ATE12485T1 - Salze der valproinsaeure, ihre herstellung und ihre verwendung. - Google Patents
Salze der valproinsaeure, ihre herstellung und ihre verwendung.Info
- Publication number
- ATE12485T1 ATE12485T1 AT82870062T AT82870062T ATE12485T1 AT E12485 T1 ATE12485 T1 AT E12485T1 AT 82870062 T AT82870062 T AT 82870062T AT 82870062 T AT82870062 T AT 82870062T AT E12485 T1 ATE12485 T1 AT E12485T1
- Authority
- AT
- Austria
- Prior art keywords
- valproic acid
- salts
- preparation
- acid
- valproic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
- C07C53/128—Acids containing more than four carbon atoms the carboxylic group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU83729A LU83729A1 (fr) | 1981-11-04 | 1981-11-04 | Sels d'acide valproique,leur preparation et leur utilisation |
EP82870062A EP0078785B1 (de) | 1981-11-04 | 1982-11-03 | Salze der Valproinsäure, ihre Herstellung und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE12485T1 true ATE12485T1 (de) | 1985-04-15 |
Family
ID=19729754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT82870062T ATE12485T1 (de) | 1981-11-04 | 1982-11-03 | Salze der valproinsaeure, ihre herstellung und ihre verwendung. |
Country Status (5)
Country | Link |
---|---|
US (1) | US4699927A (de) |
EP (1) | EP0078785B1 (de) |
AT (1) | ATE12485T1 (de) |
DE (1) | DE3262899D1 (de) |
LU (1) | LU83729A1 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5185159A (en) * | 1983-07-20 | 1993-02-09 | Sanofi | Pharmaceutical composition based on valproic acid and a process for preparing it |
IL72381A (en) * | 1983-07-20 | 1988-03-31 | Sanofi Sa | Pharmaceutical composition based on valproic acid |
US4913906B1 (en) * | 1985-02-28 | 2000-06-06 | Yissum Res Dev Co | Controlled release dosage form of valproic acid |
FR2587900B1 (fr) * | 1985-10-01 | 1988-10-07 | Morelle Jean | Associations acides gras-acides amines basiques, douees de proprietes emollientes, emulsifiantes et antioxydantes, destinees a la cosmetique, la dermatologie et l'alimentation |
IT1233836B (it) * | 1988-01-13 | 1992-04-21 | Euroresearch Srl | Sali idrosolubili dell'acido (+)2-(4 fluorofenil)-alfa-metil-5 benzoxazolo acetato. |
US20020025341A1 (en) * | 1998-12-18 | 2002-02-28 | Yihong Qiu | Controlled release formulation of divalproex sodium |
US20020031549A1 (en) * | 1998-12-18 | 2002-03-14 | Yihong Qiu | Controlled release formulation of divalproex sodium |
US6419953B1 (en) * | 1998-12-18 | 2002-07-16 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
US6528090B2 (en) | 1998-12-18 | 2003-03-04 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
US6511678B2 (en) | 1998-12-18 | 2003-01-28 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
US6713086B2 (en) | 1998-12-18 | 2004-03-30 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
HUP0600526A2 (en) * | 2000-07-21 | 2006-11-28 | Teva Pharma | Use of derivatives of valproic acid and 2-valproenic acid amides for the treatment of mania in bipolar disorder |
ATE301995T1 (de) * | 2000-08-17 | 2005-09-15 | Teva Pharma | Verwendung von derivaten der valproinsäureamide und 2-valproinsäureamid zur behandlung und prävention von schmerzen und/oder kopfschmerzen |
JP3825246B2 (ja) * | 2000-11-24 | 2006-09-27 | Necエレクトロニクス株式会社 | 化学的機械的研磨用スラリー |
WO2002051402A1 (en) * | 2000-12-22 | 2002-07-04 | Abbott Laboratories | Controlled release formulation of divalproex sodium |
US6610326B2 (en) | 2001-02-16 | 2003-08-26 | Andrx Corporation | Divalproex sodium tablets |
WO2004071424A2 (en) * | 2003-02-05 | 2004-08-26 | Teva Pharmaceutical Industries, Ltd. | Immediate release formulation of n-(2-propylpentanoyl)glycinamide |
EP1626707A4 (de) * | 2003-02-05 | 2009-07-01 | Yissum Res Dev Co | Formulierung von n-(2-propylpentanoyl)-glycinamid mit verzögerter freisetzung und verwandten verbindungen |
CA2525366A1 (en) | 2003-05-16 | 2004-11-25 | Pfizer Products Inc. | Therapeutic combinations of atypical antipsychotics with gaba modulators, anticonvulsants or benzodiazapines |
CN1309760C (zh) * | 2003-10-16 | 2007-04-11 | 北京北医投资管理有限公司医药科技开发分公司 | 聚天冬酰甘氨酸、丙氨酸和赖氨酸及其制备方法和医药用途 |
CA2567249A1 (en) * | 2004-04-19 | 2006-10-05 | Jds Pharmaceuticals, Llc | Lithium combinations, and uses related thereto |
US7713550B2 (en) * | 2004-06-15 | 2010-05-11 | Andrx Corporation | Controlled release sodium valproate formulation |
US20050276849A1 (en) * | 2004-06-15 | 2005-12-15 | Nilobon Podhipleux | Sustained release dosage forms |
US20050276848A1 (en) * | 2004-06-15 | 2005-12-15 | Nilobon Podhipleux | Sustained release neutralized divalproex sodium |
AU2006282896A1 (en) | 2005-08-26 | 2007-03-01 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
EP2258358A3 (de) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenese mit Acetylcholinesterasehemmer |
CA2623745A1 (en) * | 2005-09-23 | 2007-04-05 | Janssen Pharmaceutica N.V. | Hexahydro-cycloheptapyrazole cannabinoid modulators |
US8378117B2 (en) * | 2005-09-23 | 2013-02-19 | Janssen Pharmaceutica N.V. | Hexahydro-cycloheptapyrazole cannabinoid modulators |
US7790718B2 (en) * | 2005-09-23 | 2010-09-07 | Janssen Pharmaceutica Nv | Tetrahydro-cyclopentyl pyrazole cannabinoid modulators |
DE602006012514D1 (de) * | 2005-09-23 | 2010-04-08 | Janssen Pharmaceutica Nv | Hexahydro-cyclooctyl-pyrazol-cannabinoid-modulatoren |
US7825151B2 (en) * | 2005-09-23 | 2010-11-02 | Janssen Pharmaceutica Nv | Hexahydro-cyclooctyl pyrazole cannabinoid modulators |
US8378096B2 (en) * | 2005-09-23 | 2013-02-19 | Janssen Pharmaceutica N.V. | Hexahydro-cycloheptapyrazole cannabinoid modulators |
EP1940389A2 (de) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation von neurogenese durch pde-hemmung |
CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20070117858A1 (en) * | 2005-11-23 | 2007-05-24 | Mingde Xia | Substituted 5-heteroaryl-1-phenyl-pyrazole cannabinoid modulators |
EP1979593B1 (de) * | 2006-02-03 | 2017-12-06 | Rolls-Royce Corporation | Gasturbinenantriebsstoffsystem mit treibstoffmessendem ventil |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US8012957B2 (en) * | 2006-03-27 | 2011-09-06 | Janssen Pharmaceutica Nv | Tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulators |
US20070254911A1 (en) * | 2006-03-27 | 2007-11-01 | Mingde Xia | Tetrahydro-Pyrazolo[3,4-c]Pyridine Cannabinoid Modulators |
EP2382975A3 (de) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenese mittels Angiotensin-Modulation |
US7678808B2 (en) | 2006-05-09 | 2010-03-16 | Braincells, Inc. | 5 HT receptor mediated neurogenesis |
JP2010502722A (ja) | 2006-09-08 | 2010-01-28 | ブレインセルス,インコーポレイティド | 4−アシルアミノピリジン誘導体を含む組み合わせ |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US7943653B2 (en) * | 2007-08-13 | 2011-05-17 | Janssen Pharmaceutica N.V. | Substituted 5-vinylphenyl-1-phenyl-pyrazole cannabinoid modulators |
WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
WO2016067297A1 (en) * | 2014-10-27 | 2016-05-06 | Cellix Bio Private Limited | Salts of valproic acid with piperazine, ethylenediamine, lysine and/or eicosapentaenoic ecid (epa) amine derivatives for the treatment of epilepsy |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2662046A (en) * | 1948-06-19 | 1953-12-08 | Merck & Co Inc | Parenteral amino acid solution |
US3024272A (en) * | 1958-04-22 | 1962-03-06 | Du Pont | Organic acid salts of basic amino acids and their use |
FR2442M (fr) * | 1962-10-17 | 1964-04-06 | Henry Eugene | L'acide dipropylacétique et ses dérivés en tant que nouveuax médicaments dépresseurs du systeme nerveux central. |
-
1981
- 1981-11-04 LU LU83729A patent/LU83729A1/fr unknown
-
1982
- 1982-11-03 EP EP82870062A patent/EP0078785B1/de not_active Expired
- 1982-11-03 DE DE8282870062T patent/DE3262899D1/de not_active Expired
- 1982-11-03 AT AT82870062T patent/ATE12485T1/de not_active IP Right Cessation
-
1986
- 1986-05-16 US US06/864,560 patent/US4699927A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
LU83729A1 (fr) | 1983-09-01 |
EP0078785A1 (de) | 1983-05-11 |
US4699927A (en) | 1987-10-13 |
EP0078785B1 (de) | 1985-04-03 |
DE3262899D1 (en) | 1985-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |