ATE201450T1 - Künstliche-säuger-chromosome - Google Patents

Künstliche-säuger-chromosome

Info

Publication number
ATE201450T1
ATE201450T1 AT92115694T AT92115694T ATE201450T1 AT E201450 T1 ATE201450 T1 AT E201450T1 AT 92115694 T AT92115694 T AT 92115694T AT 92115694 T AT92115694 T AT 92115694T AT E201450 T1 ATE201450 T1 AT E201450T1
Authority
AT
Austria
Prior art keywords
chromosomes
cell lines
centromeres
dna sequences
human dna
Prior art date
Application number
AT92115694T
Other languages
English (en)
Inventor
Gyula Hadlaczky
Original Assignee
Biolog Res Ct Of The Hungarian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biolog Res Ct Of The Hungarian filed Critical Biolog Res Ct Of The Hungarian
Application granted granted Critical
Publication of ATE201450T1 publication Critical patent/ATE201450T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells
    • C12N5/166Animal cells resulting from interspecies fusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT92115694T 1991-09-13 1992-09-14 Künstliche-säuger-chromosome ATE201450T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/759,558 US5288625A (en) 1991-09-13 1991-09-13 Mammalian artificial chromosomes

Publications (1)

Publication Number Publication Date
ATE201450T1 true ATE201450T1 (de) 2001-06-15

Family

ID=25056105

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92115694T ATE201450T1 (de) 1991-09-13 1992-09-14 Künstliche-säuger-chromosome

Country Status (6)

Country Link
US (1) US5288625A (de)
EP (1) EP0532050B1 (de)
JP (1) JP3456715B2 (de)
AT (1) ATE201450T1 (de)
CA (1) CA2078189C (de)
DE (1) DE69231835T2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres
US5695967A (en) * 1995-06-07 1997-12-09 Case Western Reserve University Method for stably cloning large repeating units of DNA
US6348353B1 (en) * 1995-06-07 2002-02-19 Case Western Reserve University Artificial mammalian chromosome
US5869294A (en) * 1995-06-07 1999-02-09 Case Western Reserve University Method for stably cloning large repeating DNA sequences
US6632976B1 (en) 1995-08-29 2003-10-14 Kirin Beer Kabushiki Kaisha Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene
WO1997016533A1 (en) * 1995-10-31 1997-05-09 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US6133503A (en) * 1995-10-31 2000-10-17 The Regents Of The University Of California Mammalian artificial chromosomes and methods of using same
US6077697A (en) * 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20020160970A1 (en) * 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20030033617A1 (en) * 1996-04-10 2003-02-13 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
CA2263823C (en) * 1996-08-26 2010-11-23 Tsuneko Okazaki Mammalian artificial chromosomes
US6972197B1 (en) 1999-03-18 2005-12-06 The University Of Chicago Plant chromosome compositions and methods
US7193128B2 (en) * 1997-06-03 2007-03-20 Chromatin, Inc. Methods for generating or increasing revenues from crops
US7235716B2 (en) 1997-06-03 2007-06-26 Chromatin, Inc. Plant centromere compositions
US7119250B2 (en) 1997-06-03 2006-10-10 The University Of Chicago Plant centromere compositions
US7227057B2 (en) 1997-06-03 2007-06-05 Chromatin, Inc. Plant centromere compositions
US6900012B1 (en) 1997-06-03 2005-05-31 The University Of Chicago Plant artificial chromosome compositions and methods
AU746775B2 (en) * 1997-06-03 2002-05-02 University Of Chicago, The Plant artificial chromosome (PLAC) compositions and methods
WO2000006715A1 (en) * 1998-07-27 2000-02-10 Genotypes Inc. Automatic eukaryotic artificial chromosome vector
US7989202B1 (en) 1999-03-18 2011-08-02 The University Of Chicago Plant centromere compositions
US6475794B1 (en) * 1999-10-08 2002-11-05 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
US6399374B1 (en) * 1999-10-08 2002-06-04 The Johns Hopkins University Converting diploidy to haploidy for genetic diagnosis
PT1322752E (pt) * 2000-09-28 2010-05-06 Bioriginal Food & Science Corp Fad4, fad5, fad5-2 e fad6, novos membros da família de dessaturases de ácidos gordos e susas utilizações
US6936469B2 (en) 2001-03-22 2005-08-30 Chromos Molecular Systems Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
US20030186390A1 (en) * 2001-03-22 2003-10-02 De Jong Gary Methods for delivering nucleic acid molecules into cells and assessment thereof
US7294511B2 (en) 2001-03-22 2007-11-13 Chromos Molecular Systems, Inc. Methods for delivering nucleic acid molecules into cells and assessment thereof
BR0209989A (pt) * 2001-05-30 2005-04-12 Chromos Molecular Systems Inc Plataformas baseadas em cromossomas
NZ529597A (en) * 2001-05-30 2005-12-23 Chromos Molecular Systems Inc Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes
US7439346B2 (en) * 2001-10-12 2008-10-21 Perkinelmer Las Inc. Nucleic acids arrays and methods of use therefor
AU2002367886B8 (en) 2001-10-12 2008-08-14 Perkinelmer Las, Inc. Compilations of nucleic acids and arrays and methods of using them
US7330851B2 (en) * 2003-08-18 2008-02-12 Eaglehawk, Limited Data security through dissembly of data elements or connections between elements
JP2007515947A (ja) * 2003-10-30 2007-06-21 タフツ−ニュー イングランド メディカル センター 羊水中の無細胞胎児dnaを使用する出生前診断
US8729341B2 (en) * 2004-02-23 2014-05-20 University Of Chicago Plants modified with mini-chromosomes
US20060174364A1 (en) * 2004-03-01 2006-08-03 Avigenics, Inc. Artificial chromosomes and transchromosomic avians
AU2005299413A1 (en) 2004-10-22 2006-05-04 Revivicor, Inc. Ungulates with genetically modified immune systems
EP1929019A2 (de) * 2005-09-08 2008-06-11 Chromatin, Inc. Mit minichromosomen modifizierte pflanzen
WO2007084767A2 (en) * 2006-01-20 2007-07-26 University Of South Florida Methods for profiling transcriptosomes
WO2008112972A2 (en) * 2007-03-15 2008-09-18 Chromatin, Inc. Centromere sequences and minichromosomes
EP2348827B1 (de) 2008-10-27 2015-07-01 Revivicor, Inc. Immunsupprimierte huftiere
WO2011011693A1 (en) 2009-07-23 2011-01-27 Chromatin, Inc. Sorghum centromere sequences and minichromosomes
HU230368B1 (hu) 2012-11-16 2016-03-29 Magyar Tudományos Akadémia Szegedi Biológiai Kutatóközpont Új módszer az emlős mesterséges kromoszóma több génnel való feltöltésére
US20190345259A1 (en) 2016-04-12 2019-11-14 Synploid Biotek, Llc Methods for creating synthetic chromosomes having gene regulatory systems and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4608339A (en) * 1983-10-25 1986-08-26 Yoakum George H Protoplast fusion method for high-frequency DNA transfection in human cells
US4970162A (en) * 1985-11-13 1990-11-13 The United States Of America As Represented By The Department Of Health And Human Services Human-mouse hybrid cell line expressing monocyte-macrophage properties
US4935350A (en) * 1985-11-18 1990-06-19 Amgen Materials and methods for controlling plasmid copy number and stability
FR2593827B1 (fr) * 1986-01-31 1989-12-22 Inst Nat Sante Rech Med Fragments d'adn utilisables dans des vecteurs pour le maintien hereditaire de genes etrangers a l'etat autonome dans des animaux transgeniques, procede pour leur obtention et applications biologiques
CA2006011A1 (en) * 1988-12-21 1990-06-21 Cecilia Lo Transgenic organisms and cells and methods of producing transgenic organisms and cells
CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres

Also Published As

Publication number Publication date
JP3456715B2 (ja) 2003-10-14
DE69231835T2 (de) 2001-11-22
EP0532050A2 (de) 1993-03-17
CA2078189C (en) 1999-12-14
EP0532050A3 (en) 1993-07-21
US5288625A (en) 1994-02-22
DE69231835D1 (de) 2001-06-28
JPH07177881A (ja) 1995-07-18
EP0532050B1 (de) 2001-05-23
CA2078189A1 (en) 1993-03-14

Similar Documents

Publication Publication Date Title
ATE201450T1 (de) Künstliche-säuger-chromosome
ATE250134T1 (de) Säuger-zentromere mit menschlicher dns, die mit einem dominanten marker assoziiert sind
Stebbins The basis of progressive evolution
ATE403733T1 (de) Künstliche säuger chromosome
SG48760A1 (en) Generation of xenogenetic antibodies
DK0791058T3 (da) Anvendelse af en nukleotidsekvens, der koder for enzymet I-SCEI
ATE198355T1 (de) Alpha-amidierende enzymzusammensetzungen und verfahren zu deren herstellung und verwendung
DE69841452D1 (de) Humanes Chromosomfragment und ein Vektor, der dies enthält
HK1007330A1 (en) Generation of xenogeneic antibodies
ATE120486T1 (de) Vektor zur integrationsstellenunabhängigen genexpression in säugetier-wirtszellen.
DK224185A (da) Vektor til inkorporering i gaercellers chromosomer
SE8104700L (sv) Eukaryotiskt autonomt replikerande segment
CO4810249A1 (es) Metodo para la seleccion de plantas transformadas .
DK0596881T3 (da) Ekspression i ikke-tumurale humane lymofoblastoider med en integrativ vektor
IL97048A0 (en) Bioluminescence assay for gene expression in growing mammalian cells
ATE263837T1 (de) Expressionsteigerung durch gentargeting in endogene retrovirus-ähnliche sequenzen
NO974367L (no) Vektorer samt fremgangsmåter for gen-ekspresjon i pattedyrceller
ATE259421T1 (de) Dna-virus-vektoren und verfahren zu ihrer herstellung
BARRETT Methods for Risk Assessment of Transgenic Plants. II Pollination, Gene Transfer, and Population Impacts. By Gösta Kjellsson, Vibeke Simonsen and Klaus Ammann. Birkhauser Verlag. 1997. 308+ ix pages. Price DM98. ISBN 3-7643-5696-0 (Basel), 0-8176-5696-0 (Boston).
DE60017909D1 (de) Kartierung von genen basierend auf transkription

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties