AT364831B - Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen - Google Patents

Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Info

Publication number
AT364831B
AT364831B AT0582978A AT582978A AT364831B AT 364831 B AT364831 B AT 364831B AT 0582978 A AT0582978 A AT 0582978A AT 582978 A AT582978 A AT 582978A AT 364831 B AT364831 B AT 364831B
Authority
AT
Austria
Prior art keywords
razemats
hydroxy
salts
optically active
active forms
Prior art date
Application number
AT0582978A
Other languages
English (en)
Other versions
ATA582978A (de
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19782801953 external-priority patent/DE2801953A1/de
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Priority to AT556180A priority Critical patent/AT375650B/de
Publication of ATA582978A publication Critical patent/ATA582978A/de
Application granted granted Critical
Publication of AT364831B publication Critical patent/AT364831B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT0582978A 1977-08-12 1978-08-10 Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen AT364831B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT556180A AT375650B (de) 1977-08-12 1980-11-12 Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2736295 1977-08-12
DE19782801953 DE2801953A1 (de) 1978-01-18 1978-01-18 4-hydroxy-2-benzimidazolinon-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ATA582978A ATA582978A (de) 1981-04-15
AT364831B true AT364831B (de) 1981-11-25

Family

ID=25772515

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0582978A AT364831B (de) 1977-08-12 1978-08-10 Verfahren zur herstellung von neuen 4-hydroxy-2 -benzimidazolinon-derivaten und von deren salzen, razematen und optisch aktiven formen

Country Status (14)

Country Link
US (1) US4367235A (de)
EP (1) EP0000784B1 (de)
JP (1) JPS5432467A (de)
AT (1) AT364831B (de)
AU (1) AU3888578A (de)
CA (1) CA1108619A (de)
DD (1) DD137584A5 (de)
DE (1) DE2860981D1 (de)
DK (1) DK355378A (de)
ES (1) ES472435A1 (de)
FI (1) FI782452A (de)
IL (1) IL55315A0 (de)
IT (1) IT7826640A0 (de)
PT (1) PT68404A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0178413A1 (de) * 1984-08-17 1986-04-23 Beecham Group Plc Benzimidazole
US4554287A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones
JPS63156809A (ja) * 1986-12-19 1988-06-29 Shin Etsu Chem Co Ltd 塩化ビニル系重合体の製造方法
CA2085844A1 (en) * 1991-12-27 1993-06-28 Nobuyuki Hamanaka Fused benzeneoxyacetic acid derivatives
JPH09502166A (ja) * 1993-07-31 1997-03-04 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー アドレナリン受容体作動薬活性を有する２−ベンゾヘテロシクリルオキシまたはチオプロパノールアミン誘導体
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US5808080A (en) * 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
EP0827746B1 (de) 1996-09-05 2002-04-03 Eli Lilly And Company Carbazolanaloge als selektive beta3-adrenergische Agonisten
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
CN103445428A (zh) * 2012-05-28 2013-12-18 苏州科羽电子技术服务有限公司 一种车座手提袋

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (de) * 1976-01-08 1981-07-31 Ciba Geigy Ag

Also Published As

Publication number Publication date
PT68404A (de) 1978-09-01
JPS5432467A (en) 1979-03-09
DK355378A (da) 1979-02-13
EP0000784A1 (de) 1979-02-21
IT7826640A0 (it) 1978-08-09
DD137584A5 (de) 1979-09-12
IL55315A0 (en) 1978-10-31
DE2860981D1 (en) 1981-11-19
AU3888578A (en) 1980-02-21
ES472435A1 (es) 1979-04-16
CA1108619A (en) 1981-09-08
FI782452A (fi) 1979-02-13
ATA582978A (de) 1981-04-15
US4367235A (en) 1983-01-04
EP0000784B1 (de) 1981-08-26

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee