ATE147749T1 - Verfahren zur herstellung von azt(3'-azido-3'- desoxythymidin) und diebezüglichen verbindungen - Google Patents
Verfahren zur herstellung von azt(3'-azido-3'- desoxythymidin) und diebezüglichen verbindungenInfo
- Publication number
- ATE147749T1 ATE147749T1 AT90403010T AT90403010T ATE147749T1 AT E147749 T1 ATE147749 T1 AT E147749T1 AT 90403010 T AT90403010 T AT 90403010T AT 90403010 T AT90403010 T AT 90403010T AT E147749 T1 ATE147749 T1 AT E147749T1
- Authority
- AT
- Austria
- Prior art keywords
- deoxythymidine
- azt
- azido
- producing
- related compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8914132A FR2653771B1 (fr) | 1989-10-27 | 1989-10-27 | Procede de preparation de l'azt (azido-3'-desoxy-3'-thymidine) et de composes apparentes. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE147749T1 true ATE147749T1 (de) | 1997-02-15 |
Family
ID=9386862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90403010T ATE147749T1 (de) | 1989-10-27 | 1990-10-25 | Verfahren zur herstellung von azt(3'-azido-3'- desoxythymidin) und diebezüglichen verbindungen |
Country Status (8)
Country | Link |
---|---|
US (1) | US5124442A (de) |
EP (1) | EP0427587B1 (de) |
JP (1) | JPH03209393A (de) |
KR (1) | KR910007919A (de) |
AT (1) | ATE147749T1 (de) |
CA (1) | CA2028648A1 (de) |
DE (1) | DE69029708D1 (de) |
FR (1) | FR2653771B1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5545629A (en) * | 1994-04-12 | 1996-08-13 | Montefiore Medical Center | 5-ethoxy-2'-deoxyuridines |
WO2000075154A2 (en) * | 1999-06-04 | 2000-12-14 | Alliedsignal Inc. | Protected nucleosides |
CN101190934B (zh) * | 2006-11-27 | 2010-12-15 | 上海迪赛诺化学制药有限公司 | 相转移法制备齐多夫定叠氮中间体的方法 |
CN101376667B (zh) * | 2007-08-27 | 2011-01-12 | 上海迪赛诺医药发展有限公司 | 一种合成齐多夫定的中间体及其制备方法和该中间体在合成齐多夫定中的应用 |
WO2013067669A1 (zh) * | 2011-11-07 | 2013-05-16 | 上海迪赛诺药业有限公司 | 制备齐多夫定及其中间体的方法 |
CN103443095B (zh) * | 2011-11-07 | 2016-01-20 | 上海迪赛诺药业有限公司 | 制备齐多夫定及其中间体的方法 |
CN103864870A (zh) * | 2013-11-28 | 2014-06-18 | 安徽一帆香料有限公司 | 一种齐多夫定的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5914040B2 (ja) * | 1976-04-05 | 1984-04-02 | ヤマサ醤油株式会社 | O↑2,3′−サイクロピリミジンヌクレオシド類の製造法 |
CA1285935C (en) * | 1985-03-16 | 1991-07-09 | Janet Lister Rideout | Therapeutic nucleosides |
US4916122A (en) * | 1987-01-28 | 1990-04-10 | University Of Georgia Research Foundation, Inc. | 3'-Azido-2',3'-dideoxyuridine anti-retroviral composition |
US4681933A (en) * | 1986-05-01 | 1987-07-21 | University Of Georgia Research Foundation, Inc. | 2',3'-dideoxy-5-substituted uridines and related compounds as antiviral agents |
CA1327801C (en) * | 1986-07-09 | 1994-03-15 | Kenji Arai | Cyclohexane herbicides |
FR2640267B2 (fr) * | 1988-01-19 | 1992-02-14 | Univ Paris Curie | Procede de synthese de l'azido-3(prime)-desoxy-3(prime)-thymidine et analogues |
-
1989
- 1989-10-27 FR FR8914132A patent/FR2653771B1/fr not_active Expired - Fee Related
-
1990
- 1990-10-25 DE DE69029708T patent/DE69029708D1/de not_active Expired - Lifetime
- 1990-10-25 EP EP90403010A patent/EP0427587B1/de not_active Expired - Lifetime
- 1990-10-25 AT AT90403010T patent/ATE147749T1/de not_active IP Right Cessation
- 1990-10-25 US US07/603,010 patent/US5124442A/en not_active Expired - Fee Related
- 1990-10-26 KR KR1019900017263A patent/KR910007919A/ko active IP Right Grant
- 1990-10-26 CA CA002028648A patent/CA2028648A1/fr not_active Abandoned
- 1990-10-29 JP JP2291669A patent/JPH03209393A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2028648A1 (fr) | 1991-04-28 |
JPH03209393A (ja) | 1991-09-12 |
DE69029708D1 (de) | 1997-02-27 |
FR2653771A1 (fr) | 1991-05-03 |
EP0427587A1 (de) | 1991-05-15 |
US5124442A (en) | 1992-06-23 |
FR2653771B1 (fr) | 1994-09-23 |
KR910007919A (ko) | 1991-05-30 |
EP0427587B1 (de) | 1997-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |