ATE102618T1 - Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide. - Google Patents

Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide.

Info

Publication number
ATE102618T1
ATE102618T1 AT91104943T AT91104943T ATE102618T1 AT E102618 T1 ATE102618 T1 AT E102618T1 AT 91104943 T AT91104943 T AT 91104943T AT 91104943 T AT91104943 T AT 91104943T AT E102618 T1 ATE102618 T1 AT E102618T1
Authority
AT
Austria
Prior art keywords
substituted
indolesulfonamides
dihydroindols
cycloalcano
heterocyclic ring
Prior art date
Application number
AT91104943T
Other languages
English (en)
Inventor
Ulrich E Dr Mueller
Ulrich Dr Rosentreter
Ulrich Dr Niewoehner
Elisabeth Dr Perzborn
Erwin Dr Bischoff
Hans-Georg Dr Dellweg
Peter Dr Norman
Nigel J Dr Cuthbert
Hilary P Dr Francis
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE102618T1 publication Critical patent/ATE102618T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT91104943T 1990-04-10 1991-03-28 Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide. ATE102618T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909008108A GB9008108D0 (en) 1990-04-10 1990-04-10 Cycloalkano(b)dihydroindoles and-indolesulphonamides substituted by heterocycles

Publications (1)

Publication Number Publication Date
ATE102618T1 true ATE102618T1 (de) 1994-03-15

Family

ID=10674203

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91104943T ATE102618T1 (de) 1990-04-10 1991-03-28 Mit einem heterocyclischen ring substituierte cycloalkano(b>dihydroindole und indolsulfonamide.

Country Status (18)

Country Link
US (1) US5204374A (de)
EP (1) EP0451634B1 (de)
JP (1) JPH04234846A (de)
KR (1) KR910018374A (de)
AT (1) ATE102618T1 (de)
AU (1) AU632213B2 (de)
CA (1) CA2039873A1 (de)
DE (1) DE69101330T2 (de)
DK (1) DK0451634T3 (de)
ES (1) ES2062591T3 (de)
GB (1) GB9008108D0 (de)
HU (1) HU209645B (de)
IE (1) IE64843B1 (de)
IL (1) IL97795A (de)
NZ (1) NZ237709A (de)
PT (1) PT97280A (de)
TW (1) TW221995B (de)
ZA (1) ZA912609B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464746A (en) * 1991-12-17 1995-11-07 Abbott Laboratories Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives
AU4685693A (en) * 1993-07-20 1995-02-20 Abbott Laboratories Haptens, tracers, immunogens and antibodies for carbazole and dibenzofuran derivatives
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
WO2003097598A1 (fr) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Composé comprenant un antagonisme du récepteur de pdg2
WO2003097042A1 (fr) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Antagoniste de recepteur de pdg2
JP2007501284A (ja) * 2003-06-10 2007-01-25 スミスクライン ビーチャム コーポレーション テトラヒドロカルバゾール誘導体およびそれらの薬学的使用
AU2004256052A1 (en) 2003-06-12 2005-01-20 Smithkline Beecham Corporation Tetrahydrocarbazole derivatives and their pharmaceutical use
DK1902026T3 (da) * 2005-06-24 2010-04-26 Lilly Co Eli Tetrahydrocarbazol-derivater, der kan anvendes som androgen-receptor-modulatorer (SARM)
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
UA98777C2 (en) * 2006-11-20 2012-06-25 Эли Лилли Энд Компани Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators
CN101434571B (zh) * 2007-11-13 2012-05-30 杭州容立医药科技有限公司 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法
PT2297100E (pt) * 2008-05-16 2013-01-24 Lilly Co Eli Moduladores dos receptores de andrógenos tetra-hidrociclopenta[b]indoles
US8501959B2 (en) * 2008-06-24 2013-08-06 Panmira Pharmaceuticals, Llc Cycloalkane[B]indole antagonists of prostaglandin D2 receptors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3946021A (en) * 1970-07-23 1976-03-23 Richardson-Merrell Inc. Bis-basic ketones of carbazole
US3975398A (en) * 1973-08-01 1976-08-17 Boehringer Mannheim G.M.B.H. 9-Substituted 3-aminocarbazole compounds
US4464379A (en) * 1981-06-01 1984-08-07 A. Nattermann & Cie Gmbh Indol acetic acid derivatives and anti-inflamatory and related uses thereof
DE3514696A1 (de) * 1985-04-24 1986-11-06 Bayer Ag, 5090 Leverkusen N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US4940719A (en) * 1986-03-27 1990-07-10 Merck Frosst Canada, Inc. Tetrahydrocarbazole esters, pharmaceutical compositions and use
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide

Also Published As

Publication number Publication date
ES2062591T3 (es) 1994-12-16
KR910018374A (ko) 1991-11-30
IL97795A (en) 1995-08-31
HUT57205A (en) 1991-11-28
EP0451634B1 (de) 1994-03-09
US5204374A (en) 1993-04-20
GB9008108D0 (en) 1990-06-06
AU632213B2 (en) 1992-12-17
TW221995B (de) 1994-04-01
EP0451634A3 (en) 1992-01-02
ZA912609B (en) 1992-01-29
EP0451634A2 (de) 1991-10-16
PT97280A (pt) 1992-01-31
DK0451634T3 (da) 1994-05-02
DE69101330T2 (de) 1994-06-16
AU7425291A (en) 1991-10-17
DE69101330D1 (de) 1994-04-14
IE911186A1 (en) 1991-10-23
HU911140D0 (en) 1991-10-28
CA2039873A1 (en) 1991-10-11
NZ237709A (en) 1992-10-28
IE64843B1 (en) 1995-09-06
IL97795A0 (en) 1992-06-21
JPH04234846A (ja) 1992-08-24
HU209645B (en) 1994-09-28

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee