AT379815B - Verfahren zur herstellung von (e)-5(2-bromvinyl)- uridins und seiner derivate - Google Patents
Verfahren zur herstellung von (e)-5(2-bromvinyl)- uridins und seiner derivateInfo
- Publication number
- AT379815B AT379815B AT0333882A AT333882A AT379815B AT 379815 B AT379815 B AT 379815B AT 0333882 A AT0333882 A AT 0333882A AT 333882 A AT333882 A AT 333882A AT 379815 B AT379815 B AT 379815B
- Authority
- AT
- Austria
- Prior art keywords
- uridins
- bromvinyl
- derivatives
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU812571A HU183567B (en) | 1981-09-07 | 1981-09-07 | Process for preparing /e/-5-/2-bromo-vinyl/-uridine and derivatives thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA333882A ATA333882A (de) | 1985-07-15 |
AT379815B true AT379815B (de) | 1986-03-10 |
Family
ID=10960052
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0333882A AT379815B (de) | 1981-09-07 | 1982-09-07 | Verfahren zur herstellung von (e)-5(2-bromvinyl)- uridins und seiner derivate |
Country Status (15)
Country | Link |
---|---|
US (1) | US4544740A (de) |
JP (1) | JPS5888398A (de) |
AT (1) | AT379815B (de) |
BE (1) | BE894294A (de) |
CA (1) | CA1207760A (de) |
CH (1) | CH653340A5 (de) |
CS (1) | CS228939B2 (de) |
DE (1) | DE3233198A1 (de) |
FR (1) | FR2513252A1 (de) |
GB (1) | GB2106107B (de) |
HU (1) | HU183567B (de) |
NL (1) | NL8203476A (de) |
PL (1) | PL137818B1 (de) |
SE (1) | SE8205056L (de) |
SU (1) | SU1240363A3 (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU187736B (en) * | 1982-08-04 | 1986-02-28 | Mta Koezponti Kemiai Kutato Intezet,Hu | Process for producing /e/ -5-/2-bromovinyl/-2-comma above-deoxyuridine and o-acyl derivatives |
FR2531962B1 (fr) * | 1982-08-17 | 1986-11-14 | Sandoz Sa | Nouveaux derives de la desoxyuridine, leur preparation et leur utilisation comme medicaments |
AU575022B2 (en) * | 1982-09-17 | 1988-07-21 | Glaxo Group Limited | Antiviral 5-halovinyl-2'-deoxyuridines |
US4658044A (en) * | 1983-09-16 | 1987-04-14 | Glaxo Group Limited | Intermediates for uracil derivatives |
GB8517402D0 (en) * | 1985-07-10 | 1985-08-14 | Wellcome Found | Treatment of viral infections |
GB8912972D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Therapeutic nucleosides |
US5446031A (en) * | 1991-04-24 | 1995-08-29 | Yamasa Shuyu Kabushiki Kaisha | 1-β-D-arabinofuranosyl-(E)-5-(2-halogenovinyl)uracil derivatives |
DE102006037786A1 (de) | 2006-08-11 | 2008-03-20 | Resprotect Gmbh | Nukleoside, diese enthaltendes Arzneimittel und deren Verwendung |
AU2009223453B2 (en) | 2008-03-03 | 2014-05-01 | Tosk, Inc. | Methotrexate adjuvants to reduce toxicity and methods for using the same |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3002197A1 (de) * | 1980-01-22 | 1981-07-23 | Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen | 5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1601020A (en) * | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
US4247544A (en) * | 1979-07-02 | 1981-01-27 | The Regents Of The University Of California | C-5 Substituted uracil nucleosides |
GB2060604B (en) * | 1979-10-03 | 1983-11-23 | Univ Birmingham And Stichting | E15-(2-halogenovinyl)-2'-deoxycytidines |
JPS5687599A (en) * | 1979-12-19 | 1981-07-16 | Yamasa Shoyu Co Ltd | E 55 22halogenovinyl arabinofuranosyluracil and its preparation |
EP0060099A1 (de) * | 1981-03-11 | 1982-09-15 | Beecham Group Plc | Antivirale Verbindungen, ihre Herstellung und Verwendung |
NZ199764A (en) * | 1981-03-20 | 1984-08-24 | Beecham Group Plc | 5-(2-halogenovinyl)-2'-deoxyuridine derivatives and pharmaceutical compositions |
-
1981
- 1981-09-07 HU HU812571A patent/HU183567B/hu not_active IP Right Cessation
-
1982
- 1982-09-02 CS CS826394A patent/CS228939B2/cs unknown
- 1982-09-03 BE BE1/10586A patent/BE894294A/fr not_active IP Right Cessation
- 1982-09-06 PL PL1982238159A patent/PL137818B1/pl unknown
- 1982-09-06 CH CH5283/82A patent/CH653340A5/de not_active IP Right Cessation
- 1982-09-06 FR FR8215107A patent/FR2513252A1/fr active Granted
- 1982-09-06 SE SE8205056A patent/SE8205056L/xx not_active Application Discontinuation
- 1982-09-07 GB GB08225488A patent/GB2106107B/en not_active Expired
- 1982-09-07 AT AT0333882A patent/AT379815B/de not_active IP Right Cessation
- 1982-09-07 US US06/415,424 patent/US4544740A/en not_active Expired - Fee Related
- 1982-09-07 JP JP57154750A patent/JPS5888398A/ja active Pending
- 1982-09-07 SU SU823491621A patent/SU1240363A3/ru active
- 1982-09-07 NL NL8203476A patent/NL8203476A/nl not_active Application Discontinuation
- 1982-09-07 CA CA000410918A patent/CA1207760A/en not_active Expired
- 1982-09-07 DE DE19823233198 patent/DE3233198A1/de not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3002197A1 (de) * | 1980-01-22 | 1981-07-23 | Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen | 5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel |
Also Published As
Publication number | Publication date |
---|---|
SU1240363A3 (ru) | 1986-06-23 |
CH653340A5 (de) | 1985-12-31 |
CS228939B2 (en) | 1984-05-14 |
US4544740A (en) | 1985-10-01 |
GB2106107B (en) | 1985-06-12 |
FR2513252B1 (de) | 1985-02-15 |
HU183567B (en) | 1984-05-28 |
GB2106107A (en) | 1983-04-07 |
DE3233198A1 (de) | 1983-03-17 |
NL8203476A (nl) | 1983-04-05 |
JPS5888398A (ja) | 1983-05-26 |
BE894294A (fr) | 1983-03-03 |
ATA333882A (de) | 1985-07-15 |
SE8205056L (sv) | 1983-03-08 |
CA1207760A (en) | 1986-07-15 |
PL238159A1 (en) | 1984-02-13 |
PL137818B1 (en) | 1986-07-31 |
SE8205056D0 (sv) | 1982-09-06 |
FR2513252A1 (fr) | 1983-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee | ||
ELJ | Ceased due to non-payment of the annual fee |