ATE173727T1 - Substituierte chinoline für die behandlung von leismaniosen - Google Patents

Substituierte chinoline für die behandlung von leismaniosen

Info

Publication number
ATE173727T1
ATE173727T1 AT92921565T AT92921565T ATE173727T1 AT E173727 T1 ATE173727 T1 AT E173727T1 AT 92921565 T AT92921565 T AT 92921565T AT 92921565 T AT92921565 T AT 92921565T AT E173727 T1 ATE173727 T1 AT E173727T1
Authority
AT
Austria
Prior art keywords
group
alkyl
alkenyl
phenyl
pct
Prior art date
Application number
AT92921565T
Other languages
English (en)
Inventor
Alain Fournet
Barrios Alcira Angelo
Victoria Munoz
Reynald Hocquemiller
Rue J-B-Clement Pharmacie
Francois Roblot
Jean Bruneton
Pascal Richomme
Jean Charles Gantier
Original Assignee
Orstom
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orstom filed Critical Orstom
Application granted granted Critical
Publication of ATE173727T1 publication Critical patent/ATE173727T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
AT92921565T 1991-10-03 1992-09-29 Substituierte chinoline für die behandlung von leismaniosen ATE173727T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9112174A FR2682107B1 (fr) 1991-10-03 1991-10-03 Quinoleines 2-substituees pour le traitement des leishmanioses.

Publications (1)

Publication Number Publication Date
ATE173727T1 true ATE173727T1 (de) 1998-12-15

Family

ID=9417546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92921565T ATE173727T1 (de) 1991-10-03 1992-09-29 Substituierte chinoline für die behandlung von leismaniosen

Country Status (10)

Country Link
US (1) US5541196A (de)
EP (1) EP0606380B1 (de)
JP (1) JP3728627B2 (de)
AT (1) ATE173727T1 (de)
DE (1) DE69227695D1 (de)
ES (1) ES2127762T3 (de)
FR (1) FR2682107B1 (de)
GR (1) GR3029471T3 (de)
OA (1) OA09930A (de)
WO (1) WO1993007125A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2819507B1 (fr) * 2001-01-17 2007-09-28 Inst Rech Developpement Ird Quinoleines substituees pour le traitement de co-infections a protozoaires et a retrovirus
US6673351B1 (en) 2001-03-16 2004-01-06 Astralis, Llc Compositions and methods for the treatment and clinical remission of psoriasis
US20040241168A1 (en) * 2001-03-16 2004-12-02 O'daly Jose A. Compositions and methods for the treatment and clinical remission of psoriasis
US9493419B2 (en) 2007-08-21 2016-11-15 The Hong Kong Polytechnic University Quinoline derivatives as anti-cancer agents
US9321730B2 (en) * 2007-08-21 2016-04-26 The Hong Kong Polytechnic University Method of making and administering quinoline derivatives as anti-cancer agents
FR2929943B1 (fr) 2008-04-15 2010-09-24 Inst Rech Developpement Ird Sels de quinoleines 2-substituees
FR2931479B1 (fr) * 2008-05-20 2012-12-07 I R D Nouveaux derives de quinoleines 2-substituees et un procede pour leur preparation
JP6283740B2 (ja) * 2013-10-10 2018-02-21 ルーヴァン・カトリック ユニバーシテイト キネトプラスチドによって惹起される疾病治療のための新規プラディミシン誘導体
WO2017103932A1 (en) * 2015-12-17 2017-06-22 Biokine Therapeutics Ltd. Small molecules for inhibiting chemokine activity, a kinase activity and/or cancer cells growth
WO2020206252A1 (en) * 2019-04-03 2020-10-08 University Of Central Florida Research Foundation, Inc. Antimalarial compounds
AU2020276793A1 (en) 2019-05-15 2022-01-20 Alonbio Ltd. Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death
CN110229101B (zh) * 2019-05-31 2020-11-03 浙江工业大学 用于检测黏度的aie荧光化合物及其制备与应用
AU2021211437A1 (en) * 2020-01-20 2022-09-15 Crescenta Biosciences Novel cell metabolism modulating compounds and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3636216A (en) * 1968-09-26 1972-01-18 Salsbury Lab Coccidiosis control with quinalinol derivatives
US4209519A (en) * 1978-03-13 1980-06-24 The United States Of America As Represented By The Secretary Of The Army Anti-leishmanial lepidine derivatives
GT198900005A (es) * 1988-01-29 1990-07-17 Quinolinas y cinolinas substituidas.

Also Published As

Publication number Publication date
JP3728627B2 (ja) 2005-12-21
FR2682107B1 (fr) 1995-04-21
GR3029471T3 (en) 1999-05-28
ES2127762T3 (es) 1999-05-01
WO1993007125A1 (fr) 1993-04-15
EP0606380B1 (de) 1998-11-25
US5541196A (en) 1996-07-30
EP0606380A1 (de) 1994-07-20
FR2682107A1 (fr) 1993-04-09
DE69227695D1 (de) 1999-01-07
OA09930A (fr) 1994-11-15
JPH07501048A (ja) 1995-02-02

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties