AT360663B - Verfahren zur herstellung von neuen 6,7- -benzomorphanen - Google Patents
Verfahren zur herstellung von neuen 6,7- -benzomorphanenInfo
- Publication number
- AT360663B AT360663B AT137276A AT137276A AT360663B AT 360663 B AT360663 B AT 360663B AT 137276 A AT137276 A AT 137276A AT 137276 A AT137276 A AT 137276A AT 360663 B AT360663 B AT 360663B
- Authority
- AT
- Austria
- Prior art keywords
- benzomorphans
- producing new
- producing
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- One-Way And Automatic Clutches, And Combinations Of Different Clutches (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7891/75A GB1513961A (en) | 1975-02-25 | 1975-02-25 | 6,7-benzomorphans method for their preparation and intermediates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA137276A ATA137276A (de) | 1980-06-15 |
| AT360663B true AT360663B (de) | 1981-01-26 |
Family
ID=9841801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT137276A AT360663B (de) | 1975-02-25 | 1976-02-25 | Verfahren zur herstellung von neuen 6,7- -benzomorphanen |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US4128548A (de) |
| JP (2) | JPS51111550A (de) |
| AT (1) | AT360663B (de) |
| AU (1) | AU505939B2 (de) |
| BE (1) | BE838708A (de) |
| CA (1) | CA1080704A (de) |
| CH (2) | CH621115A5 (de) |
| DE (1) | DE2606267A1 (de) |
| DK (1) | DK76176A (de) |
| ES (1) | ES445494A1 (de) |
| FR (1) | FR2302092A1 (de) |
| GB (1) | GB1513961A (de) |
| HU (1) | HU173571B (de) |
| IE (1) | IE43450B1 (de) |
| IL (1) | IL48990A (de) |
| IT (1) | IT1057250B (de) |
| LU (1) | LU74431A1 (de) |
| NL (1) | NL7601924A (de) |
| PH (1) | PH12974A (de) |
| SE (1) | SE7602235L (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5381778A (en) * | 1976-12-27 | 1978-07-19 | Toshiharu Nakao | Cloth loop forming apparatus in steaming apparatus |
| NL7804509A (nl) * | 1978-04-26 | 1979-10-30 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan. |
| DE2828039A1 (de) * | 1978-06-26 | 1980-01-10 | Boehringer Sohn Ingelheim | 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung |
| US4208523A (en) * | 1978-11-30 | 1980-06-17 | Sterling Drug Inc. | 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines |
| NL7907800A (nl) * | 1979-10-23 | 1981-04-27 | Acf Chemiefarma Nv | Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten. |
| US5490436A (en) * | 1994-03-17 | 1996-02-13 | At&T Corp. | Liquid-chamber apparatus for active, dynamic balancing of rotating machinery |
| EP2987788A1 (de) | 2002-05-17 | 2016-02-24 | Taiwanj Pharmaceuticals Co., Ltd. | Opioid und opioidähnliche verbindungen und verwendung davon |
| US7501433B2 (en) * | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7923454B2 (en) * | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| ATE554078T1 (de) * | 2007-07-26 | 2012-05-15 | Vitae Pharmaceuticals Inc | Synthese von 11-beta-hydroxysteroid-dehydrogenase-1-hemmern |
| AR069207A1 (es) * | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1 |
| CL2008003407A1 (es) * | 2007-11-16 | 2010-01-11 | Boehringer Ingelheim Int | Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1. |
| WO2009075835A1 (en) | 2007-12-11 | 2009-06-18 | Vitae Pharmaceutical, Inc | CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1 |
| TW200934490A (en) * | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| EP2245014B1 (de) * | 2008-02-12 | 2011-11-02 | Boehringer Ingelheim International GmbH | Harnstoff-derivate von benzomorphanen, entsprechende gerüste, medikamente mit solchen verbindungen und ihre verwendung |
| AR071609A1 (es) | 2008-05-01 | 2010-06-30 | Vitae Pharmaceuticals Inc | Inhibidores ciclicos de 11(beta) -hidroxiesteroide deshidrogenasa 1 |
| CL2009001151A1 (es) | 2008-05-13 | 2010-08-13 | Boehringer Ingelheim Int | Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos. |
| WO2010010157A2 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
| CA2730499A1 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| MA33216B1 (fr) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1 |
| EP2438049B1 (de) | 2009-06-02 | 2014-05-14 | Boehringer Ingelheim International GmbH | Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1 |
| EP2440537A1 (de) | 2009-06-11 | 2012-04-18 | Vitae Pharmaceuticals, Inc. | Cyclische hemmer der 11beta-hydroxysteroiddehydrogenase 1 auf basis der 1,3 -oxazinan- 2 -on-struktur |
| JP5456555B2 (ja) | 2010-04-23 | 2014-04-02 | 株式会社マキタ | 電動工具 |
| EP2582698B1 (de) | 2010-06-16 | 2016-09-14 | Vitae Pharmaceuticals, Inc. | Substituierte 5-,6- und 7-gliedrige heterocyclen, medikamente mit derartigen verbindungen und ihre verwendung |
| EP2585444B1 (de) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanone als 11-beta-hsd1-hemmer zur behandlung von stoffwechselerkrankungen |
| WO2012059416A1 (en) | 2010-11-02 | 2012-05-10 | Boehringer Ingelheim International Gmbh | Pharmaceutical combinations for the treatment of metabolic disorders |
| WO2013025664A1 (en) | 2011-08-17 | 2013-02-21 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3138603A (en) * | 1958-10-31 | 1964-06-23 | Everette L May | New benzomorphans (methanobenzazocines) and preparation thereof |
| US3372165A (en) * | 1960-12-01 | 1968-03-05 | Sterling Drug Inc | 1, 2, 3, 4, 5, 6-hexahydro-8-hydroxy-2, 6-methano-3-benzazocine derivatives |
| NL156047B (nl) * | 1969-06-04 | 1978-03-15 | Acf Chemiefarma Nv | Werkwijze voor de bereiding van farmaceutische preparaten met analgetische en/of morfine-antagonistische werking, gevormde preparaten, alsmede werkwijze voor de bereiding van daartoe geschikte nieuwe 6,7-benzomorfanen. |
| IE34235B1 (en) * | 1969-06-04 | 1975-03-19 | Acf Chemiefarma Nv | 6,7-benzomorphans and their preparation |
| CA1010031A (en) * | 1972-10-31 | 1977-05-10 | Kentaro Tamaki | 6,7-benzomorphan derivatives |
| US4010164A (en) * | 1973-03-28 | 1977-03-01 | Boehringer Ingelheim Gmbh | N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof |
| SU511005A3 (ru) * | 1973-10-27 | 1976-04-15 | К.Х.Берингер Зон., (Фирма) | Способ получени (метоксиметилфурилметил)6,7-бензоморфанов или морфинанов |
| US4087532A (en) * | 1974-03-09 | 1978-05-02 | Boehringer Ingelheim Gmbh | Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof |
| US4032529A (en) * | 1974-09-20 | 1977-06-28 | Sterling Drug Inc. | Aminomethanobenzazocine intermediates |
-
1975
- 1975-02-25 GB GB7891/75A patent/GB1513961A/en not_active Expired
-
1976
- 1976-02-05 AU AU10856/76A patent/AU505939B2/en not_active Expired
- 1976-02-09 IL IL48990A patent/IL48990A/xx unknown
- 1976-02-17 DE DE19762606267 patent/DE2606267A1/de not_active Withdrawn
- 1976-02-17 US US05/658,739 patent/US4128548A/en not_active Expired - Lifetime
- 1976-02-19 BE BE164433A patent/BE838708A/xx unknown
- 1976-02-20 IE IE334/76A patent/IE43450B1/en unknown
- 1976-02-23 PH PH18131A patent/PH12974A/en unknown
- 1976-02-23 JP JP1875676A patent/JPS51111550A/ja active Pending
- 1976-02-24 DK DK76176*#A patent/DK76176A/da unknown
- 1976-02-24 ES ES445494A patent/ES445494A1/es not_active Expired
- 1976-02-24 FR FR7605083A patent/FR2302092A1/fr active Granted
- 1976-02-24 SE SE7602235A patent/SE7602235L/xx not_active Application Discontinuation
- 1976-02-24 IT IT67415/76A patent/IT1057250B/it active
- 1976-02-25 LU LU74431A patent/LU74431A1/xx unknown
- 1976-02-25 NL NL7601924A patent/NL7601924A/xx not_active Application Discontinuation
- 1976-02-25 AT AT137276A patent/AT360663B/de not_active IP Right Cessation
- 1976-02-25 CA CA246,540A patent/CA1080704A/en not_active Expired
- 1976-02-25 JP JP51019022A patent/JPS51118767A/ja active Pending
- 1976-02-25 HU HU76CE1075A patent/HU173571B/hu unknown
- 1976-02-25 CH CH234376A patent/CH621115A5/de not_active IP Right Cessation
-
1978
- 1978-07-28 US US05/928,862 patent/US4268673A/en not_active Expired - Lifetime
-
1979
- 1979-11-20 CH CH1036579A patent/CH623572A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CH623572A5 (de) | 1981-06-15 |
| US4268673A (en) | 1981-05-19 |
| SE7602235L (sv) | 1976-08-26 |
| DK76176A (da) | 1976-08-26 |
| DE2606267A1 (de) | 1976-09-30 |
| PH12974A (en) | 1979-10-24 |
| CA1080704A (en) | 1980-07-01 |
| NL7601924A (nl) | 1976-08-27 |
| JPS51118767A (en) | 1976-10-18 |
| HU173571B (hu) | 1979-06-28 |
| IE43450L (en) | 1976-08-25 |
| LU74431A1 (de) | 1976-08-13 |
| AU1085676A (en) | 1977-08-11 |
| GB1513961A (en) | 1978-06-14 |
| BE838708A (fr) | 1976-08-19 |
| IL48990A0 (en) | 1976-04-30 |
| IT1057250B (it) | 1982-03-10 |
| JPS51111550A (en) | 1976-10-01 |
| CH621115A5 (de) | 1981-01-15 |
| ES445494A1 (es) | 1977-11-01 |
| FR2302092A1 (fr) | 1976-09-24 |
| US4128548A (en) | 1978-12-05 |
| IL48990A (en) | 1980-01-31 |
| IE43450B1 (en) | 1981-02-25 |
| FR2302092B1 (de) | 1978-11-10 |
| ATA137276A (de) | 1980-06-15 |
| AU505939B2 (en) | 1979-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |