ATE109485T1 - Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number: ATE109485T1
Authority: AT; Austria
Prior art keywords: radical; carbon atoms; denotes; linear; hydrogen atom
Prior art date: 1989-08-04

Application number

AT90402226T

Other languages

English (en)

Inventor

Gilbert Lavielle

Patrick Hautefaye

Alain Pierre

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-04

Filing date

1990-08-03

Publication date

1994-08-15

1990-08-03 Application filed by Adir filed Critical Adir

1994-08-15 Application granted granted Critical

1994-08-15 Publication of ATE109485T1 publication Critical patent/ATE109485T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

AT90402226T 1989-08-04 1990-08-03 Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE109485T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8910554A FR2651348B1 (de)	1989-08-04	1989-08-04

Publications (1)

Publication Number	Publication Date
ATE109485T1 true ATE109485T1 (de)	1994-08-15

Family

ID=9384495

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90402226T ATE109485T1 (de)	1989-08-04	1990-08-03	Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (15)

Country	Link
US (1)	US5100881A (de)
EP (1)	EP0412015B1 (de)
JP (1)	JPH075619B2 (de)
AT (1)	ATE109485T1 (de)
AU (1)	AU625885B2 (de)
CA (1)	CA2022538C (de)
DE (1)	DE69011235T2 (de)
DK (1)	DK0412015T3 (de)
ES (1)	ES2060979T3 (de)
FR (1)	FR2651348B1 (de)
IE (1)	IE66007B1 (de)
NZ (1)	NZ234771A (de)
OA (1)	OA09299A (de)
PT (1)	PT94906B (de)
ZA (1)	ZA905924B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5508463A (en) *	1994-03-17	1996-04-16	Trustees Of The University Of Pennsylvania	α-aminophosphonates
EP2266607A3 (de)	1999-10-01	2011-04-20	Immunogen, Inc.	Immunokonjugate für Krebsbehandlung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3354163A (en) *	1966-12-15	1967-11-21	Eli Lillty And Company	Nu-desmethylvinblastine
HU165986B (de) *	1973-02-16	1974-12-28
US4307100A (en) *	1978-08-24	1981-12-22	Agence Nationale De Valorisation De La Recherche (Anvar)	Nor bis-indole compounds usable as medicaments
US4210584A (en) *	1979-01-15	1980-07-01	Eli Lilly And Company	Vindesine synthesis
LU84640A1 (fr) *	1983-02-10	1984-11-08	Onmichem S A	Nouveau procede d'obtention de la vincristine et du sulfate de vincristine
US4619935A (en) *	1983-03-17	1986-10-28	Eli Lilly And Company	Stable oncolytic formulations
US4522750A (en) *	1984-02-21	1985-06-11	Eli Lilly And Company	Cytotoxic compositions of transferrin coupled to vinca alkaloids
FR2623504B1 (fr) *	1987-11-25	1990-03-09	Adir	Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US4923876A (en) *	1988-04-18	1990-05-08	Cetus Corporation	Vinca alkaloid pharmaceutical compositions

1989
- 1989-08-04 FR FR8910554A patent/FR2651348B1/fr not_active Expired - Fee Related
1990
- 1990-07-27 ZA ZA905924A patent/ZA905924B/xx unknown
- 1990-08-01 US US07/561,065 patent/US5100881A/en not_active Expired - Fee Related
- 1990-08-02 CA CA002022538A patent/CA2022538C/fr not_active Expired - Fee Related
- 1990-08-03 EP EP90402226A patent/EP0412015B1/de not_active Expired - Lifetime
- 1990-08-03 NZ NZ234771A patent/NZ234771A/en unknown
- 1990-08-03 OA OA59827A patent/OA09299A/xx unknown
- 1990-08-03 PT PT94906A patent/PT94906B/pt not_active IP Right Cessation
- 1990-08-03 DK DK90402226.6T patent/DK0412015T3/da active
- 1990-08-03 IE IE280890A patent/IE66007B1/en not_active IP Right Cessation
- 1990-08-03 DE DE69011235T patent/DE69011235T2/de not_active Expired - Fee Related
- 1990-08-03 AU AU60149/90A patent/AU625885B2/en not_active Ceased
- 1990-08-03 AT AT90402226T patent/ATE109485T1/de active
- 1990-08-03 ES ES90402226T patent/ES2060979T3/es not_active Expired - Lifetime
- 1990-08-03 JP JP2206668A patent/JPH075619B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PT94906B (pt)	1997-03-31
JPH03118388A (ja)	1991-05-20
IE66007B1 (en)	1995-11-29
FR2651348A1 (de)	1991-03-01
ZA905924B (en)	1991-05-29
DE69011235D1 (de)	1994-09-08
EP0412015B1 (de)	1994-08-03
CA2022538A1 (fr)	1991-02-05
DK0412015T3 (da)	1994-11-28
EP0412015A1 (de)	1991-02-06
PT94906A (pt)	1991-04-18
CA2022538C (fr)	1996-09-24
DE69011235T2 (de)	1995-03-09
OA09299A (fr)	1992-09-15
IE902808A1 (en)	1991-02-27
AU6014990A (en)	1991-02-07
ES2060979T3 (es)	1994-12-01
JPH075619B2 (ja)	1995-01-25
FR2651348B1 (de)	1993-01-22
NZ234771A (en)	1992-05-26
US5100881A (en)	1992-03-31
AU625885B2 (en)	1992-07-16

Publication	Publication Date	Title
DE69103206D1 (de)	1994-09-08	Neue Derivate des Aminopiperidins, Aminopyrrolidins und des Aminoperhydroazepins, Verfahren zur Herstellung und diese enthaltende Arzneimittel.
NZ234110A (en)	1993-01-27	Dibenzoazepine, -oxepine and -cycloheptane substituted alkylidene amines; pharmaceutical compositions containing such compounds or various other aryl substituted amines
OA08972A (fr)	1990-11-30	Nouveaux dérivés N-(vinblastinoyl-23) d'acide amino-1 méthylphosphonique, leursprocédés de préparation et les compositions pharmaceutiques qui les contiennent
ATE109485T1 (de)	1994-08-15	Derivate von n-(vincristinyl-23) und n- (noranhydro-5-vinblastinyl-23) von amino-1- methylphosphonsäure, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE69611T1 (de)	1991-12-15	Piperazinylalkylpiperazindion-derivate, ihre verfahren zur herstellung und diese enthaltende pharmazeutische zusammenstellungen.
ATE16383T1 (de)	1985-11-15	Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
ATE56442T1 (de)	1990-09-15	2,6-piperazin-dion-derivate, ihre verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzungen.
MX9206149A (es)	1993-08-01	N-(mercaptoacil)amino acidos, metodos para su preparcion y uso terapeutico, y composiciones farmaceuticas que los contienen
DE3783821T2 (de)	1993-05-27	Tetracyclische indolderivate.