AT400298B - USE OF INJECTABLE, BIODEGRADABLE MICROBALLS, METHOD FOR THEIR PRODUCTION AND INJECTABLE SUSPENSIONS CONTAINING THE SAME - Google Patents

USE OF INJECTABLE, BIODEGRADABLE MICROBALLS, METHOD FOR THEIR PRODUCTION AND INJECTABLE SUSPENSIONS CONTAINING THE SAME

Info

Publication number
AT400298B
AT400298B AT0231390A AT231390A AT400298B AT 400298 B AT400298 B AT 400298B AT 0231390 A AT0231390 A AT 0231390A AT 231390 A AT231390 A AT 231390A AT 400298 B AT400298 B AT 400298B
Authority
AT
Austria
Prior art keywords
injectable
microballs
biodegradable
production
same
Prior art date
Application number
AT0231390A
Other languages
German (de)
Other versions
ATA231390A (en
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ATA231390A publication Critical patent/ATA231390A/en
Application granted granted Critical
Publication of AT400298B publication Critical patent/AT400298B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT0231390A 1989-11-15 1990-11-15 USE OF INJECTABLE, BIODEGRADABLE MICROBALLS, METHOD FOR THEIR PRODUCTION AND INJECTABLE SUSPENSIONS CONTAINING THE SAME AT400298B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR898914976A FR2654337B1 (en) 1989-11-15 1989-11-15 NOVEL BIODEGRADABLE INJECTABLE MICROSPHERES PREPARATION METHOD AND INJECTABLE SUSPENSIONS CONTAINING THEM.

Publications (2)

Publication Number Publication Date
ATA231390A ATA231390A (en) 1995-04-15
AT400298B true AT400298B (en) 1995-11-27

Family

ID=9387417

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0231390A AT400298B (en) 1989-11-15 1990-11-15 USE OF INJECTABLE, BIODEGRADABLE MICROBALLS, METHOD FOR THEIR PRODUCTION AND INJECTABLE SUSPENSIONS CONTAINING THE SAME

Country Status (13)

Country Link
JP (1) JPH03294229A (en)
AT (1) AT400298B (en)
BE (1) BE1005511A4 (en)
CA (1) CA2029940A1 (en)
CH (1) CH681691A5 (en)
DE (1) DE4036425A1 (en)
DK (1) DK270990A (en)
FR (1) FR2654337B1 (en)
GB (1) GB2239798B (en)
IT (1) IT1242010B (en)
LU (1) LU87836A1 (en)
NL (1) NL9002492A (en)
SE (1) SE9003570L (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222501B1 (en) * 1991-06-28 2003-07-28 Endorecherche Inc. Controlled release pharmaceutical composition containing mpa or mga and process for its preparation
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
ZA944377B (en) * 1993-06-24 1995-12-20 Lilly Co Eli Hypoglycemic agents
US5910492A (en) * 1995-06-05 1999-06-08 Takeda Chemical Industries, Ltd. Osteogenic promoting pharmaceutical composition
EP2210585A1 (en) 2009-01-16 2010-07-28 Exelgyn SPRM pharmaceutical compositions methods of treatment using them

Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2051580A1 (en) * 1969-10-23 1971-05-06 E I Du Pont de Nemours and Co, Wilmington, Del (V St A ) Polylactide drug mixtures
DE3136606A1 (en) * 1980-10-06 1982-06-16 Stolle Research & Development Corp., 45242 Cincinnatti, Ohio "METHOD FOR PRODUCING AN MICROCAPSULE CONTAINING AN ACTIVE SUBSTANCE AND THE MICROCAPSULES THEREFORE AVAILABLE
EP0057115A2 (en) * 1981-01-09 1982-08-04 Roussel-Uclaf Steroid derivatives substituted in the 11-beta position, process for their preparation, their utilization as medicaments and compositions containing them
EP0102265A2 (en) * 1982-07-29 1984-03-07 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
EP0129499A2 (en) * 1983-06-15 1984-12-27 Schering Aktiengesellschaft 13-Alpha-alkyl gonanes, their preparation and pharmaceutical compositions containing them
EP0138504A2 (en) * 1983-10-12 1985-04-24 Imperial Chemical Industries Plc Steroid derivatives
EP0147361A2 (en) * 1983-12-22 1985-07-03 Schering Aktiengesellschaft 11-Beta-aryl-estradienes, their preparation and pharmaceutical compositions containing them
GB2160873A (en) * 1984-06-29 1986-01-02 Roussel Uclaf 11B-(4-Aminophenyl) estra-4,9-dienes
EP0171907A1 (en) * 1984-07-06 1986-02-19 Wako Pure Chemical Industries, Ltd. Use of a copolymer in a controlled drug release composition
EP0184471A1 (en) * 1984-11-29 1986-06-11 Roussel-Uclaf Product containing an antiprogestomimetic and a uterotonic substance
US4652441A (en) * 1983-11-04 1987-03-24 Takeda Chemical Industries, Ltd. Prolonged release microcapsule and its production
EP0219447A2 (en) * 1985-09-13 1987-04-22 Schering Aktiengesellschaft Antigestagens for postponing endometrial maturation
WO1987005908A1 (en) * 1986-03-26 1987-10-08 Roussel-Uclaf Steroids comprising a spiranic cycle in position 17, preparation process and utilization thereof
EP0257369A1 (en) * 1986-08-11 1988-03-02 American Cyanamid Company Improved estradiol implant composition and method for preparation
EP0266303A2 (en) * 1986-09-26 1988-05-04 Schering Aktiengesellschaft Antigestagens for the inhibition of uterine prostaglandin synthesis
EP0310541A1 (en) * 1987-10-01 1989-04-05 Schering Aktiengesellschaft Antigestagenic and antioestrogenic compounds for the introduction of labour and interruption of pregnancy, as well as for the treatment of gynecologic disorders
EP0310542A1 (en) * 1987-10-01 1989-04-05 Schering Aktiengesellschaft Antigestagenic and antioestrogenic compounds for the treatment of hormone-dependent tumours
EP0322352A2 (en) * 1987-12-21 1989-06-28 Schering Aktiengesellschaft Use of anti-progestins for preparation of medicaments
GB2213484A (en) * 1987-12-30 1989-08-16 Roussel Uclaf New derivatives of 17beta-OH 19-nor steroids substituted in the 17 alpha position, and their use as medicaments

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
FR2528434B1 (en) * 1982-06-11 1985-07-19 Roussel Uclaf NOVEL 19-NOR STEROIDS SUBSTITUTED IN 11B AND POSSIBLY IN 2, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS A MEDICAMENT
FR2537980B1 (en) * 1982-12-17 1986-12-19 Sandoz Sa OLIGOMERIC HYDROXYCARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE
JP2670680B2 (en) * 1988-02-24 1997-10-29 株式会社ビーエムジー Polylactic acid microspheres containing physiologically active substance and method for producing the same

Patent Citations (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2051580A1 (en) * 1969-10-23 1971-05-06 E I Du Pont de Nemours and Co, Wilmington, Del (V St A ) Polylactide drug mixtures
DE3136606A1 (en) * 1980-10-06 1982-06-16 Stolle Research & Development Corp., 45242 Cincinnatti, Ohio "METHOD FOR PRODUCING AN MICROCAPSULE CONTAINING AN ACTIVE SUBSTANCE AND THE MICROCAPSULES THEREFORE AVAILABLE
EP0057115A2 (en) * 1981-01-09 1982-08-04 Roussel-Uclaf Steroid derivatives substituted in the 11-beta position, process for their preparation, their utilization as medicaments and compositions containing them
EP0102265A2 (en) * 1982-07-29 1984-03-07 The Stolle Research And Development Corporation Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
EP0129499A2 (en) * 1983-06-15 1984-12-27 Schering Aktiengesellschaft 13-Alpha-alkyl gonanes, their preparation and pharmaceutical compositions containing them
EP0138504A2 (en) * 1983-10-12 1985-04-24 Imperial Chemical Industries Plc Steroid derivatives
US4652441A (en) * 1983-11-04 1987-03-24 Takeda Chemical Industries, Ltd. Prolonged release microcapsule and its production
EP0147361A2 (en) * 1983-12-22 1985-07-03 Schering Aktiengesellschaft 11-Beta-aryl-estradienes, their preparation and pharmaceutical compositions containing them
GB2160873A (en) * 1984-06-29 1986-01-02 Roussel Uclaf 11B-(4-Aminophenyl) estra-4,9-dienes
EP0171907A1 (en) * 1984-07-06 1986-02-19 Wako Pure Chemical Industries, Ltd. Use of a copolymer in a controlled drug release composition
EP0184471A1 (en) * 1984-11-29 1986-06-11 Roussel-Uclaf Product containing an antiprogestomimetic and a uterotonic substance
EP0219447A2 (en) * 1985-09-13 1987-04-22 Schering Aktiengesellschaft Antigestagens for postponing endometrial maturation
WO1987005908A1 (en) * 1986-03-26 1987-10-08 Roussel-Uclaf Steroids comprising a spiranic cycle in position 17, preparation process and utilization thereof
EP0257369A1 (en) * 1986-08-11 1988-03-02 American Cyanamid Company Improved estradiol implant composition and method for preparation
EP0266303A2 (en) * 1986-09-26 1988-05-04 Schering Aktiengesellschaft Antigestagens for the inhibition of uterine prostaglandin synthesis
EP0310541A1 (en) * 1987-10-01 1989-04-05 Schering Aktiengesellschaft Antigestagenic and antioestrogenic compounds for the introduction of labour and interruption of pregnancy, as well as for the treatment of gynecologic disorders
EP0310542A1 (en) * 1987-10-01 1989-04-05 Schering Aktiengesellschaft Antigestagenic and antioestrogenic compounds for the treatment of hormone-dependent tumours
EP0322352A2 (en) * 1987-12-21 1989-06-28 Schering Aktiengesellschaft Use of anti-progestins for preparation of medicaments
GB2213484A (en) * 1987-12-30 1989-08-16 Roussel Uclaf New derivatives of 17beta-OH 19-nor steroids substituted in the 17 alpha position, and their use as medicaments

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS 100, 45 474 G (1984) *
CHEMICAL ABSTRACTS 104, 10 476 Q (1986) *
CHEMICAL ABSTRACTS 98, 149 537 M (1983) *

Also Published As

Publication number Publication date
ATA231390A (en) 1995-04-15
FR2654337A1 (en) 1991-05-17
GB2239798A (en) 1991-07-17
GB9024862D0 (en) 1991-01-02
IT1242010B (en) 1994-02-02
LU87836A1 (en) 1991-05-07
SE9003570D0 (en) 1990-11-09
IT9048470A0 (en) 1990-11-13
BE1005511A4 (en) 1993-08-31
GB2239798B (en) 1993-10-27
SE9003570L (en) 1991-05-16
NL9002492A (en) 1991-06-03
DK270990A (en) 1991-05-16
JPH03294229A (en) 1991-12-25
CA2029940A1 (en) 1991-05-16
DK270990D0 (en) 1990-11-13
FR2654337B1 (en) 1994-08-05
CH681691A5 (en) 1993-05-14
DE4036425A1 (en) 1991-05-16
IT9048470A1 (en) 1992-05-13

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Legal Events

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ELJ Ceased due to non-payment of the annual fee