ATE12485T1 - Salze der valproinsaeure, ihre herstellung und ihre verwendung. - Google Patents

Salze der valproinsaeure, ihre herstellung und ihre verwendung.

Info

Publication number
ATE12485T1
ATE12485T1 AT82870062T AT82870062T ATE12485T1 AT E12485 T1 ATE12485 T1 AT E12485T1 AT 82870062 T AT82870062 T AT 82870062T AT 82870062 T AT82870062 T AT 82870062T AT E12485 T1 ATE12485 T1 AT E12485T1
Authority
AT
Austria
Prior art keywords
valproic acid
salts
preparation
acid
valproic
Prior art date
Application number
AT82870062T
Other languages
English (en)
Inventor
Arthur Marie Deboeck
Original Assignee
Pharlyse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharlyse filed Critical Pharlyse
Application granted granted Critical
Publication of ATE12485T1 publication Critical patent/ATE12485T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/126—Acids containing more than four carbon atoms
    • C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT82870062T 1981-11-04 1982-11-03 Salze der valproinsaeure, ihre herstellung und ihre verwendung. ATE12485T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU83729A LU83729A1 (fr) 1981-11-04 1981-11-04 Sels d'acide valproique,leur preparation et leur utilisation
EP82870062A EP0078785B1 (de) 1981-11-04 1982-11-03 Salze der Valproinsäure, ihre Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
ATE12485T1 true ATE12485T1 (de) 1985-04-15

Family

ID=19729754

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82870062T ATE12485T1 (de) 1981-11-04 1982-11-03 Salze der valproinsaeure, ihre herstellung und ihre verwendung.

Country Status (5)

Country Link
US (1) US4699927A (de)
EP (1) EP0078785B1 (de)
AT (1) ATE12485T1 (de)
DE (1) DE3262899D1 (de)
LU (1) LU83729A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5185159A (en) * 1983-07-20 1993-02-09 Sanofi Pharmaceutical composition based on valproic acid and a process for preparing it
IL72381A (en) * 1983-07-20 1988-03-31 Sanofi Sa Pharmaceutical composition based on valproic acid
US4913906B1 (en) * 1985-02-28 2000-06-06 Yissum Res Dev Co Controlled release dosage form of valproic acid
FR2587900B1 (fr) * 1985-10-01 1988-10-07 Morelle Jean Associations acides gras-acides amines basiques, douees de proprietes emollientes, emulsifiantes et antioxydantes, destinees a la cosmetique, la dermatologie et l'alimentation
IT1233836B (it) * 1988-01-13 1992-04-21 Euroresearch Srl Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato.
US20020025341A1 (en) * 1998-12-18 2002-02-28 Yihong Qiu Controlled release formulation of divalproex sodium
US20020031549A1 (en) * 1998-12-18 2002-03-14 Yihong Qiu Controlled release formulation of divalproex sodium
US6419953B1 (en) * 1998-12-18 2002-07-16 Abbott Laboratories Controlled release formulation of divalproex sodium
US6528090B2 (en) 1998-12-18 2003-03-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6511678B2 (en) 1998-12-18 2003-01-28 Abbott Laboratories Controlled release formulation of divalproex sodium
US6713086B2 (en) 1998-12-18 2004-03-30 Abbott Laboratories Controlled release formulation of divalproex sodium
HUP0600526A2 (en) * 2000-07-21 2006-11-28 Teva Pharma Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder
ATE301995T1 (de) * 2000-08-17 2005-09-15 Teva Pharma Verwendung von derivaten der valproinsäureamide und 2-valproinsäureamid zur behandlung und prävention von schmerzen und/oder kopfschmerzen
JP3825246B2 (ja) * 2000-11-24 2006-09-27 Ｎｅｃエレクトロニクス株式会社 化学的機械的研磨用スラリー
WO2002051402A1 (en) * 2000-12-22 2002-07-04 Abbott Laboratories Controlled release formulation of divalproex sodium
US6610326B2 (en) 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
WO2004071424A2 (en) * 2003-02-05 2004-08-26 Teva Pharmaceutical Industries, Ltd. Immediate release formulation of n-(2-propylpentanoyl)glycinamide
EP1626707A4 (de) * 2003-02-05 2009-07-01 Yissum Res Dev Co Formulierung von n-(2-propylpentanoyl)-glycinamid mit verzögerter freisetzung und verwandten verbindungen
CA2525366A1 (en) 2003-05-16 2004-11-25 Pfizer Products Inc. Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines
CN1309760C (zh) * 2003-10-16 2007-04-11 北京北医投资管理有限公司医药科技开发分公司 聚天冬酰甘氨酸、丙氨酸和赖氨酸及其制备方法和医药用途
CA2567249A1 (en) * 2004-04-19 2006-10-05 Jds Pharmaceuticals, Llc Lithium combinations, and uses related thereto
US7713550B2 (en) * 2004-06-15 2010-05-11 Andrx Corporation Controlled release sodium valproate formulation
US20050276849A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release dosage forms
US20050276848A1 (en) * 2004-06-15 2005-12-15 Nilobon Podhipleux Sustained release neutralized divalproex sodium
AU2006282896A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258358A3 (de) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenese mit Acetylcholinesterasehemmer
CA2623745A1 (en) * 2005-09-23 2007-04-05 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
US8378117B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
US7790718B2 (en) * 2005-09-23 2010-09-07 Janssen Pharmaceutica Nv Tetrahydro-cyclopentyl pyrazole cannabinoid modulators
DE602006012514D1 (de) * 2005-09-23 2010-04-08 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl-pyrazol-cannabinoid-modulatoren
US7825151B2 (en) * 2005-09-23 2010-11-02 Janssen Pharmaceutica Nv Hexahydro-cyclooctyl pyrazole cannabinoid modulators
US8378096B2 (en) * 2005-09-23 2013-02-19 Janssen Pharmaceutica N.V. Hexahydro-cycloheptapyrazole cannabinoid modulators
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
CA2625210A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20070117858A1 (en) * 2005-11-23 2007-05-24 Mingde Xia Substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulators
EP1979593B1 (de) * 2006-02-03 2017-12-06 Rolls-Royce Corporation Gasturbinenantriebsstoffsystem mit treibstoffmessendem ventil
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
US8012957B2 (en) * 2006-03-27 2011-09-06 Janssen Pharmaceutica Nv Tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulators
US20070254911A1 (en) * 2006-03-27 2007-11-01 Mingde Xia Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
US7678808B2 (en) 2006-05-09 2010-03-16 Braincells, Inc. 5 HT receptor mediated neurogenesis
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス，インコーポレイティド ４−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US7943653B2 (en) * 2007-08-13 2011-05-17 Janssen Pharmaceutica N.V. Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
WO2016067297A1 (en) * 2014-10-27 2016-05-06 Cellix Bio Private Limited Salts of valproic acid with piperazine, ethylenediamine, lysine and/or eicosapentaenoic ecid (epa) amine derivatives for the treatment of epilepsy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662046A (en) * 1948-06-19 1953-12-08 Merck & Co Inc Parenteral amino acid solution
US3024272A (en) * 1958-04-22 1962-03-06 Du Pont Organic acid salts of basic amino acids and their use
FR2442M (fr) * 1962-10-17 1964-04-06 Henry Eugene L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central.

Also Published As

Publication number Publication date
LU83729A1 (fr) 1983-09-01
EP0078785A1 (de) 1983-05-11
US4699927A (en) 1987-10-13
EP0078785B1 (de) 1985-04-03
DE3262899D1 (en) 1985-05-09

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