ATE128456T1 - METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL. - Google Patents
METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL.Info
- Publication number
- ATE128456T1 ATE128456T1 AT92202911T AT92202911T ATE128456T1 AT E128456 T1 ATE128456 T1 AT E128456T1 AT 92202911 T AT92202911 T AT 92202911T AT 92202911 T AT92202911 T AT 92202911T AT E128456 T1 ATE128456 T1 AT E128456T1
- Authority
- AT
- Austria
- Prior art keywords
- amino alcohol
- alpha
- producing
- alcohol
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to a method for the preparation of an a,a-disubstituted a-amino alcohol from the corresponding amide with the aid of sodium in the presence of an alcohol as solvent. The conversion of amino acid amide to amino alcohol proceeds virtually quantitatively. Moreover, the reduction of the amino acid amide to the corresponding amino alcohol proceeds with retention of optical activity.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL9101623A NL9101623A (en) | 1991-09-26 | 1991-09-26 | PROCESS FOR PREPARING AN ALCOHOL. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE128456T1 true ATE128456T1 (en) | 1995-10-15 |
Family
ID=19859747
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92202911T ATE128456T1 (en) | 1991-09-26 | 1992-09-22 | METHOD FOR PRODUCING AN ALPHA-AMINO ALCOHOL. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5276190A (en) |
EP (1) | EP0534553B1 (en) |
JP (1) | JPH05201936A (en) |
AT (1) | ATE128456T1 (en) |
DE (1) | DE69205107T2 (en) |
NL (1) | NL9101623A (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5399763A (en) * | 1993-02-01 | 1995-03-21 | Nippon Kayaku Kabushiki Kaisha | Process for preparing optically active 2-aminopropanal |
PT778263E (en) * | 1994-08-22 | 2002-06-28 | Mitsubishi Pharma Corp | COMPOSITION OF BENZENE AND ITS PHARMACEUTICAL UTILIZATION |
US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
KR100836547B1 (en) | 2002-01-11 | 2008-06-10 | 상꾜 가부시키가이샤 | Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these |
US7910617B2 (en) | 2004-02-24 | 2011-03-22 | Sankyo Company, Limited | Method for suppressing the number of peripheral blood lymphocytes using an amino alcohol compound |
CN110054538B (en) * | 2018-01-19 | 2021-02-09 | 中国农业大学 | Method for reducing tertiary amide into amine |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2618658A (en) * | 1949-06-08 | 1952-11-18 | Eastman Kodak Co | 2,2-dimethyl-3-hydroxypropylamine and process for its preparation |
JPH0653161B2 (en) * | 1988-09-28 | 1994-07-20 | 東洋紡績株式会社 | Circulator |
-
1991
- 1991-09-26 NL NL9101623A patent/NL9101623A/en not_active Application Discontinuation
-
1992
- 1992-09-22 DE DE69205107T patent/DE69205107T2/en not_active Expired - Fee Related
- 1992-09-22 AT AT92202911T patent/ATE128456T1/en not_active IP Right Cessation
- 1992-09-22 EP EP92202911A patent/EP0534553B1/en not_active Expired - Lifetime
- 1992-09-22 JP JP4252676A patent/JPH05201936A/en active Pending
- 1992-09-25 US US07/950,713 patent/US5276190A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69205107T2 (en) | 1996-05-09 |
DE69205107D1 (en) | 1995-11-02 |
NL9101623A (en) | 1993-04-16 |
EP0534553A1 (en) | 1993-03-31 |
EP0534553B1 (en) | 1995-09-27 |
JPH05201936A (en) | 1993-08-10 |
US5276190A (en) | 1994-01-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |