ATE169907T1 - Azaspiroalkan-derivate als therapeutika - Google Patents

Azaspiroalkan-derivate als therapeutika

Info

Publication number: ATE169907T1
Authority: AT; Austria
Prior art keywords: pct; optionally substituted; alkyl; phenyl; sec
Prior art date: 1992-11-09

Application number

AT93923549T

Other languages

English (en)

Inventor

Paul John Harris

Frank Kerrigan

Original Assignee

Knoll Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-09

Filing date

1993-10-23

Publication date

1998-09-15

1993-10-23 Application filed by Knoll Ag filed Critical Knoll Ag

1998-09-15 Application granted granted Critical

1998-09-15 Publication of ATE169907T1 publication Critical patent/ATE169907T1/de

Links

239000003814 drug Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
208000019901 Anxiety disease Diseases 0.000 abstract 1
208000019022 Mood disease Diseases 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 1
125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
230000036506 anxiety Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000001589 carboacyl group Chemical group 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000001624 naphthyl group Chemical group 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
-1 sulphamoyl Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents

AT93923549T 1992-11-09 1993-10-23 Azaspiroalkan-derivate als therapeutika ATE169907T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929223445A GB9223445D0 (en)	1992-11-09	1992-11-09	Therapeutic agents
CN94105852A CN1113911A (zh)	1992-11-09	1994-05-07	治疗剂

Publications (1)

Publication Number	Publication Date
ATE169907T1 true ATE169907T1 (de)	1998-09-15

Family

ID=37075771

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93923549T ATE169907T1 (de)	1992-11-09	1993-10-23	Azaspiroalkan-derivate als therapeutika

Country Status (27)

Country	Link
US (1)	US5610161A (de)
EP (1)	EP0667860B1 (de)
JP (1)	JPH08502985A (de)
CN (1)	CN1113911A (de)
AT (1)	ATE169907T1 (de)
AU (1)	AU5338194A (de)
BG (1)	BG99608A (de)
BR (1)	BR9307388A (de)
CA (1)	CA2148582A1 (de)
CZ (1)	CZ117595A3 (de)
DE (1)	DE69320488T2 (de)
DK (1)	DK0667860T3 (de)
ES (1)	ES2118977T3 (de)
FI (1)	FI952205A0 (de)
GB (1)	GB9223445D0 (de)
HR (1)	HRP931384A2 (de)
HU (2)	HUT71554A (de)
IL (1)	IL107486A0 (de)
IN (1)	IN176828B (de)
LT (1)	LT3421B (de)
MX (1)	MX9306951A (de)
NO (1)	NO951798L (de)
PL (1)	PL308754A1 (de)
SI (1)	SI9300584A (de)
SK (1)	SK58995A3 (de)
WO (1)	WO1994011346A1 (de)
ZA (1)	ZA938302B (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3218540A1 (de) *	1982-05-17	1983-11-24	Hoechst Ag, 6230 Frankfurt	Spiro-2-aza-alkan-3-carbonitrile, verfahren zu ihrer herstellung und ihre verwendung
US4430335A (en) *	1983-02-09	1984-02-07	Hoechst-Roussel Pharmaceuticals Inc.	Substituted 1-azaspiro[4,5]decanes and their analgesic compositions

1992
- 1992-11-09 GB GB929223445A patent/GB9223445D0/en active Pending
1993
- 1993-10-23 PL PL93308754A patent/PL308754A1/xx unknown
- 1993-10-23 CA CA002148582A patent/CA2148582A1/en not_active Abandoned
- 1993-10-23 AU AU53381/94A patent/AU5338194A/en not_active Abandoned
- 1993-10-23 HU HU9501317A patent/HUT71554A/hu unknown
- 1993-10-23 JP JP6511646A patent/JPH08502985A/ja active Pending
- 1993-10-23 US US08/424,388 patent/US5610161A/en not_active Expired - Fee Related
- 1993-10-23 SK SK589-95A patent/SK58995A3/sk unknown
- 1993-10-23 DK DK93923549T patent/DK0667860T3/da active
- 1993-10-23 ES ES93923549T patent/ES2118977T3/es not_active Expired - Lifetime
- 1993-10-23 WO PCT/EP1993/002951 patent/WO1994011346A1/en active IP Right Grant
- 1993-10-23 CZ CZ951175A patent/CZ117595A3/cs unknown
- 1993-10-23 EP EP93923549A patent/EP0667860B1/de not_active Expired - Lifetime
- 1993-10-23 AT AT93923549T patent/ATE169907T1/de not_active IP Right Cessation
- 1993-10-23 DE DE69320488T patent/DE69320488T2/de not_active Expired - Fee Related
- 1993-10-23 BR BR9307388-7A patent/BR9307388A/pt not_active Application Discontinuation
- 1993-10-28 IN IN696MA1993 patent/IN176828B/en unknown
- 1993-11-04 IL IL10748693A patent/IL107486A0/xx unknown
- 1993-11-08 ZA ZA938302A patent/ZA938302B/xx unknown
- 1993-11-08 MX MX9306951A patent/MX9306951A/es unknown
- 1993-11-09 HR HR931384A patent/HRP931384A2/hr not_active Application Discontinuation
- 1993-11-09 SI SI9300584A patent/SI9300584A/sl unknown
- 1993-11-09 LT LTIP1450A patent/LT3421B/lt not_active IP Right Cessation
1994
- 1994-05-07 CN CN94105852A patent/CN1113911A/zh active Pending
1995
- 1995-05-02 BG BG99608A patent/BG99608A/bg unknown
- 1995-05-08 FI FI952205A patent/FI952205A0/fi unknown
- 1995-05-08 NO NO951798A patent/NO951798L/no unknown
- 1995-06-30 HU HU95P/P00690P patent/HU211867A9/hu unknown

Also Published As

Publication number	Publication date
ES2118977T3 (es)	1998-10-01
CA2148582A1 (en)	1994-05-26
AU5338194A (en)	1994-06-08
JPH08502985A (ja)	1996-04-02
PL308754A1 (en)	1995-08-21
DE69320488D1 (de)	1998-09-24
IL107486A0 (en)	1994-02-27
LTIP1450A (en)	1994-10-25
FI952205A (fi)	1995-05-08
NO951798D0 (no)	1995-05-08
US5610161A (en)	1997-03-11
EP0667860A1 (de)	1995-08-23
BR9307388A (pt)	1999-08-31
MX9306951A (es)	1995-01-31
ZA938302B (en)	1994-05-09
CN1113911A (zh)	1995-12-27
SI9300584A (en)	1994-06-30
WO1994011346A1 (en)	1994-05-26
CZ117595A3 (en)	1995-12-13
IN176828B (de)	1996-09-21
FI952205A0 (fi)	1995-05-08
NO951798L (no)	1995-05-31
EP0667860B1 (de)	1998-08-19
HUT71554A (en)	1995-12-28
HRP931384A2 (en)	1994-12-31
SK58995A3 (en)	1995-10-11
DE69320488T2 (de)	1998-12-24
DK0667860T3 (da)	1999-05-25
LT3421B (en)	1995-09-25
BG99608A (bg)	1995-08-28
HU9501317D0 (en)	1995-06-28
HU211867A9 (en)	1995-12-28
GB9223445D0 (en)	1992-12-23

Legal Events

Date	Code	Title	Description
1999-02-15	UEP	Publication of translation of european patent specification
2003-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
GB9524157D0 (en)	1996-01-24	Therapeutic agents
KR960701055A (ko)	1996-02-24	인터로이킨-1 및 종양 괴사 인자 억제 활성을 지닌 피라졸로트리아진 (pyrazol itriazines with interleukin-1 and tumour necrosis factor in-hibitory actvity)
NO951797L (no)	1995-05-24	Terapeutiske midler
DE69231445D1 (de)	2000-10-19	Triazole enthaltende antifungizide mittel
FI945581A (fi)	1994-11-28	Substituoidut (aryylialkoksibentsyyli) aminopropaaniamidijohdannaiset, niiden valmistus ja käyttö antiepileptisinä, neuroprotektiivisina ja antidepressiivisinä aineina
DE59304311D1 (de)	1996-11-28	N-substituierte 3-azabicyclo[3.2.0]heptan-derivate als neuroleptika
ATE169907T1 (de)	1998-09-15	Azaspiroalkan-derivate als therapeutika
DE69416311D1 (de)	1999-03-11	Verwendung von cephem-derivaten als antimetastatische mittel
JO1785B1 (en)	1994-12-25	Therapeutic agents
DE59304826D1 (de)	1997-01-30	Substituierte 3-azabicyclo[3.2.0]heptan-derivate als zwischenprodukte
ZA93969B (en)	1994-08-12	Mixture of optically active cyclohexenone oxime ethers their preparation intermediates for this purpose and their use as herbicides