AT370728B - Verfahren zur herstellung von pyrimidinverbindungen und von deren salzen - Google Patents

Verfahren zur herstellung von pyrimidinverbindungen und von deren salzen

Info

Publication number
AT370728B
AT370728B AT0492279A AT492279A AT370728B AT 370728 B AT370728 B AT 370728B AT 0492279 A AT0492279 A AT 0492279A AT 492279 A AT492279 A AT 492279A AT 370728 B AT370728 B AT 370728B
Authority
AT
Austria
Prior art keywords
salts
pyrimidine compounds
producing pyrimidine
producing
compounds
Prior art date
Application number
AT0492279A
Other languages
English (en)
Other versions
ATA492279A (de
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of ATA492279A publication Critical patent/ATA492279A/de
Application granted granted Critical
Publication of AT370728B publication Critical patent/AT370728B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0492279A 1978-07-15 1979-07-16 Verfahren zur herstellung von pyrimidinverbindungen und von deren salzen AT370728B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7829999 1978-07-15

Publications (2)

Publication Number Publication Date
ATA492279A ATA492279A (de) 1982-09-15
AT370728B true AT370728B (de) 1983-04-25

Family

ID=10498456

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0492279A AT370728B (de) 1978-07-15 1979-07-16 Verfahren zur herstellung von pyrimidinverbindungen und von deren salzen

Country Status (20)

Country Link
US (4) US4305945A (de)
EP (1) EP0007232A1 (de)
JP (1) JPS5515499A (de)
KR (1) KR830001247A (de)
AR (1) AR226420A1 (de)
AT (1) AT370728B (de)
AU (1) AU528878B2 (de)
CA (1) CA1114375A (de)
DD (1) DD144916A5 (de)
DK (1) DK293079A (de)
ES (1) ES482448A1 (de)
FI (1) FI792220A (de)
GR (1) GR69252B (de)
IL (1) IL57790A (de)
NO (1) NO792337L (de)
NZ (1) NZ191006A (de)
PH (1) PH15979A (de)
PL (1) PL217121A1 (de)
PT (1) PT69886A (de)
ZA (1) ZA793392B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN151188B (de) * 1978-02-13 1983-03-05 Smith Kline French Lab
PH16240A (en) * 1978-04-11 1983-08-11 Smith Kline French Lab Process for making histamine antagonist
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas
DK558181A (da) * 1981-01-30 1982-07-31 Smithkline Corp Fremgangsmaade til fremstilling af 3,5-diamino-1,2,4-triazoler
US4477663A (en) * 1981-02-06 1984-10-16 Smithkline Beckman Corporation Intermediates for preparing substituted pyrimidinones
US4620001A (en) * 1981-02-06 1986-10-28 Smithkline Beckman Corporation Chemical methods and intermediates for preparing substituted pyrimidinones
JPH0641454B2 (ja) * 1985-02-27 1994-06-01 日産化学工業株式会社 ピリダジノン誘導体
DE3532880A1 (de) * 1985-09-14 1987-03-26 Basf Ag 1,4-disubstituierte pyrazolderivate
EP4196793A1 (de) 2020-08-11 2023-06-21 Université de Strasbourg Auf lebermakrophagen abzielende h2-blocker zur prävention und behandlung von lebererkrankungen und krebs

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1223686A (en) 1967-02-24 1971-03-03 Ici Ltd Salts of pyrimidine derivatives and the use thereof as fungicides
US3980781A (en) * 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
GB1419994A (en) * 1973-05-03 1976-01-07 Smith Kline French Lab Heterocyclicalkylaminotheterocyclic compounds methods for their preparation and compositions comprising them
US4218452A (en) * 1975-10-02 1980-08-19 Smith Kline & French Laboratories Limited Substituted 4-pyrimidone compounds, compositions and methods of use
US4145546A (en) * 1975-10-02 1979-03-20 Smith Kline & French Laboratories Limited 4-Pyrimidone compounds
GB1578219A (en) * 1975-12-01 1980-11-05 Smith Kline French Lab Isothioureas
MW5076A1 (en) * 1975-12-29 1978-02-08 Smith Kline French Lab Pharmacologicalle active compounds
US4154834A (en) * 1975-12-29 1979-05-15 Smith Kline & French Laboratories Limited Substituted isocytosines having histamine H2 -antagonist activity
IN151188B (de) * 1978-02-13 1983-03-05 Smith Kline French Lab
ZA793392B (en) * 1978-07-15 1980-08-27 Smith Kline French Lab Isoureas and isothioureas

Also Published As

Publication number Publication date
AR226420A1 (es) 1982-07-15
AU528878B2 (en) 1983-05-19
NZ191006A (en) 1982-09-07
US4305945A (en) 1981-12-15
ZA793392B (en) 1980-08-27
GR69252B (de) 1982-05-11
JPS5515499A (en) 1980-02-02
IL57790A0 (en) 1979-11-30
US4439435A (en) 1984-03-27
AU4895479A (en) 1980-01-24
PL217121A1 (de) 1980-06-16
ES482448A1 (es) 1980-04-01
IL57790A (en) 1984-01-31
KR830001247A (ko) 1983-04-29
US4639519A (en) 1987-01-27
US4558128A (en) 1985-12-10
DK293079A (da) 1980-01-16
FI792220A (fi) 1980-01-16
NO792337L (no) 1980-01-16
PT69886A (en) 1979-08-01
DD144916A5 (de) 1980-11-12
EP0007232A1 (de) 1980-01-23
CA1114375A (en) 1981-12-15
PH15979A (en) 1983-05-16
ATA492279A (de) 1982-09-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee