ATE192732T1 - Caroboxy- oder tetrazolengruppen enthaltende dialkylether - Google Patents
Caroboxy- oder tetrazolengruppen enthaltende dialkyletherInfo
- Publication number
- ATE192732T1 ATE192732T1 AT96903794T AT96903794T ATE192732T1 AT E192732 T1 ATE192732 T1 AT E192732T1 AT 96903794 T AT96903794 T AT 96903794T AT 96903794 T AT96903794 T AT 96903794T AT E192732 T1 ATE192732 T1 AT E192732T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrazolene
- caroboxy
- dialkylethers
- groups
- noninsulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/28—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
- C07C47/37—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
- C07C59/315—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
- C07C59/353—Saturated compounds containing more than one carboxyl group containing keto groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/409,780 US5648387A (en) | 1995-03-24 | 1995-03-24 | Carboxyalkylethers, formulations, and treatment of vascular diseases |
PCT/US1996/001639 WO1996030328A1 (en) | 1995-03-24 | 1996-02-05 | Terminal carboxy or tetrazole groups containing dialkyl ethers |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE192732T1 true ATE192732T1 (de) | 2000-05-15 |
Family
ID=23621941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96903794T ATE192732T1 (de) | 1995-03-24 | 1996-02-05 | Caroboxy- oder tetrazolengruppen enthaltende dialkylether |
Country Status (27)
Country | Link |
---|---|
US (4) | US5648387A (de) |
EP (1) | EP0820428B1 (de) |
JP (1) | JP3885115B2 (de) |
KR (1) | KR100408612B1 (de) |
CN (1) | CN1100747C (de) |
AT (1) | ATE192732T1 (de) |
AU (1) | AU692359B2 (de) |
BG (1) | BG63534B1 (de) |
CA (1) | CA2215233C (de) |
CZ (1) | CZ289556B6 (de) |
DE (1) | DE69608268T2 (de) |
DK (1) | DK0820428T3 (de) |
EE (1) | EE03520B1 (de) |
ES (1) | ES2148733T3 (de) |
FI (1) | FI973713A (de) |
GR (1) | GR3034109T3 (de) |
HK (1) | HK1009438A1 (de) |
HU (1) | HUP9801825A3 (de) |
NO (1) | NO307878B1 (de) |
NZ (1) | NZ302170A (de) |
PL (1) | PL181673B1 (de) |
PT (1) | PT820428E (de) |
RU (1) | RU2191772C2 (de) |
SK (1) | SK282897B6 (de) |
UA (1) | UA46020C2 (de) |
WO (1) | WO1996030328A1 (de) |
ZA (1) | ZA962275B (de) |
Families Citing this family (79)
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IL119971A (en) * | 1997-01-07 | 2003-02-12 | Yissum Res Dev Co | Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids |
NZ503982A (en) * | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
US6861555B2 (en) * | 2000-01-25 | 2005-03-01 | Warner-Lambert Company | Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith |
KR20010033017A (ko) * | 1997-12-12 | 2001-04-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 과지질혈증 치료제인 스타틴-LP(a) 억제제의 병용 제제 |
SI1045691T1 (en) * | 1997-12-12 | 2005-04-30 | Warner-Lambert Company Llc | Statin-carboxyalkylether combinations |
US20030105154A1 (en) * | 2001-10-24 | 2003-06-05 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
ATE320803T1 (de) * | 1998-01-28 | 2006-04-15 | Warner Lambert Co | Verfahren zur behandlung von alzheimerschen krankheit |
HUP0103648A3 (en) * | 1998-09-30 | 2003-10-28 | Warner Lambert Co | Method for preventing or delaying catheter-based revascularization |
EP1849760A1 (de) * | 1999-04-01 | 2007-10-31 | Esperion Therapeutics Inc. | Ether-Verbindungen, Zusammensetzungen und ihre Verwendung |
CN1329359C (zh) | 1999-04-01 | 2007-08-01 | 埃斯佩里安医疗公司 | 醚化合物,及其组合物和用途 |
ATE431326T1 (de) | 2000-01-25 | 2009-05-15 | Warner Lambert Co | Calcium-dicarboxylatether, verfahren zu deren herstellung |
US20040092574A1 (en) * | 2000-02-07 | 2004-05-13 | Bisgaier Charles Larry | Statin-Lp(a) inhibitor combinations |
KR20020091245A (ko) * | 2000-04-26 | 2002-12-05 | 워너-램버트 캄파니 | 항고혈압제 및 용도 |
CA2414783A1 (en) * | 2000-07-14 | 2002-01-24 | Warner-Lambert Company | Treatment of eating disorders using carboxyalkylethers |
CN1479721A (zh) * | 2000-10-11 | 2004-03-03 | ͨ��ҽ�ƹ�˾ | 用于胆固醇治疗和相关应用的亚砜和双亚砜化合物和组合物 |
US7304093B2 (en) * | 2000-10-11 | 2007-12-04 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
JP2004529069A (ja) * | 2000-10-11 | 2004-09-24 | エスペリオン セラピューティクス,インコーポレイテッド | コレステロール管理用のエーテル化合物及び組成物ならびに関連する使用 |
BR0114619A (pt) | 2000-10-11 | 2005-12-13 | Esperion Therapeutics Inc | Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas |
AU1313602A (en) | 2000-10-11 | 2002-04-22 | Esperion Therapeutics Inc | Ketone compounds and compositions for cholesterol management and related uses |
US20040122091A1 (en) * | 2000-10-11 | 2004-06-24 | Esperion Therapeutics, Inc. | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
US20030225123A1 (en) * | 2001-03-22 | 2003-12-04 | Auerbach Bruce Jeffrey | Antihypertensive agents and use |
US20040072903A1 (en) * | 2001-05-08 | 2004-04-15 | Auerbach Bruce Jeffrey | Carboxyalkylether-acat inhibitors combinations |
US20040192771A1 (en) * | 2001-10-11 | 2004-09-30 | Dasseux Jean-Louis Henri | Ether compounds and compositions for cholesterol management and related uses |
US20040204502A1 (en) * | 2001-10-11 | 2004-10-14 | Dasseux Jean-Louis Henri | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
US20050020694A1 (en) * | 2001-10-11 | 2005-01-27 | Dasseux Jean-Louis Henri | Sulfide and disulfide compounds and compositions for cholesterol management and related uses |
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BE755997A (fr) * | 1969-09-11 | 1971-03-10 | Bp Chem Int Ltd | Production d'acides dicarboxyliques |
US3742068A (en) * | 1970-04-17 | 1973-06-26 | G Moersch | Ethers of 2,2,9,9-tetramethyl-1,10-decanediol |
IT1168389B (it) * | 1981-05-06 | 1987-05-20 | Alfa Farmaceutici Spa | Derivati di alcandioli con attivita' ipolipidemizzante,metodi per la loro preparazione e composizioni farmaceutiche che li contengono |
DE3423166A1 (de) * | 1984-06-22 | 1986-01-02 | Epis S.A., Zug | Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
IL84953A (en) * | 1987-12-28 | 1992-01-15 | Bromine Compounds Ltd | 3,3'-oxy-bis((2,2'-di(bromomethyl)propanoic acid)derivatives,processes for their preparation and their use as flame retardant agents |
DE3814498A1 (de) * | 1988-04-29 | 1989-11-09 | Basf Ag | Verfahren zur herstellung von hydroxicarbonsaeureestern |
US5395917A (en) * | 1993-05-21 | 1995-03-07 | E. I. Du Pont De Nemours And Company | Polyimides from 4-(3-aminophenoxy)benzoic acid |
-
1995
- 1995-03-24 US US08/409,780 patent/US5648387A/en not_active Expired - Lifetime
-
1996
- 1996-02-05 EE EE9700375A patent/EE03520B1/xx not_active IP Right Cessation
- 1996-02-05 NZ NZ302170A patent/NZ302170A/en unknown
- 1996-02-05 JP JP52934296A patent/JP3885115B2/ja not_active Expired - Lifetime
- 1996-02-05 AT AT96903794T patent/ATE192732T1/de not_active IP Right Cessation
- 1996-02-05 RU RU97118420/04A patent/RU2191772C2/ru not_active IP Right Cessation
- 1996-02-05 SK SK1286-97A patent/SK282897B6/sk unknown
- 1996-02-05 WO PCT/US1996/001639 patent/WO1996030328A1/en active IP Right Grant
- 1996-02-05 ES ES96903794T patent/ES2148733T3/es not_active Expired - Lifetime
- 1996-02-05 HU HU9801825A patent/HUP9801825A3/hu unknown
- 1996-02-05 CN CN96193500A patent/CN1100747C/zh not_active Expired - Fee Related
- 1996-02-05 DK DK96903794T patent/DK0820428T3/da active
- 1996-02-05 CZ CZ19972922A patent/CZ289556B6/cs not_active IP Right Cessation
- 1996-02-05 PT PT96903794T patent/PT820428E/pt unknown
- 1996-02-05 DE DE69608268T patent/DE69608268T2/de not_active Expired - Lifetime
- 1996-02-05 KR KR1019970706637A patent/KR100408612B1/ko not_active IP Right Cessation
- 1996-02-05 UA UA97105209A patent/UA46020C2/uk unknown
- 1996-02-05 EP EP96903794A patent/EP0820428B1/de not_active Expired - Lifetime
- 1996-02-05 PL PL96322407A patent/PL181673B1/pl not_active IP Right Cessation
- 1996-02-05 CA CA002215233A patent/CA2215233C/en not_active Expired - Fee Related
- 1996-02-05 AU AU47768/96A patent/AU692359B2/en not_active Ceased
- 1996-03-20 ZA ZA962275A patent/ZA962275B/xx unknown
-
1997
- 1997-02-25 US US08/806,582 patent/US5756544A/en not_active Expired - Lifetime
- 1997-02-25 US US08/806,580 patent/US5783600A/en not_active Expired - Lifetime
- 1997-02-25 US US08/805,533 patent/US5750569A/en not_active Expired - Lifetime
- 1997-09-17 FI FI973713A patent/FI973713A/fi not_active IP Right Cessation
- 1997-09-23 NO NO974397A patent/NO307878B1/no not_active IP Right Cessation
- 1997-10-24 BG BG101993A patent/BG63534B1/bg unknown
-
1998
- 1998-09-04 HK HK98110440A patent/HK1009438A1/xx not_active IP Right Cessation
-
2000
- 2000-08-02 GR GR20000401806T patent/GR3034109T3/el not_active IP Right Cessation
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UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |