EP1023263B1/de not_active Expired - Lifetime
- 1998-10-02 CA CA002304152A patent/CA2304152A1/en not_active Abandoned
- 1998-10-02 ES ES98947397T patent/ES2175784T3/es not_active Expired - Lifetime
- 1998-10-02 WO PCT/DK1998/000423 patent/WO1999018070A1/en not_active Application Discontinuation
- 1998-10-02 PL PL339668A patent/PL193060B1/pl unknown
-
2001
- 2001-04-10 HK HK01102530A patent/HK1031868A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1023263E (pt) | 2002-10-31 |
| HK1031868A1 (en) | 2001-06-29 |
| CN1140509C (zh) | 2004-03-03 |
| CN1274344A (zh) | 2000-11-22 |
| JP2001519327A (ja) | 2001-10-23 |
| DE69806035T2 (de) | 2003-01-30 |
| WO1999018070A1 (en) | 1999-04-15 |
| EP1023263A1 (de) | 2000-08-02 |
| HUP0004226A3 (en) | 2001-10-29 |
| HUP0004226A2 (hu) | 2001-04-28 |
| CA2304152A1 (en) | 1999-04-15 |
| DK1023263T3 (da) | 2002-12-02 |
| PL339668A1 (en) | 2001-01-02 |
| ES2175784T3 (es) | 2002-11-16 |
| DE69806035D1 (de) | 2002-07-18 |
| AU740457B2 (en) | 2001-11-01 |
| NZ503344A (en) | 2002-04-26 |
| CZ295955B6 (cs) | 2005-12-14 |
| GB9721156D0 (en) | 1997-12-03 |
| CZ20001178A3 (cs) | 2000-09-13 |
| US6399797B1 (en) | 2002-06-04 |
| EP1023263B1 (de) | 2002-06-12 |
| AU9432398A (en) | 1999-04-27 |
| KR20010030966A (ko) | 2001-04-16 |
| RU2196132C2 (ru) | 2003-01-10 |
| PL193060B1 (pl) | 2007-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |