ATE175113T1 - Verwendung von 4-amino-1-(2-pyridyl)piperidinen als 5-ht3-agonisten zur behandlung und verhütung von serotoninergen dysfunktionen - Google Patents

Verwendung von 4-amino-1-(2-pyridyl)piperidinen als 5-ht3-agonisten zur behandlung und verhütung von serotoninergen dysfunktionen

Info

Publication number
ATE175113T1
ATE175113T1 AT92400792T AT92400792T ATE175113T1 AT E175113 T1 ATE175113 T1 AT E175113T1 AT 92400792 T AT92400792 T AT 92400792T AT 92400792 T AT92400792 T AT 92400792T AT E175113 T1 ATE175113 T1 AT E175113T1
Authority
AT
Austria
Prior art keywords
serotoninergic
piperidines
pyridyl
amino
dysfunctions
Prior art date
Application number
AT92400792T
Other languages
English (en)
Inventor
Fur Gerard Le
Alberto Bianchetti
Antonina Giudice
Tiziano Croct
Philippe Soubrie
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9103735A external-priority patent/FR2674435B1/fr
Priority claimed from FR9110890A external-priority patent/FR2674752B1/fr
Application filed by Sanofi Sa filed Critical Sanofi Sa
Application granted granted Critical
Publication of ATE175113T1 publication Critical patent/ATE175113T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT92400792T 1991-03-27 1992-03-24 Verwendung von 4-amino-1-(2-pyridyl)piperidinen als 5-ht3-agonisten zur behandlung und verhütung von serotoninergen dysfunktionen ATE175113T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9103735A FR2674435B1 (fr) 1991-03-27 1991-03-27 Utilisation de 4-amino-1-(2-pyridyl) piperidines pour la preparation d'agents psychotropes.
FR9110890A FR2674752B1 (fr) 1991-09-03 1991-09-03 Utilisation de 4-amino-1-(2-pyridyl)piperidines pour la preparation de medicaments pour le traitement et la prophylaxie des etats decoulant d'un dysfonctionnement du systeme serotoninergique.
EP91402753 1991-10-15

Publications (1)

Publication Number Publication Date
ATE175113T1 true ATE175113T1 (de) 1999-01-15

Family

ID=27234263

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92400792T ATE175113T1 (de) 1991-03-27 1992-03-24 Verwendung von 4-amino-1-(2-pyridyl)piperidinen als 5-ht3-agonisten zur behandlung und verhütung von serotoninergen dysfunktionen

Country Status (9)

Country Link
US (1) US5604245A (de)
EP (1) EP0506545B1 (de)
JP (1) JP2603023B2 (de)
AT (1) ATE175113T1 (de)
AU (1) AU656563B2 (de)
CA (1) CA2063941A1 (de)
DE (1) DE69228017D1 (de)
HU (1) HUT61465A (de)
SG (1) SG47477A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0591030A3 (de) * 1992-09-25 1994-04-27 Sanofi 1-Heteroaryl-azetidine und -pyrrolidine als 5-HT3-Agoniste
CA2106840A1 (en) * 1992-09-25 1994-03-26 Marco Baroni Heteroarylazetidines and -pyrrolidines, process for their preparation and pharmaceutical compositions containing them
CA2133855A1 (en) * 1993-10-11 1995-04-12 Marco Baroni Heteroarylpiperidines, process for their preparation and pharmaceutical compositions in which they are present
EP0647639A1 (de) * 1993-10-11 1995-04-12 Sanofi Heteroarylpiperidinen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutischen Zusammenstellungen
US6833370B1 (en) * 1999-05-21 2004-12-21 Abbott Laboratories Heterocycle substituted aminoazacycles useful as central nervous system agents
ATE314058T1 (de) * 1999-11-23 2006-01-15 Janssen Pharmaceutica Nv Verwendung von 5ht3 antagonisten zur fundusentspannung
NZ520041A (en) 2000-01-20 2004-11-26 Eisai Co Ltd Novel piperidine compounds and drugs containing the same
US20040191312A1 (en) * 2002-12-31 2004-09-30 Donna Oksenberg 5-HT3 receptor agonists as neuroprotectors
CN111050800B (zh) * 2017-06-28 2023-04-04 国立大学法人大阪大学 血清素3受体激动剂对疼痛的治疗
JPWO2022118783A1 (de) * 2020-12-04 2022-06-09

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459240A1 (fr) * 1979-06-21 1981-01-09 Cm Ind Aminopiperidines anorexigenes, procede pour leur preparation, intermediaires dans ledit procede et medicaments qui les contiennent

Also Published As

Publication number Publication date
US5604245A (en) 1997-02-18
HU9200940D0 (en) 1992-05-28
EP0506545A3 (en) 1993-01-27
CA2063941A1 (en) 1992-09-28
AU656563B2 (en) 1995-02-09
JP2603023B2 (ja) 1997-04-23
DE69228017D1 (de) 1999-02-11
HUT61465A (en) 1993-01-28
EP0506545B1 (de) 1998-12-30
AU1316892A (en) 1992-10-01
SG47477A1 (en) 1998-04-17
JPH07145166A (ja) 1995-06-06
EP0506545A2 (de) 1992-09-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties