ATE128456T1 - METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL. - Google Patents

METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL.

Info

Publication number
ATE128456T1
ATE128456T1 AT92202911T AT92202911T ATE128456T1 AT E128456 T1 ATE128456 T1 AT E128456T1 AT 92202911 T AT92202911 T AT 92202911T AT 92202911 T AT92202911 T AT 92202911T AT E128456 T1 ATE128456 T1 AT E128456T1
Authority
AT
Austria
Prior art keywords
amino alcohol
alpha
producing
alcohol
amino
Prior art date
Application number
AT92202911T
Other languages
German (de)
Inventor
Wilhelmus Hubertus Jos Boesten
Harold Monro Moody
Quirinus Bernardus Broxterman
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Application granted granted Critical
Publication of ATE128456T1 publication Critical patent/ATE128456T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to a method for the preparation of an a,a-disubstituted a-amino alcohol from the corresponding amide with the aid of sodium in the presence of an alcohol as solvent. The conversion of amino acid amide to amino alcohol proceeds virtually quantitatively. Moreover, the reduction of the amino acid amide to the corresponding amino alcohol proceeds with retention of optical activity.
AT92202911T 1991-09-26 1992-09-22 METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL. ATE128456T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9101623A NL9101623A (en) 1991-09-26 1991-09-26 PROCESS FOR PREPARING AN ALCOHOL.

Publications (1)

Publication Number Publication Date
ATE128456T1 true ATE128456T1 (en) 1995-10-15

Family

ID=19859747

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92202911T ATE128456T1 (en) 1991-09-26 1992-09-22 METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL.

Country Status (6)

Country Link
US (1) US5276190A (en)
EP (1) EP0534553B1 (en)
JP (1) JPH05201936A (en)
AT (1) ATE128456T1 (en)
DE (1) DE69205107T2 (en)
NL (1) NL9101623A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399763A (en) * 1993-02-01 1995-03-21 Nippon Kayaku Kabushiki Kaisha Process for preparing optically active 2-aminopropanal
PT778263E (en) * 1994-08-22 2002-06-28 Mitsubishi Pharma Corp COMPOSITION OF BENZENE AND ITS PHARMACEUTICAL UTILIZATION
US5948820A (en) 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
KR100836547B1 (en) 2002-01-11 2008-06-10 상꾜 가부시키가이샤 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US7910617B2 (en) 2004-02-24 2011-03-22 Sankyo Company, Limited Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound
CN110054538B (en) * 2018-01-19 2021-02-09 中国农业大学 Method for reducing tertiary amide into amine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2618658A (en) * 1949-06-08 1952-11-18 Eastman Kodak Co 2,2-dimethyl-3-hydroxypropylamine and process for its preparation
JPH0653161B2 (en) * 1988-09-28 1994-07-20 東洋紡績株式会社 Circulator

Also Published As

Publication number Publication date
DE69205107T2 (en) 1996-05-09
DE69205107D1 (en) 1995-11-02
NL9101623A (en) 1993-04-16
EP0534553A1 (en) 1993-03-31
EP0534553B1 (en) 1995-09-27
JPH05201936A (en) 1993-08-10
US5276190A (en) 1994-01-04

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Legal Events

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