ATE170532T1 - PROSTAGLANDIN RECEPTOR FP AND CODING DNA - Google Patents

PROSTAGLANDIN RECEPTOR FP AND CODING DNA

Info

Publication number
ATE170532T1
ATE170532T1 AT94918699T AT94918699T ATE170532T1 AT E170532 T1 ATE170532 T1 AT E170532T1 AT 94918699 T AT94918699 T AT 94918699T AT 94918699 T AT94918699 T AT 94918699T AT E170532 T1 ATE170532 T1 AT E170532T1
Authority
AT
Austria
Prior art keywords
prostaglandin receptor
receptor
coding dna
host cells
dna encoding
Prior art date
Application number
AT94918699T
Other languages
German (de)
Inventor
Mark Abramovitz
Richard Grygorczyk
Kathleen Metters
Truyen Nguyen
Thomas H Rushmore
Deborah Slipetz
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Application granted granted Critical
Publication of ATE170532T1 publication Critical patent/ATE170532T1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • G01N33/686—Anti-idiotype
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A novel prostaglandin receptor has been identified and DNA encoding the receptor has been isolated, purified, sequenced and expressed in host cells. This DNA encoding the novel prostaglandin receptor and host cells expressing the receptor are used to identify modulators of the prostaglandin receptor.
AT94918699T 1993-06-25 1994-06-09 PROSTAGLANDIN RECEPTOR FP AND CODING DNA ATE170532T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/083,741 US5869281A (en) 1993-06-25 1993-06-25 DNA encoding prostaglandin receptor FP

Publications (1)

Publication Number Publication Date
ATE170532T1 true ATE170532T1 (en) 1998-09-15

Family

ID=22180389

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94918699T ATE170532T1 (en) 1993-06-25 1994-06-09 PROSTAGLANDIN RECEPTOR FP AND CODING DNA

Country Status (9)

Country Link
US (3) US5869281A (en)
EP (1) EP0705276B1 (en)
JP (1) JP3228751B2 (en)
AT (1) ATE170532T1 (en)
AU (1) AU6991894A (en)
CA (1) CA2165954C (en)
DE (1) DE69413039T2 (en)
ES (1) ES2120052T3 (en)
WO (1) WO1995000551A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202892D0 (en) 1992-10-02 1992-10-02 Kabi Pharmacia Ab DNA ENCODING A PROSTAGLANDIN RECEPTOR, A HOST CELL TRANSFORMED THEREWITH AND AN EXPRESSION PRODUCT THEREOF
US6057433A (en) * 1993-11-19 2000-05-02 Allergan Sales, Inc. Nucleic acid encoding human EP3 prostaglandin receptor
US6670134B1 (en) 1993-11-19 2003-12-30 Allergan, Inc. Human EP3 prostaglandin receptor
US7294331B2 (en) 1994-03-07 2007-11-13 Immunex Corporation Methods of using flt3-ligand in hematopoietic cell transplantation
WO1996023066A2 (en) * 1995-01-26 1996-08-01 Merck Frosst Canada Inc. Prostaglandin receptor, dp
US5955575A (en) * 1997-12-22 1999-09-21 Hopital Sainte-Justine Antagonists of G-protein-coupled receptor
CA2342960C (en) 1998-09-17 2010-03-09 Hopital Sainte-Justine G protein-coupled receptor antagonists
US6984719B1 (en) 1998-09-17 2006-01-10 Hospital Sainte-Justine Peptide antagonists of prostaglandin F2α receptor
AU9756898A (en) * 1998-11-12 2000-06-05 Gemini Genomics Ab Human prostaglandin receptors and methods of use thereof
WO2000051980A1 (en) 1999-03-05 2000-09-08 The Procter & Gamble Company C16 unsaturated fp-selective prostaglandins analogs
US6894175B1 (en) 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
AU784630B2 (en) 1999-12-06 2006-05-18 Hopital Sainte-Justine Compositions for treating abnormalities in glomerular filtration, patent ductus arteriosus and osteoporosis
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) * 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
DE60236951D1 (en) * 2001-05-21 2010-08-19 Fujifilm Corp Apparatus for carrying out biochemical analyzes and process for their preparation
US7521530B2 (en) 2002-06-11 2009-04-21 Universite De Montreal Peptides and peptidomimetics useful for inhibiting the activity of prostaglandin F2α receptor
WO2004073590A2 (en) * 2003-02-24 2004-09-02 Bayer Healthcare Ag Diagnostics and therapeutics for deseases associated with g-protein coupled receptor prostaglandin f2-alpha (prostaglandin f2-alpha)
US7320871B2 (en) * 2003-07-14 2008-01-22 Allergan, Inc. Human prostaglandin FP receptor variants and methods of using same
US20050074847A1 (en) * 2003-10-07 2005-04-07 Yanbin Liang Human prostaglandin EP1 receptor variants and methods of using same
US20050084929A1 (en) * 2003-10-17 2005-04-21 Yanbin Liang Human prostaglandin EP4 receptor variants and methods of using same
US20050084931A1 (en) * 2003-10-20 2005-04-21 Yanbin Liang Human prostaglandin DP receptor variants and methods of using same
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202892D0 (en) * 1992-10-02 1992-10-02 Kabi Pharmacia Ab DNA ENCODING A PROSTAGLANDIN RECEPTOR, A HOST CELL TRANSFORMED THEREWITH AND AN EXPRESSION PRODUCT THEREOF

Also Published As

Publication number Publication date
CA2165954A1 (en) 1995-01-05
EP0705276B1 (en) 1998-09-02
WO1995000551A1 (en) 1995-01-05
EP0705276A1 (en) 1996-04-10
US5840847A (en) 1998-11-24
ES2120052T3 (en) 1998-10-16
JPH11505701A (en) 1999-05-25
AU6991894A (en) 1995-01-17
CA2165954C (en) 2005-04-26
DE69413039D1 (en) 1998-10-08
DE69413039T2 (en) 1999-05-06
US5869281A (en) 1999-02-09
JP3228751B2 (en) 2001-11-12
US6358694B1 (en) 2002-03-19

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Legal Events

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