ATE185146T1 - Verfahren zur entfernung von n-terminalem methionin - Google Patents
Verfahren zur entfernung von n-terminalem methioninInfo
- Publication number
- ATE185146T1 ATE185146T1 AT97303856T AT97303856T ATE185146T1 AT E185146 T1 ATE185146 T1 AT E185146T1 AT 97303856 T AT97303856 T AT 97303856T AT 97303856 T AT97303856 T AT 97303856T AT E185146 T1 ATE185146 T1 AT E185146T1
- Authority
- AT
- Austria
- Prior art keywords
- terminal
- removal
- terminal methionine
- methionine residue
- peptide
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical group CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title 1
- 229930182817 methionine Natural products 0.000 title 1
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/246—IL-2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- External Artificial Organs (AREA)
- Forging (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15463496 | 1996-06-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE185146T1 true ATE185146T1 (de) | 1999-10-15 |
Family
ID=15588495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97303856T ATE185146T1 (de) | 1996-06-14 | 1997-06-05 | Verfahren zur entfernung von n-terminalem methionin |
Country Status (11)
Country | Link |
---|---|
US (2) | US6066470A (de) |
EP (1) | EP0812856B1 (de) |
KR (1) | KR100478747B1 (de) |
CN (1) | CN1158303C (de) |
AT (1) | ATE185146T1 (de) |
CA (1) | CA2207723C (de) |
DE (1) | DE69700561T2 (de) |
DK (1) | DK0812856T3 (de) |
ES (1) | ES2136458T3 (de) |
GR (1) | GR3032139T3 (de) |
IL (1) | IL121053A (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2768743B1 (fr) * | 1997-09-23 | 2001-09-14 | Bio Merieux | Procede de lyse de micro-organisme |
AU6002199A (en) * | 1998-10-05 | 2000-04-26 | Takeda Chemical Industries Ltd. | Process for eliminating n-terminal methionine |
EP1138772A4 (de) * | 1998-12-11 | 2005-04-06 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von apelin |
AU2002221067A1 (en) * | 2000-12-07 | 2002-06-18 | Takeda Chemical Industries Ltd. | Process for producing rfrp |
EP1352964A4 (de) * | 2000-12-22 | 2005-02-16 | Nippon Soda Co | Verfahren zur herstellung einer substanz unter verwendung eines mikrobiellen katalysators |
EP2460530A3 (de) * | 2002-12-31 | 2012-08-29 | Althea Technologies, Inc. | Kristalle des menschlichen Wachstumshormons und Verfahren zu ihrer Herstellung |
DE10353973B4 (de) * | 2003-11-19 | 2006-08-17 | Beru Ag | Verfahren zum Herstellen eines keramischen Glühstiftes für eine keramische Glühkerze |
EP1976551A4 (de) * | 2005-12-23 | 2009-12-30 | Altus Pharmaceuticals Inc | Zusammensetzungen mit polykation-komplex-proteinkristallen und behandlungsverfahren damit |
JP5649825B2 (ja) | 2007-01-31 | 2015-01-07 | デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド | 安定化させたp53ペプチドおよびその使用法 |
KR20160061439A (ko) | 2007-03-28 | 2016-05-31 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
KR102104762B1 (ko) | 2010-08-13 | 2020-04-24 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
KR20140100937A (ko) | 2011-10-18 | 2014-08-18 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티도미메틱 거대고리 |
CN104144695A (zh) | 2012-02-15 | 2014-11-12 | 爱勒让治疗公司 | ***交联的和硫醚交联的拟肽大环化合物 |
CN107216380A (zh) | 2012-02-15 | 2017-09-29 | 爱勒让治疗公司 | 拟肽大环化合物 |
KR20150082307A (ko) | 2012-11-01 | 2015-07-15 | 에일러론 테라퓨틱스 인코포레이티드 | 이치환 아미노산 및 이의 제조 및 사용 방법 |
EA201690264A1 (ru) * | 2013-08-21 | 2016-06-30 | Кадила Хелзкэр Лимитед | Способ очистки pth |
BR112017005598A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e usos dos mesmos |
EP3294318A4 (de) | 2015-03-20 | 2019-04-03 | Aileron Therapeutics, Inc. | Peptidomimetische makrozyklen und verwendungen davon |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986007380A1 (en) | 1985-06-04 | 1986-12-18 | Takeda Chemical Industries, Ltd. | Process for preparing polypeptide |
IT1219454B (it) * | 1988-02-17 | 1990-05-18 | Serono Cesare Ist Ricerca | Metodo di rottura alla metionina di polipeptidi contenenti pontidisolfuro |
JPH06316557A (ja) * | 1993-03-06 | 1994-11-15 | Fuji Kagaku Kogyo Kk | アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤 |
-
1997
- 1997-06-05 AT AT97303856T patent/ATE185146T1/de not_active IP Right Cessation
- 1997-06-05 DK DK97303856T patent/DK0812856T3/da active
- 1997-06-05 EP EP97303856A patent/EP0812856B1/de not_active Expired - Lifetime
- 1997-06-05 DE DE69700561T patent/DE69700561T2/de not_active Expired - Lifetime
- 1997-06-05 ES ES97303856T patent/ES2136458T3/es not_active Expired - Lifetime
- 1997-06-10 US US08/872,417 patent/US6066470A/en not_active Expired - Lifetime
- 1997-06-10 IL IL12105397A patent/IL121053A/xx not_active IP Right Cessation
- 1997-06-13 KR KR1019970024663A patent/KR100478747B1/ko not_active IP Right Cessation
- 1997-06-13 CA CA002207723A patent/CA2207723C/en not_active Expired - Fee Related
- 1997-06-13 CN CNB971132569A patent/CN1158303C/zh not_active Expired - Fee Related
-
1999
- 1999-11-09 US US09/436,518 patent/US6309859B1/en not_active Expired - Fee Related
- 1999-12-15 GR GR990403225T patent/GR3032139T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2136458T3 (es) | 1999-11-16 |
IL121053A (en) | 2000-12-06 |
CA2207723A1 (en) | 1997-12-14 |
DK0812856T3 (da) | 2000-01-03 |
EP0812856B1 (de) | 1999-09-29 |
KR100478747B1 (ko) | 2005-09-08 |
EP0812856A1 (de) | 1997-12-17 |
KR980002062A (ko) | 1998-03-30 |
GR3032139T3 (en) | 2000-04-27 |
DE69700561D1 (de) | 1999-11-04 |
CN1158303C (zh) | 2004-07-21 |
DE69700561T2 (de) | 2000-05-04 |
US6066470A (en) | 2000-05-23 |
US6309859B1 (en) | 2001-10-30 |
CN1178798A (zh) | 1998-04-15 |
IL121053A0 (en) | 1997-11-20 |
CA2207723C (en) | 2006-12-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE185146T1 (de) | Verfahren zur entfernung von n-terminalem methionin | |
ATA193195A (de) | Verfahren zur gewinnung bzw. rückgewinnung von säuren aus metallhaltigen lösungen dieser säuren | |
DE59800221D1 (de) | Verfahren zur Stabilisierung von Retinol bzw. Retinol-Derivaten | |
DE69635076D1 (de) | Verfahren zur kontrollierung der sialylierung von durch säugetierzellkulturhergestellten protein | |
DE59905558D1 (de) | Verfahren zur überwachung von objekten bzw. eines objektraumes | |
DE69910557D1 (de) | Verfahren zur reinigung von aminonitrilen | |
DE69718027D1 (de) | Verfahren zur bekämpfung von unkräutern | |
DE59901861D1 (de) | Verfahren zur katalytischen zersetzung von n 2?o | |
DE69715234D1 (de) | Verfahren zur reinigung von 1,1-difluorethan | |
DE69714911D1 (de) | Verfahren zur Entfernung von Merkaptanen aus LNG | |
DE69017587D1 (de) | Verfahren zur Entfernung von Dimeren von Chloropren aus Polychloropren. | |
ATE220558T1 (de) | Verbessertes verfahren zur stabilisierung von proteinen | |
DE69935929D1 (de) | Verfahren zur reinigung von blutbestandteilen | |
DE69710078D1 (de) | Verfahren zur reinigung von 1,1,1,3,3-pentafluorpropan | |
ATA39595A (de) | Verfahren zur gewinnung bzw. rückgewinnung von säuren | |
DE59807142D1 (de) | Verfahren zur reinigung von anlagenteilen | |
DE69724207D1 (de) | Verfahren zur rückgewinnung von farben | |
DE59709984D1 (de) | Verfahren zur tränkung von bauteilen | |
DE69824283D1 (de) | Verfahren zur reinigung von caprolactam | |
DE69802435D1 (de) | Verfahren zur trennung von linearen internen olefinen von verzweigten internen olefinen | |
DE69809209D1 (de) | Verfahren zur rückgewinnung von fluorwasserstoff | |
ATE440857T1 (de) | Verfahren zum eliminieren von n-terminalem methionin | |
DE69418320D1 (de) | Verfahren zur rückgewinnung von fluorwasserstoff | |
DE69426837D1 (de) | Verfahren zur reinigung von 1,1,1,3,3-pentafluoro-2,3-dichloropropan | |
DE69732252D1 (de) | Verfahren zur Vakuumbedampfung von Metallen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |