ATA53984A - Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen - Google Patents
Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzenInfo
- Publication number
- ATA53984A ATA53984A AT84539A AT53984A ATA53984A AT A53984 A ATA53984 A AT A53984A AT 84539 A AT84539 A AT 84539A AT 53984 A AT53984 A AT 53984A AT A53984 A ATA53984 A AT A53984A
- Authority
- AT
- Austria
- Prior art keywords
- diones
- salts
- producing new
- substituted oxazolidin
- oxazolidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
- C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0053984A AT376976B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17320680A | 1980-07-28 | 1980-07-28 | |
US06/252,962 US4342771A (en) | 1981-01-02 | 1981-04-23 | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
US06/252,961 US4332952A (en) | 1980-07-28 | 1981-04-23 | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
AT0328881A AT376974B (de) | 1980-07-28 | 1981-07-24 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
AT0053984A AT376976B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA53984A true ATA53984A (de) | 1984-06-15 |
AT376976B AT376976B (de) | 1985-01-25 |
Family
ID=26868873
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0053984A AT376976B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
AT0053884A AT376975B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
AT0054084A AT376977B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0053884A AT376975B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
AT0054084A AT376977B (de) | 1980-07-28 | 1984-02-17 | Verfahren zur herstellung von neuen 5-substituierten oxazolidin-2,4-dionen und ihren salzen |
Country Status (3)
Country | Link |
---|---|
US (1) | US4332952A (de) |
AT (3) | AT376976B (de) |
CS (2) | CS237346B2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4689336A (en) * | 1981-01-02 | 1987-08-25 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine 2,4-diones |
US4423233A (en) * | 1981-04-23 | 1983-12-27 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
US4430337A (en) | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
CA1334975C (en) * | 1987-11-13 | 1995-03-28 | James H. Holms | Furan and pyrrole containing lipoxygenase inhibiting compounds |
WO1991007107A1 (en) * | 1989-11-13 | 1991-05-30 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
US5498621A (en) * | 1992-05-01 | 1996-03-12 | Pfizer Inc. | Oxazolidinedione hypoglycemic agents |
US5401761A (en) * | 1993-12-09 | 1995-03-28 | Pfizer, Inc. | Thiazolidinedione hypoglycemic agents |
TW403748B (en) * | 1994-11-02 | 2000-09-01 | Takeda Chemical Industries Ltd | An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same |
EP1194146B1 (de) | 1999-06-18 | 2006-07-19 | Merck & Co., Inc. | Arylthiazolidinedione und aryloxa zolidinedion-derivate |
CA2377246A1 (en) | 1999-06-18 | 2000-12-28 | Ranjit C. Desai | Arylthiazolidinedione and aryloxazolidinedione derivatives |
US6638929B2 (en) | 1999-12-29 | 2003-10-28 | Wyeth | Tricyclic protein kinase inhibitors |
US6521618B2 (en) | 2000-03-28 | 2003-02-18 | Wyeth | 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors |
US7491743B2 (en) * | 2003-08-29 | 2009-02-17 | President And Fellows Of Harvard College | Inhibitors of cellular necrosis |
CN102316735A (zh) | 2008-12-23 | 2012-01-11 | 哈佛大学校长及研究员协会 | 坏死性凋亡的小分子抑制剂 |
JP2016514693A (ja) | 2013-03-15 | 2016-05-23 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ハイブリッド型ネクロトーシス阻害剤 |
JP2017538712A (ja) | 2014-12-11 | 2017-12-28 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 細胞壊死の抑制剤及びそれに関連する方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2338220A (en) * | 1942-01-31 | 1944-01-04 | Mallinckrodt Chemical Works | Process of making oxazolidinediones |
US2721197A (en) * | 1953-01-05 | 1955-10-18 | Bristol Lab Inc | Bicyclic lactams |
US3699229A (en) * | 1970-12-18 | 1972-10-17 | Abbott Lab | 2-oxo-5-phenyl-4-oxazolidinone as an anti-depressant agent |
DE2813873A1 (de) * | 1978-03-31 | 1979-10-11 | Basf Ag | Verfahren zur herstellung von oxazolidin-2,4-dionen |
-
1981
- 1981-04-23 US US06/252,961 patent/US4332952A/en not_active Expired - Lifetime
- 1981-07-23 CS CS838032A patent/CS237346B2/cs unknown
-
1983
- 1983-10-31 CS CS838034A patent/CS237348B2/cs unknown
-
1984
- 1984-02-17 AT AT0053984A patent/AT376976B/de not_active IP Right Cessation
- 1984-02-17 AT AT0053884A patent/AT376975B/de not_active IP Right Cessation
- 1984-02-17 AT AT0054084A patent/AT376977B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CS237346B2 (en) | 1985-07-16 |
CS237348B2 (en) | 1985-07-16 |
ATA53884A (de) | 1984-06-15 |
ATA54084A (de) | 1984-06-15 |
CS803283A2 (en) | 1984-12-14 |
US4332952A (en) | 1982-06-01 |
AT376977B (de) | 1985-01-25 |
AT376976B (de) | 1985-01-25 |
AT376975B (de) | 1985-01-25 |
CS803483A2 (en) | 1984-12-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |