ATE106893T1 - Verfahren zur herstellung von aktiviertem protein c. - Google Patents

Verfahren zur herstellung von aktiviertem protein c.

Info

Publication number
ATE106893T1
ATE106893T1 AT90907093T AT90907093T ATE106893T1 AT E106893 T1 ATE106893 T1 AT E106893T1 AT 90907093 T AT90907093 T AT 90907093T AT 90907093 T AT90907093 T AT 90907093T AT E106893 T1 ATE106893 T1 AT E106893T1
Authority
AT
Austria
Prior art keywords
activated protein
pct
sec
production
aprotinin
Prior art date
Application number
AT90907093T
Other languages
English (en)
Inventor
Marion Steinbuch
Jacques Chabbat
Olivier Taby
Original Assignee
Fond Nat Transfusion Sanguine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8904814A external-priority patent/FR2645865B1/fr
Application filed by Fond Nat Transfusion Sanguine filed Critical Fond Nat Transfusion Sanguine
Application granted granted Critical
Publication of ATE106893T1 publication Critical patent/ATE106893T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT90907093T 1989-04-12 1990-04-10 Verfahren zur herstellung von aktiviertem protein c. ATE106893T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8904814A FR2645865B1 (fr) 1989-04-12 1989-04-12 Procede de preparation de la proteine c activee et solution de proteine c activee ainsi obtenue
FR909002028A FR2658517B2 (fr) 1989-04-12 1990-02-20 Preparation de la proteine c activee et solution de proteine c activee ainsi obtenue.

Publications (1)

Publication Number Publication Date
ATE106893T1 true ATE106893T1 (de) 1994-06-15

Family

ID=26227270

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90907093T ATE106893T1 (de) 1989-04-12 1990-04-10 Verfahren zur herstellung von aktiviertem protein c.

Country Status (13)

Country Link
US (1) US5198534A (de)
EP (1) EP0424498B1 (de)
JP (1) JPH03505531A (de)
KR (1) KR920700220A (de)
AT (1) ATE106893T1 (de)
CA (1) CA2030783A1 (de)
DE (1) DE69009668T2 (de)
DK (1) DK0424498T3 (de)
ES (1) ES2054355T3 (de)
FR (1) FR2658517B2 (de)
MA (1) MA21807A1 (de)
PL (1) PL284757A1 (de)
WO (1) WO1990012028A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT397615B (de) * 1991-05-14 1994-05-25 Immuno Ag Arzneimittel enthaltend protein c
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c
DE4320294A1 (de) * 1993-06-18 1994-12-22 Immuno Ag Verwendung von humanem Protein C zur Verhinderung und Behandlung von Thrombozytenablagerungen
US6867045B1 (en) * 1994-11-14 2005-03-15 The Scripps Research Institute Method for diagnosis of thrombotic disorders
JP3745805B2 (ja) * 1995-10-24 2006-02-15 日本ケミカルリサーチ株式会社 トロンボモジュリンの精製方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8319538D0 (en) * 1983-07-20 1983-08-24 Beecham Group Plc Compounds
US4849403A (en) * 1985-05-29 1989-07-18 Pentapharm Ag Protein C activator, methods of preparation and use thereof
DE3882411T2 (de) * 1987-04-17 1993-12-16 Teijin Ltd Verfahren zur Trennung von aktiviertem menschlichem Protein C.

Also Published As

Publication number Publication date
FR2658517A2 (fr) 1991-08-23
EP0424498B1 (de) 1994-06-08
FR2658517B2 (fr) 1992-06-19
MA21807A1 (fr) 1990-12-31
EP0424498A1 (de) 1991-05-02
US5198534A (en) 1993-03-30
KR920700220A (ko) 1992-02-19
JPH03505531A (ja) 1991-12-05
DE69009668D1 (de) 1994-07-14
WO1990012028A1 (fr) 1990-10-18
PL284757A1 (en) 1991-01-14
DK0424498T3 (da) 1994-07-04
ES2054355T3 (es) 1994-08-01
DE69009668T2 (de) 1994-10-06
CA2030783A1 (fr) 1990-10-13

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee