ATE181106T1 - Mutationen in der 5'-3'-exonukleaseaktivität thermostabiler dna-polymerasen - Google Patents

Mutationen in der 5'-3'-exonukleaseaktivität thermostabiler dna-polymerasen

Info

Publication number
ATE181106T1
ATE181106T1 AT91919358T AT91919358T ATE181106T1 AT E181106 T1 ATE181106 T1 AT E181106T1 AT 91919358 T AT91919358 T AT 91919358T AT 91919358 T AT91919358 T AT 91919358T AT E181106 T1 ATE181106 T1 AT E181106T1
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AT
Austria
Prior art keywords
thermostable dna
sequence
seq
dna
dna polymerases
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Application number
AT91919358T
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English (en)
Inventor
David H Gelfand
Richard D Abramson
Original Assignee
Hoffmann La Roche
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Publication of ATE181106T1 publication Critical patent/ATE181106T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT91919358T 1990-09-28 1991-09-30 Mutationen in der 5'-3'-exonukleaseaktivität thermostabiler dna-polymerasen ATE181106T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US59049090A 1990-09-28 1990-09-28
US59021390A 1990-09-28 1990-09-28
US59046690A 1990-09-28 1990-09-28

Publications (1)

Publication Number Publication Date
ATE181106T1 true ATE181106T1 (de) 1999-06-15

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Family Applications (1)

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AT91919358T ATE181106T1 (de) 1990-09-28 1991-09-30 Mutationen in der 5'-3'-exonukleaseaktivität thermostabiler dna-polymerasen

Country Status (10)

Country Link
EP (2) EP0894860B1 (de)
JP (4) JP2709311B2 (de)
AT (1) ATE181106T1 (de)
AU (2) AU663474B2 (de)
CA (1) CA2090614C (de)
DE (1) DE69131321T2 (de)
DK (1) DK0550687T3 (de)
ES (1) ES2134198T3 (de)
GR (1) GR3031152T3 (de)
WO (1) WO1992006200A1 (de)

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JP3227101B2 (ja) 2001-11-12
AU663474B2 (en) 1995-10-12
AU4086896A (en) 1996-04-26
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GR3031152T3 (en) 1999-12-31
JP2709311B2 (ja) 1998-02-04
DK0550687T3 (da) 1999-12-13
JPH05506364A (ja) 1993-09-22
ES2134198T3 (es) 1999-10-01
AU691374B2 (en) 1998-05-14
CA2090614A1 (en) 1992-03-29
JP2886842B2 (ja) 1999-04-26
JP3227102B2 (ja) 2001-11-12
EP0894860B1 (de) 2012-12-12
CA2090614C (en) 2001-12-11
WO1992006200A1 (en) 1992-04-16
JPH104965A (ja) 1998-01-13
DE69131321D1 (de) 1999-07-15
JPH104985A (ja) 1998-01-13
EP0550687A1 (de) 1993-07-14
EP0894860A1 (de) 1999-02-03
AU8668891A (en) 1992-04-28
EP0550687B1 (de) 1999-06-09

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