ATE169018T1 - Tetracyclische derivate, verfahren zu ihrer herstellung und ihre verwendung - Google Patents

Tetracyclische derivate, verfahren zu ihrer herstellung und ihre verwendung

Info

Publication number
ATE169018T1
ATE169018T1 AT95907565T AT95907565T ATE169018T1 AT E169018 T1 ATE169018 T1 AT E169018T1 AT 95907565 T AT95907565 T AT 95907565T AT 95907565 T AT95907565 T AT 95907565T AT E169018 T1 ATE169018 T1 AT E169018T1
Authority
AT
Austria
Prior art keywords
production
tetracyclic derivatives
tetracyclic
derivatives
Prior art date
Application number
AT95907565T
Other languages
English (en)
Inventor
Alain Claude-Marie Daugan
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10749089&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE169018(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE169018T1 publication Critical patent/ATE169018T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT95907565T 1994-01-21 1995-01-19 Tetracyclische derivate, verfahren zu ihrer herstellung und ihre verwendung ATE169018T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9401090A GB9401090D0 (en) 1994-01-21 1994-01-21 Chemical compounds

Publications (1)

Publication Number Publication Date
ATE169018T1 true ATE169018T1 (de) 1998-08-15

Family

ID=10749089

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95907565T ATE169018T1 (de) 1994-01-21 1995-01-19 Tetracyclische derivate, verfahren zu ihrer herstellung und ihre verwendung

Country Status (49)

Country Link
US (5) US5859006A (de)
EP (1) EP0740668B1 (de)
JP (3) JP3808095B2 (de)
KR (1) KR100357411B1 (de)
CN (2) CN1045777C (de)
AP (1) AP556A (de)
AT (1) ATE169018T1 (de)
AU (2) AU689205B2 (de)
BG (1) BG62733B1 (de)
BR (1) BR9506559C8 (de)
CA (1) CA2181377C (de)
CO (1) CO4340684A1 (de)
CZ (1) CZ286566B6 (de)
DE (2) DE10399006I2 (de)
DK (1) DK0740668T3 (de)
EE (1) EE03231B1 (de)
EG (1) EG25852A (de)
ES (1) ES2122543T3 (de)
FI (1) FI113176B (de)
GB (1) GB9401090D0 (de)
HK (1) HK1013286A1 (de)
HR (1) HRP950023B1 (de)
HU (1) HU222494B1 (de)
IL (1) IL112384A (de)
IN (1) IN183942B (de)
IS (1) IS1888B (de)
LU (1) LU91017I2 (de)
LV (1) LV11690B (de)
MA (1) MA23433A1 (de)
MX (1) MX9602904A (de)
MY (1) MY114663A (de)
NL (1) NL300124I2 (de)
NO (2) NO306465B1 (de)
NZ (1) NZ279199A (de)
OA (1) OA10584A (de)
PE (1) PE49495A1 (de)
PL (1) PL179744B1 (de)
RO (1) RO117794B1 (de)
RU (1) RU2142463C1 (de)
SA (1) SA95150475B1 (de)
SG (1) SG49184A1 (de)
SI (1) SI0740668T1 (de)
SK (1) SK280879B6 (de)
SV (1) SV1995000002A (de)
TN (1) TNSN95004A1 (de)
TW (1) TW378210B (de)
UY (1) UY23893A1 (de)
WO (1) WO1995019978A1 (de)
ZA (1) ZA95424B (de)

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EG25852A (en) 2012-09-10
CN1143963A (zh) 1997-02-26
PE49495A1 (es) 1996-01-10
NZ279199A (en) 1998-01-26
SI0740668T1 (en) 1999-02-28
JP2004217674A (ja) 2004-08-05
KR100357411B1 (ko) 2003-02-05
CA2181377C (en) 2002-05-28
BR9506559A (pt) 1997-10-28
IL112384A (en) 1998-08-16
AU707055B2 (en) 1999-07-01
CO4340684A1 (es) 1996-07-30
PL315559A1 (en) 1996-11-12
CN1045777C (zh) 1999-10-20
DE10399006I2 (de) 2004-05-06
ZA95424B (en) 1995-09-27
GB9401090D0 (en) 1994-03-16
NL300124I1 (nl) 2003-07-01
UY23893A1 (es) 1995-07-11
IN183942B (de) 2000-05-20
CA2181377A1 (en) 1995-07-27
IS1888B (is) 2003-09-01
PL179744B1 (pl) 2000-10-31
US20020119976A1 (en) 2002-08-29
US6025494A (en) 2000-02-15
DE69503753D1 (de) 1998-09-03
US6369059B1 (en) 2002-04-09
HK1013286A1 (en) 1999-08-20
US6784179B2 (en) 2004-08-31
AP556A (en) 1996-11-07
IL112384A0 (en) 1995-03-30
JP3808095B2 (ja) 2006-08-09
FI962927A (fi) 1996-07-19
CN1070492C (zh) 2001-09-05
ES2122543T3 (es) 1998-12-16
HU222494B1 (hu) 2003-07-28
NO306465B1 (no) 1999-11-08

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