ATE208378T1 - Verfahren zur herstellung von nicotinsäuren - Google Patents

Verfahren zur herstellung von nicotinsäuren

Info

Publication number
ATE208378T1
ATE208378T1 AT98906497T AT98906497T ATE208378T1 AT E208378 T1 ATE208378 T1 AT E208378T1 AT 98906497 T AT98906497 T AT 98906497T AT 98906497 T AT98906497 T AT 98906497T AT E208378 T1 ATE208378 T1 AT E208378T1
Authority
AT
Austria
Prior art keywords
nicotinic
hydrogen
image
group
nicotinic acids
Prior art date
Application number
AT98906497T
Other languages
English (en)
Inventor
Padam N Sharma
Marazban H Vandrevala
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE208378T1 publication Critical patent/ATE208378T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/08—Formation or introduction of functional groups containing oxygen of carboxyl groups or salts, halides or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98906497T 1997-03-03 1998-02-18 Verfahren zur herstellung von nicotinsäuren ATE208378T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/811,087 US5739342A (en) 1997-03-03 1997-03-03 Process for the preparation of nicotinic acids
PCT/US1998/003035 WO1998039298A1 (en) 1997-03-03 1998-02-18 Process for the preparation of nicotinic acids

Publications (1)

Publication Number Publication Date
ATE208378T1 true ATE208378T1 (de) 2001-11-15

Family

ID=25205520

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98906497T ATE208378T1 (de) 1997-03-03 1998-02-18 Verfahren zur herstellung von nicotinsäuren

Country Status (13)

Country Link
US (1) US5739342A (de)
EP (1) EP0968189B1 (de)
JP (1) JP2001513108A (de)
KR (1) KR100517007B1 (de)
AT (1) ATE208378T1 (de)
AU (1) AU737619B2 (de)
CA (1) CA2282381C (de)
DE (1) DE69802388T2 (de)
DK (1) DK0968189T3 (de)
ES (1) ES2167869T3 (de)
IL (1) IL131177A (de)
PT (1) PT968189E (de)
WO (1) WO1998039298A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19926400A1 (de) * 1999-06-10 2000-12-14 Bayer Ag Verbessertes Verfahren zur Herstellung von 2,6-Dichlor-5-fluor-nicotinsäure und grobteilige und besonders reine 2,6-Dichlor-5-fluor-nicotinsäure
US7691582B2 (en) 2002-09-27 2010-04-06 The Regents Of The University Of Michigan Methods of secretory vimentin detection and modulation
US7093640B2 (en) * 2003-02-10 2006-08-22 Kitaru Innovations, Inc. Tape dispenser having a retaining and application area
EP1943209B1 (de) * 2005-09-16 2012-06-27 LG Life Sciences Ltd. Verfahren zur herstellung von beta-ketoester-verbindungen
KR102359436B1 (ko) 2015-06-05 2022-02-09 (주)아모레퍼시픽 메틸 2-프로필-6-(트리플루오로메틸) 니코티네이트의 제조방법
US11236070B2 (en) 2019-05-16 2022-02-01 Novartis Ag Chemical process
US11465872B2 (en) 2020-06-25 2022-10-11 Snj Patents, Llc Tape dispenser
CN113666867A (zh) * 2021-09-16 2021-11-19 宁夏常晟药业有限公司 一种2,6-二氯-5-氟烟酸的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS274601B2 (en) * 1983-07-27 1991-09-15 Dainippon Pharmaceutical Co Method of 1,8-naphthyridine derivative production
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
US4616019A (en) * 1984-01-26 1986-10-07 Abbott Laboratories Naphthyridine antibacterial compounds
DE3574380D1 (en) * 1984-02-17 1989-12-28 Daiichi Seiyaku Co 1,8-naphthyridine derivatives
DE3508816A1 (de) * 1985-01-10 1986-07-10 Bayer Ag, 5090 Leverkusen 6,7-disubstituierte 1-cyclopropyl-1,4-dihydro-4-oxo-1,8-naphtyridin-3-carbonsaeuren
IE62600B1 (en) * 1987-08-04 1995-02-22 Abbott Lab Naphtyridine antianaerobic compounds
EP0333020A3 (de) * 1988-03-18 1991-03-20 Abbott Laboratories Verfahren zur Herstellung von substituierten Pyridinen
US5204478A (en) * 1992-08-20 1993-04-20 Warner-Lambert Company Process for the synthesis of 2,6-dichloro-5-fluoronicotinic acid and 2,6-dichloro-5-fluoronicotinoyl chloride

Also Published As

Publication number Publication date
ES2167869T3 (es) 2002-05-16
DE69802388D1 (de) 2001-12-13
EP0968189B1 (de) 2001-11-07
EP0968189A1 (de) 2000-01-05
IL131177A0 (en) 2001-01-28
KR20000075874A (ko) 2000-12-26
AU6170798A (en) 1998-09-22
IL131177A (en) 2005-08-31
DE69802388T2 (de) 2002-08-08
DK0968189T3 (da) 2002-02-18
US5739342A (en) 1998-04-14
AU737619B2 (en) 2001-08-23
CA2282381C (en) 2007-06-12
PT968189E (pt) 2002-04-29
WO1998039298A1 (en) 1998-09-11
JP2001513108A (ja) 2001-08-28
KR100517007B1 (ko) 2005-09-27
CA2282381A1 (en) 1998-09-11

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