ATE116003T1 - Verfahren zur herstellung und reinigung von bernsteinsäure. - Google Patents

Verfahren zur herstellung und reinigung von bernsteinsäure.

Info

Publication number
ATE116003T1
ATE116003T1 AT90301829T AT90301829T ATE116003T1 AT E116003 T1 ATE116003 T1 AT E116003T1 AT 90301829 T AT90301829 T AT 90301829T AT 90301829 T AT90301829 T AT 90301829T AT E116003 T1 ATE116003 T1 AT E116003T1
Authority
AT
Austria
Prior art keywords
succinic acid
producing
acid product
treated
remove
Prior art date
Application number
AT90301829T
Other languages
English (en)
Inventor
David A Glassner
Rathin Datta
Original Assignee
Michigan Biotech Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Michigan Biotech Inst filed Critical Michigan Biotech Inst
Application granted granted Critical
Publication of ATE116003T1 publication Critical patent/ATE116003T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AT90301829T 1989-03-17 1990-02-20 Verfahren zur herstellung und reinigung von bernsteinsäure. ATE116003T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/325,404 US5143834A (en) 1986-06-11 1989-03-17 Process for the production and purification of succinic acid

Publications (1)

Publication Number Publication Date
ATE116003T1 true ATE116003T1 (de) 1995-01-15

Family

ID=23267752

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90301829T ATE116003T1 (de) 1989-03-17 1990-02-20 Verfahren zur herstellung und reinigung von bernsteinsäure.

Country Status (7)

Country Link
US (1) US5143834A (de)
EP (1) EP0389103B1 (de)
JP (1) JP2872723B2 (de)
AT (1) ATE116003T1 (de)
CA (1) CA1334583C (de)
DE (1) DE69015233T2 (de)
NZ (1) NZ231315A (de)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2691457A1 (fr) * 1992-05-20 1993-11-26 Rhone Poulenc Chimie Procédé d'hydrolyse de dicarboxylate d'alkyle.
FR2698245B1 (fr) * 1992-11-25 1996-08-23 Int Flavors & Fragrances Inc Utilisation des acides aconitique, gluconique et/ou succinique seuls ou ensemble avec la sclareolide pour augmenter les proprietes organoleptiques des produits alimentaires.
AT398982B (de) * 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms
US5573931A (en) * 1995-08-28 1996-11-12 Michigan Biotechnology Institute Method for making succinic acid, bacterial variants for use in the process, and methods for obtaining variants
US5869301A (en) * 1995-11-02 1999-02-09 Lockhead Martin Energy Research Corporation Method for the production of dicarboxylic acids
US5770435A (en) * 1995-11-02 1998-06-23 University Of Chicago Mutant E. coli strain with increased succinic acid production
US5645703A (en) * 1995-12-20 1997-07-08 University Of Chicago Electrodialysis-based separation process for salt recovery and recycling from waste water
US5766439A (en) * 1996-10-10 1998-06-16 A. E. Staley Manufacturing Co. Production and recovery of organic acids
US5958744A (en) * 1997-08-18 1999-09-28 Applied Carbochemicals Succinic acid production and purification
US20030087381A1 (en) * 1998-04-13 2003-05-08 University Of Georgia Research Foundation, Inc. Metabolically engineered organisms for enhanced production of oxaloacetate-derived biochemicals
AR015762A1 (es) 1998-04-13 2001-05-16 Univ Georgia Una celula manipulada por ingenieria metabolica; un metodo para producir dicha celula; un metodo para producir una sustancia bioquimica derivada deoxalacetato y un fragmento de acido nucleico aislado de p. fluorescens
US6187570B1 (en) 1998-05-26 2001-02-13 The Electrosynthesis Company, Inc. Electrodialysis methods for purification and recovery of gluconic acid derivatives
US6509179B1 (en) 2000-10-12 2003-01-21 Barbara I. Veldhuis-Stribos Continuous process for preparing lactic acid
FR2816308B1 (fr) * 2000-11-09 2005-04-08 Saf Isis Procede de production en continu d'un sel concentre d'acide succinique
US6933381B2 (en) 2001-02-02 2005-08-23 Charles B. Mallon Method of preparing modified cellulose ether
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
CN100575496C (zh) * 2003-08-28 2009-12-30 三菱化学株式会社 产生琥珀酸的方法
EP1672067B1 (de) * 2003-09-17 2015-11-11 Mitsubishi Chemical Corporation Verfahren zur herstellung einer organischen nicht-amino-säure
WO2005030973A1 (ja) 2003-09-30 2005-04-07 Ajinomoto Co., Inc. 発酵液からのコハク酸の精製方法
JP4301918B2 (ja) * 2003-11-06 2009-07-22 三菱化学株式会社 ポリエステルの製造方法
BRPI0416274A (pt) * 2003-11-07 2007-01-09 Mitsubishi Chemical Corp E Aji método para produzir solução de amÈnio de ácido orgánico
US6846431B1 (en) 2003-12-26 2005-01-25 Diversified Natural Products, Inc. Environmentally benign, non-toxic, non-corrosive engine coolant/antifreeze
BRPI0510919A (pt) 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
WO2005113745A1 (ja) * 2004-05-20 2005-12-01 Ajinomoto Co., Inc. コハク酸生産菌及びコハク酸の製造方法
JP4554277B2 (ja) * 2004-05-27 2010-09-29 昭和電工株式会社 微生物によるコハク酸の製造方法
EP1659197A1 (de) * 2004-11-18 2006-05-24 Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO Verfahren zur zurückgewinnung von Säuren
EP3909998A3 (de) 2005-04-22 2022-03-16 Mitsubishi Chemical Corporation Aus einer biomassenressource gewonnenes polyester und herstellungsverfahren dafür
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
KR100676160B1 (ko) * 2005-08-19 2007-02-01 한국과학기술원 말릭효소를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100727054B1 (ko) * 2005-08-19 2007-06-12 한국과학기술원 푸마레이트 하이드라타제 c를 코딩하는 유전자로 형질전환된 재조합 미생물 및 이를 이용한 숙신산의 제조방법
KR100679638B1 (ko) * 2005-08-19 2007-02-06 한국과학기술원 포메이트 디하이드로게나제 d 또는 e를 코딩하는 유전자로 형질전환된 미생물 및 이를 이용한 숙신산의 제조방법
CN101300356A (zh) * 2005-09-09 2008-11-05 基因组股份公司 用于琥珀酸盐之生长关联性生产的方法和生物
EP1947190B1 (de) * 2005-10-18 2017-11-29 Ajinomoto Co., Inc. Verfahren zur herstellung von bernsteinsäure
WO2007099867A1 (ja) 2006-02-24 2007-09-07 Mitsubishi Chemical Corporation 有機酸生産菌及び有機酸の製造法
KR100762962B1 (ko) * 2006-05-04 2007-10-04 한국과학기술원 게놈정보 및 인실리코 분석을 이용한 배양배지의 제조방법
WO2008010373A1 (en) * 2006-07-19 2008-01-24 Showa Denko K.K. A process for producing succinic acid
KR100780324B1 (ko) 2006-07-28 2007-11-29 한국과학기술원 신규 순수 숙신산 생성 변이 미생물 및 이를 이용한 숙신산제조방법
WO2008091627A2 (en) * 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
EP2570481B1 (de) 2007-03-20 2014-11-26 University of Florida Research Foundation, Inc. Materialien und Verfahren zur effizienten Succinat- und Malatherstellung
DE102007019184A1 (de) 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
WO2008143015A1 (ja) 2007-05-18 2008-11-27 Ajinomoto Co., Inc. コハク酸およびコハク酸アンモニウム溶液の製造方法
CA2696018A1 (en) * 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of olefins and derivatives
CN101153294B (zh) * 2007-08-30 2010-11-10 合肥工业大学 琥珀酸的固定化细胞单罐高强度连续发酵工艺
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
ITMI20080080A1 (it) * 2008-01-18 2009-07-19 Eni Spa Processo per il trattamento della corrente acquosa proveniente dalla reazione fischer-tropsch
US7803589B2 (en) * 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
CA3081506A1 (en) * 2008-03-05 2009-09-11 Genomatica, Inc. Long chain alcohol-producing organisms
HUE035611T2 (en) * 2008-03-27 2018-05-28 Genomatica Inc Microorganisms suitable for the production of adipic acid and other compounds
AU2009242615A1 (en) 2008-05-01 2009-11-05 Genomatica, Inc. Microorganisms for the production of methacrylic acid
US8129154B2 (en) * 2008-06-17 2012-03-06 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
CN101348428B (zh) * 2008-09-05 2011-01-05 江南大学 一种阴离子树脂吸附提取发酵液中丁二酸的方法
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
BRPI0922276A2 (pt) * 2008-12-16 2015-08-04 Genomatica Inc "organismo microbiano de ocorrência não-natural, e , método para produzir isopropanol, 4-hidroxibutirato,e, 1,4-butanodiol."
EP2425006A4 (de) 2009-04-30 2013-01-23 Genomatica Inc Organismen zur herstellung von isopropanol, n-butanol und isobutanol
JP5876822B2 (ja) 2009-04-30 2016-03-02 ゲノマチカ, インク. 1,3−ブタンジオールの産生のための生物
EP2427544B1 (de) 2009-05-07 2019-07-17 Genomatica, Inc. Mikrooganismen und verfahren für die biosynthese von adipat, hexamethylendiamin und 6-aminocapronsäure
EP2429587A4 (de) * 2009-05-15 2014-10-08 Genomatica Inc Organismen zur herstellung von cyclohexanon
US8420375B2 (en) 2009-06-10 2013-04-16 Genomatica, Inc. Microorganisms and methods for carbon-efficient biosynthesis of MEK and 2-butanol
US20120168310A1 (en) * 2009-07-01 2012-07-05 Novozymes, Inc. Process for separating and recovering C4 dicarboxylic acids
WO2011017560A1 (en) 2009-08-05 2011-02-10 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
EP2475775A4 (de) 2009-09-09 2013-03-20 Genomatica Inc Mikroorganismen und verfahren zur gleichzeitigen herstellung von isopropanol und primären alkoholen, diolen und säuren
CA2777459A1 (en) 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
KR20120088753A (ko) * 2009-10-23 2012-08-08 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
US20120238722A1 (en) 2009-11-24 2012-09-20 Roquette Freres Sa Process for the crystallization of succinic acid
EP2733137A1 (de) 2009-12-02 2014-05-21 Board Of Trustees Of Michigan State University Rückgewinnung von Carbonsäure und zugehörige Verfahren
JP2013513384A (ja) * 2009-12-10 2013-04-22 ジェノマティカ・インコーポレイテッド 合成ガスまたは他のガス状の炭素源およびメタノールを1,3−ブタンジオールへ変換するための方法および生物
CN102781900A (zh) 2009-12-31 2012-11-14 麦兰特公司 从含有琥珀酸铵的发酵液纯化琥珀酸
KR20120123742A (ko) 2010-01-29 2012-11-09 게노마티카 인코포레이티드 P-톨루에이트 및 테레프탈레이트 생합성 미생물 및 생합성 방법
EP2360137B1 (de) 2010-02-12 2013-08-07 PURAC Biochem BV Verfahren zur Herstellung von Bernsteinsäure
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
WO2011140171A2 (en) 2010-05-05 2011-11-10 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
DE102010025167A1 (de) 2010-06-25 2011-12-29 Uhde Gmbh Verfahren zur Abtrennung, Gewinnung und Reinigung von Bernsteinsäure
WO2012018624A2 (en) 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
EP2687591B1 (de) 2011-03-18 2021-01-06 Mitsubishi Chemical Corporation Verfahren zur herstellung von polymeren, herstellungsverfahren für organische säuren und organische säuren produzierender mikroorganismus
US8580096B2 (en) 2011-09-29 2013-11-12 Uchicago Argonne, Llc Bioprocess utilizing carbon dioxide and electrodeionization
DE102011120632A1 (de) 2011-12-09 2013-06-13 Thyssenkrupp Uhde Gmbh Verfahren zur Aufreinigung von Carbonsäuren aus Fermentationsbrühen
FR2987678B1 (fr) 2012-03-02 2016-04-15 Roquette Freres Methode de mesure de la stabilite thermique d'un acide succinique cristallin destine a la fabrication de polymeres
ITPD20120332A1 (it) * 2012-11-07 2014-05-08 Enologica Vason S P A Procedimento ed impianto per l'estrazione di composti acidi indesiderati da un liquido alimentare ed in particolare da un vino
EP2745905A1 (de) 2012-12-21 2014-06-25 ThyssenKrupp Uhde GmbH Verfahren zur Reinigung von Carboxylsäuren durch subkritische oder superkritische Chromatography
DE102013000027A1 (de) 2013-01-03 2014-07-03 Thyssenkrupp Industrial Solutions Ag Verfahren zur Aufreinigung von Carbonsäuren aus Fermentationsbrühen
WO2014108163A2 (de) 2013-01-11 2014-07-17 Thyssenkrupp Uhde Gmbh Verfahren zur herstellung von dicarbonsäuren
NZ706072A (en) * 2013-03-08 2018-12-21 Xyleco Inc Equipment protecting enclosures
WO2014142572A1 (ko) * 2013-03-14 2014-09-18 주식회사 제이 엔 에스 텍 전통 장류식품 미생물을 이용한 소금의 나트륨 제거방법 및 이에 의해 생산된 소금
CN104178443B (zh) 2013-05-24 2017-04-12 中国科学院天津工业生物技术研究所 生产丁二酸的重组大肠杆菌及其应用
JP2015080744A (ja) * 2013-10-22 2015-04-27 三菱化学株式会社 脂肪族ジカルボン酸含有液の製造方法
TW201538477A (zh) 2013-12-06 2015-10-16 Myriant Corp 製備丁二酸酯之方法
JP2014133899A (ja) * 2014-04-23 2014-07-24 Mitsubishi Chemicals Corp バイオマス資源由来ポリエステル製延伸フィルム
PL236607B1 (pl) * 2017-11-09 2021-02-08 Politechnika Poznanska Sposób wydzielania kwasu bursztynowego z brzeczki fermentacyjnej

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110175A (en) * 1976-06-30 1978-08-29 Aqua-Chem, Inc. Electrodialysis method
FR2555200B1 (fr) * 1983-11-23 1986-07-25 Centre Nat Rech Scient Procede de preparation d'acide lactique par fermentation de lactoserum et installation pour la mise en oeuvre en continu de ce procede
DE3434918A1 (de) * 1984-09-22 1986-04-03 Hüls AG, 4370 Marl Verfahren zur gewinnung von l-aepfelsaeure
US4766161A (en) * 1986-06-05 1988-08-23 Allied Corporation Bipolar membranes and methods of making same
DE3783081T2 (de) * 1986-06-11 1993-04-15 Michigan Biotech Inst Verfahren zur herstellung von bernsteinsaeure durch anaerobe fermentation.
US4678553A (en) * 1986-07-11 1987-07-07 Ionics, Incorporated Renaturing reversibly denatured polypeptides and proteins by electrodialysis of solutions thereof in denaturants

Also Published As

Publication number Publication date
NZ231315A (en) 1992-02-25
CA1334583C (en) 1995-02-28
DE69015233T2 (de) 1995-08-24
AU4938590A (en) 1990-09-20
EP0389103A1 (de) 1990-09-26
EP0389103B1 (de) 1994-12-21
JP2872723B2 (ja) 1999-03-24
DE69015233D1 (de) 1995-02-02
US5143834A (en) 1992-09-01
AU626381B2 (en) 1992-07-30
JPH02283289A (ja) 1990-11-20

Similar Documents

Publication Publication Date Title
ATE116003T1 (de) Verfahren zur herstellung und reinigung von bernsteinsäure.
ATE115629T1 (de) Verfahren zur fermentation und isolierung von bernsteinsäure.
DE3570866D1 (en) Process for the isolation of citric acid
DE68913595D1 (de) Herstellung von organischen Säuren durch Fermentation.
ATE236114T1 (de) Verfahren zur trennung und reinigung von milchsäure aus einem fermentationsmedium
ATE162113T1 (de) Verfahren zur konditionierung von ionenaustauschharzen
ATE88615T1 (de) Milchsaeurehaltige fruchtprodukte und verfahren zur lactofermentation von fruchtprodukten.
DE59107901D1 (de) Verfahren zur herstellung gereinigter glycolipide durch membrantrennverfahren
ATE110979T1 (de) Verfahren zur rückgewinnung von säuren aus sauren und salzhaltigen lösungen.
DE69213876D1 (de) Verfahren zum Abtrennen von Lysine in Form von einer wässerigen Lösung und Verwendung dieser Lösung in der Tierernährung
ATE55706T1 (de) Verfahren zur gewinnung von organischen saeuren.
DE3684434D1 (de) Verfahren zur herstellung von 2-keto-d-glukarsaeure.
ATE117024T1 (de) Verfahren zur abtrennung von keto-2l-gulonsäure aus fermentationsbrühe.
ATE63313T1 (de) Verfahren zur herstellung von niedermolekularen alkalihuminaten.
DE69305826D1 (de) Verfahren zur Herstellung von Alkalimetallcitrat
KR910019961A (ko) 글리신의 정제방법
DE50008648D1 (de) Verfahren zum Feinreinigen einer wässrigen Lösung, die eine fermentativ hergestellte organische Säure enthält
ATE32916T1 (de) Verfahren zur gewinnung von l-aepfelsaeure.
DE59209053D1 (de) Verfahren zur Herstellung aktivierter Sialinsäuren
ATE124954T1 (de) Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat.
ATE135369T1 (de) Chemisches verfahren zur herstellung des antibiotikums l 17392 (deglukoteicoplanin) und dessen salze
DE69005993D1 (de) Verfahren zur Herstellung eines Ranitidin-Harz-Absorbates.
ATE144554T1 (de) Mikrobiologisches verfahren zur herstellung von 6-hydroxypyrazincarbonsäure
JPS5682098A (en) Production of purine nucleoside-5'-monophosphate
JPS5799198A (en) Preparation of l-phenylalanine

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties