ATE214396T1 - Kombinatorische bibliotheken aus markierten biochemischen verbindungen und verfahren zu ihrer herstellung - Google Patents

Kombinatorische bibliotheken aus markierten biochemischen verbindungen und verfahren zu ihrer herstellung

Info

Publication number
ATE214396T1
ATE214396T1 AT96919473T AT96919473T ATE214396T1 AT E214396 T1 ATE214396 T1 AT E214396T1 AT 96919473 T AT96919473 T AT 96919473T AT 96919473 T AT96919473 T AT 96919473T AT E214396 T1 ATE214396 T1 AT E214396T1
Authority
AT
Austria
Prior art keywords
labeled
methods
labeled biochemical
biochemical compounds
combinatorial libraries
Prior art date
Application number
AT96919473T
Other languages
English (en)
Inventor
Jonathan M Brown
F C Thomas Allnutt
Hao Chen
Richard Radmer
Original Assignee
Martek Biosciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Martek Biosciences Corp filed Critical Martek Biosciences Corp
Application granted granted Critical
Publication of ATE214396T1 publication Critical patent/ATE214396T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Indole Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
AT96919473T 1995-06-21 1996-06-13 Kombinatorische bibliotheken aus markierten biochemischen verbindungen und verfahren zu ihrer herstellung ATE214396T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49330095A 1995-06-21 1995-06-21
PCT/US1996/010526 WO1997000887A1 (en) 1995-06-21 1996-06-13 Combinatorial libraries of labeled biochemical compounds and methods for producing same

Publications (1)

Publication Number Publication Date
ATE214396T1 true ATE214396T1 (de) 2002-03-15

Family

ID=23959668

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919473T ATE214396T1 (de) 1995-06-21 1996-06-13 Kombinatorische bibliotheken aus markierten biochemischen verbindungen und verfahren zu ihrer herstellung

Country Status (11)

Country Link
US (1) US5741713A (de)
EP (1) EP0839152B1 (de)
JP (1) JPH11509086A (de)
AT (1) ATE214396T1 (de)
AU (1) AU6180696A (de)
CA (1) CA2225313A1 (de)
DE (1) DE69619825T2 (de)
DK (1) DK0839152T3 (de)
ES (1) ES2174075T3 (de)
PT (1) PT839152E (de)
WO (1) WO1997000887A1 (de)

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AU2105601A (en) * 1999-12-17 2001-06-25 Maxygen, Inc. Methods for parallel detection of compositions having desired characteristics bymeans of mri spectroscopy
AU9684601A (en) 2000-10-12 2002-04-22 Univ Rochester Compositions that inhibit proliferation of cancer cells
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AU2003253580A1 (en) * 2002-02-26 2003-11-17 University Of Minnesota Variants of nedd4l associated with hypertension and viral budding
ATE380772T1 (de) 2002-04-04 2007-12-15 Monsanto Technology Llc Automatisiertes system zum aufnehmen, wägen und sortieren von teilchenförmigem material
EP1575992A4 (de) 2002-08-05 2007-02-21 Univ Rochester Chimäre proteine aus proteintransduzierender domäne/deaminase, verwandte verbindungen und deren verwendungen
US20040214232A1 (en) * 2002-08-16 2004-10-28 Burke Martin D. Generation of skeletal diversity within a combinatorial library
WO2004023527A2 (en) 2002-09-05 2004-03-18 Nanosys, Inc. Nanostructure and nanocomposite based compositions and photovoltaic devices
CA2539935C (en) 2003-09-23 2015-11-17 Monsanto Technology Llc High throughput automated seed analysis system
CN101052295B (zh) 2004-08-26 2014-03-05 孟山都技术有限公司 种子自动检验
US7703238B2 (en) 2004-08-26 2010-04-27 Monsanto Technology Llc Methods of seed breeding using high throughput nondestructive seed sampling
CN101500481B (zh) 2005-04-05 2014-07-02 康宁股份有限公司 一种测定刺激事件对细胞产生的影响的方法
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2006127020A1 (en) 2005-05-19 2006-11-30 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services, Centers For Disease Control And Prevention FUNCTIONAL EPITOPES OF STREPTOCOCCUS PNEUMONIAE PsaA ANTIGEN AND USES THEREOF
DK2468847T3 (en) 2005-06-07 2017-06-06 Dsm Nutritional Products Ag EUCARYOTIC MICRO-ORGANISMS FOR THE PREPARATION OF LIPIDS AND ANTIOXIDANTS
EP2392647A1 (de) 2005-10-14 2011-12-07 MUSC Foundation For Research Development Targeting von PAX2 zur Induktion der DEFB1-vermittelten Tumorimmunität und Krebstherapie
US8080534B2 (en) * 2005-10-14 2011-12-20 Phigenix, Inc Targeting PAX2 for the treatment of breast cancer
WO2007053570A2 (en) * 2005-10-31 2007-05-10 Janssen Pharmaceutica N.V. A polypeptide complex of trpm8 and calmodulin and its uses thereof
US8028469B2 (en) 2006-03-02 2011-10-04 Monsanto Technology Llc Automated high-throughput seed sampler and methods of sampling, testing and bulking seeds
US7998669B2 (en) 2006-03-02 2011-08-16 Monsanto Technology Llc Automated contamination-free seed sampler and methods of sampling, testing and bulking seeds
GB0605584D0 (en) * 2006-03-20 2006-04-26 Olink Ab Method for analyte detection using proximity probes
CA2656676C (en) 2006-06-28 2016-04-26 Monsanto Technology Llc Small object sorting system and method
CN101981201A (zh) * 2006-08-01 2011-02-23 加拿大海洋营养食品有限公司 产油微生物及改良这些微生物的方法
EP2066812A4 (de) 2006-09-21 2010-04-28 Univ Rochester Zusammensetzungen und verfahren in zusammenhang mit proteinverschiebungstherapie für myotone dystrophie
WO2008136852A2 (en) 2006-11-01 2008-11-13 University Of Rochester Methods and compositions related to the structure and function of apobec3g
WO2008094370A2 (en) 2006-12-22 2008-08-07 University Of Utah Research Foundation Method of detecting ocular diseases and pathologic conditions and treatment of same
EP2117575A4 (de) 2007-01-03 2013-06-05 Burnham Inst Medical Research Verfahren und zusammensetzungen in verbindung mit gerinnselbindenden verbindungen
EP2596799B1 (de) 2007-02-08 2016-11-23 University of Utah Research Foundation Verfahren und Zusammensetzungen zur Viruseindringungshemmung
BRPI0811990A2 (pt) 2007-05-31 2014-09-23 Monsanto Technology Llc Separador de semente
PT2192946T (pt) 2007-09-25 2022-11-17 Otsuka Pharma Co Ltd Dispositivo no corpo com amplificação de sinal dipolo virtual
WO2010019963A2 (en) * 2008-08-15 2010-02-18 Georgetown University Na channels, disease, and related assays and compositions
US20120070443A1 (en) 2008-12-02 2012-03-22 University Of Utah Research Foundation Pde1 as a target therapeutic in heart disease
US10481167B2 (en) 2008-12-05 2019-11-19 C2N Diagnostics Methods for measuring concentrations of biomolecules
MY161146A (en) 2009-04-28 2017-04-14 Proteus Digital Health Inc Highly-reliable ingestible event markers and methods for using the same
US20120149663A1 (en) 2009-08-18 2012-06-14 Georgetown University Boronic acid compositions and methods related to cancer
US20110081293A1 (en) 2009-10-07 2011-04-07 Sanford-Burnham Medical Research Institute Methods and compositions related to clot-binding lipid compounds
EP2512497A1 (de) 2009-12-18 2012-10-24 Sanford-Burnham Medical Research Institute Verfahren und zusammensetzungen im zusammenhang mit gerinnselbindenden verbndungen
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GB201101621D0 (en) 2011-01-31 2011-03-16 Olink Ab Method and product
EP2691105B1 (de) 2011-03-28 2018-07-11 University of Utah Research Foundation Verfahren und zusammensetzungen zur viruseindringungshemmung
BR112014008862A2 (pt) 2011-10-14 2018-08-07 Genentech Inc anticorpo isolado que se liga à htra1, ácido nucleico isolado, célula hospedeira, imunoconjugado, formulação farmacêutica, métodos e usos
WO2013082307A1 (en) * 2011-12-02 2013-06-06 C2N Diagnostics Methods for measuring concentrations of biomolecules
GB201201547D0 (en) 2012-01-30 2012-03-14 Olink Ab Method and product
AU2014230945B2 (en) 2013-03-12 2019-07-11 Ventana Medical Systems, Inc. Proximity assay for in situ detection of targets
WO2014139979A1 (en) 2013-03-12 2014-09-18 Ventana Medical Systems, Inc. Quantum dot in situ hybridization
US9873880B2 (en) 2013-03-13 2018-01-23 Dsm Nutritional Products Ag Engineering microorganisms
CA2965872C (en) 2014-11-25 2022-02-22 Ventana Medical Systems, Inc. Proximity assays using chemical ligation and hapten transfer
GB201518655D0 (en) 2015-10-21 2015-12-02 Olink Ab Method for generating proximity probes
RS61871B1 (sr) 2015-10-30 2021-06-30 Hoffmann La Roche Anti-htra1 antitela i postupci za njihovu primenu
WO2019055618A1 (en) 2017-09-15 2019-03-21 Arizona Board Of Regents On Behalf Of Arizona State University METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY
KR20200127152A (ko) 2017-12-15 2020-11-10 플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 원형 폴리리보뉴클레오티드를 포함하는 조성물 및 그의 용도
WO2020180751A1 (en) 2019-03-01 2020-09-10 Flagship Pioneering Innovations Vi, Llc Compositions, methods, and kits for delivery of polyribonucleotides
US20230072532A1 (en) 2019-03-25 2023-03-09 Flagship Pioneering Innovations Vi, Llc Compositions comprising modified circular polyribonucleotides and uses thereof
AU2020292427A1 (en) 2019-06-14 2022-01-06 Flagship Pioneering Innovations Vi, Llc Circular RNAs for cellular therapy
MA56538A (fr) 2019-06-19 2022-04-27 Flagship Pioneering Innovations Vi Llc Procédés de dosage de polyribonucléotides circulaires
EP4038222A4 (de) 2019-10-02 2023-10-18 Arizona Board of Regents on behalf of Arizona State University Verfahren und zusammensetzungen zur identifizierung von neoantigenen zur verwendung bei der behandlung und vorbeugung von krebs
WO2021155171A1 (en) 2020-01-29 2021-08-05 Flagship Pioneering Innovations Vi, Llc Delivery of compositions comprising circular polyribonucleotides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0474790T3 (da) * 1989-06-14 1997-07-07 Martek Corp Medier til cellevækst og fremgangsmåde til fremstilling deraf
US5650489A (en) * 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
EP0665897B1 (de) * 1992-10-01 2003-07-09 The Trustees Of Columbia University In The City Of New York Komplexe kombinatorische chemische banken, die mit markierungen versehen sind

Also Published As

Publication number Publication date
EP0839152B1 (de) 2002-03-13
US5741713A (en) 1998-04-21
ES2174075T3 (es) 2002-11-01
PT839152E (pt) 2002-09-30
CA2225313A1 (en) 1997-01-09
AU6180696A (en) 1997-01-22
DK0839152T3 (da) 2002-07-08
JPH11509086A (ja) 1999-08-17
EP0839152A1 (de) 1998-05-06
WO1997000887A1 (en) 1997-01-09
DE69619825T2 (de) 2002-10-10
DE69619825D1 (de) 2002-04-18

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee