AT350530B - Verfahren zur herstellung von racemischen oder optisch aktiven monoaminocarbonsaeurealkyl- oder -aralkylestern - Google Patents

Verfahren zur herstellung von racemischen oder optisch aktiven monoaminocarbonsaeurealkyl- oder -aralkylestern

Info

Publication number
AT350530B
AT350530B AT480475A AT480475A AT350530B AT 350530 B AT350530 B AT 350530B AT 480475 A AT480475 A AT 480475A AT 480475 A AT480475 A AT 480475A AT 350530 B AT350530 B AT 350530B
Authority
AT
Austria
Prior art keywords
monoaminocarbonic
optically active
acid alkyl
aralkyl esters
producing racemic
Prior art date
Application number
AT480475A
Other languages
English (en)
Other versions
ATA480475A (de
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ATA480475A publication Critical patent/ATA480475A/de
Application granted granted Critical
Publication of AT350530B publication Critical patent/AT350530B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
AT480475A 1974-06-25 1975-06-23 Verfahren zur herstellung von racemischen oder optisch aktiven monoaminocarbonsaeurealkyl- oder -aralkylestern AT350530B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/482,103 US3988341A (en) 1974-06-25 1974-06-25 Esterification process

Publications (2)

Publication Number Publication Date
ATA480475A ATA480475A (de) 1978-11-15
AT350530B true AT350530B (de) 1979-06-11

Family

ID=23914672

Family Applications (1)

Application Number Title Priority Date Filing Date
AT480475A AT350530B (de) 1974-06-25 1975-06-23 Verfahren zur herstellung von racemischen oder optisch aktiven monoaminocarbonsaeurealkyl- oder -aralkylestern

Country Status (21)

Country Link
US (1) US3988341A (de)
JP (1) JPS5921862B2 (de)
AR (1) AR216740A1 (de)
AT (1) AT350530B (de)
CA (1) CA1064958A (de)
CH (1) CH613184A5 (de)
DE (1) DE2528069C3 (de)
DK (1) DK147938C (de)
ES (1) ES438764A1 (de)
FI (1) FI61870C (de)
FR (1) FR2276291A1 (de)
GB (1) GB1464328A (de)
HK (1) HK6780A (de)
HU (1) HU172841B (de)
IE (1) IE41482B1 (de)
NL (1) NL7506958A (de)
NO (1) NO144567C (de)
PL (1) PL98343B1 (de)
SE (1) SE436353B (de)
YU (1) YU39533B (de)
ZA (1) ZA754041B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058530A (en) * 1973-09-25 1977-11-15 Merck & Co., Inc. Amino acid esters
US4156734A (en) * 1976-02-13 1979-05-29 Merck & Co., Inc. Antihypertensive compositions containing an aryl-substituted alanine azo and an arylhydrazino-propionic acid
US4065572A (en) * 1976-02-13 1977-12-27 Merck & Co., Inc. Amino acids and esters thereof useful as antihypertensive agents
US4143146A (en) * 1976-03-18 1979-03-06 Merck & Co., Inc. Esters of α-methyl-3,4-OR-phenylalanines
FR2499076A1 (fr) * 1981-02-02 1982-08-06 Panmedica Laboratoires Nouveaux derives de l'acide ((indol-3 yl)-3 amino-2 propionyloxy)-2 acetique, procedes pour leur preparation et medicaments les contenant
US4404392A (en) * 1981-11-16 1983-09-13 Merck & Co., Inc. Resolution of α-pivaloyloxyethyl-(S)-3-(3,4-dihydroxyphenyl)-2-methylalantinate into its α and β isomers
US4440942A (en) * 1982-03-01 1984-04-03 Merck & Co., Inc. Crystalline diastereomeric L-alpha-methyldopa POE ester and process for its preparation
US4670578A (en) * 1983-08-29 1987-06-02 Merck & Co., Inc. Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters
JPS612047U (ja) * 1984-06-12 1986-01-08 九州積水工業株式会社 海苔網の干出及び張設用支持杆
DE3925847A1 (de) * 1989-08-04 1991-02-07 Huels Chemische Werke Ag Verfahren zur herstellung von 3-aminopyrazin-2-carbonsaeuremethylester
US5374765A (en) * 1990-09-03 1994-12-20 Mitsui Toatsu Chemicals, Incorporated Method for extracting an amino acid ester from a hydrous solution of a mineral acid salt thereof
JP2923009B2 (ja) * 1990-09-03 1999-07-26 三井化学株式会社 アミノ酸エステルの抽出方法
EP0593559A1 (de) * 1991-07-05 1994-04-27 MERCK SHARP & DOHME LTD. Aromatische verbindungen, diese enthaltende arzneimittel und ihre therapeutische verwendung
US5328927A (en) * 1992-03-03 1994-07-12 Merck Sharpe & Dohme, Ltd. Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
US5659065A (en) * 1994-04-18 1997-08-19 Novartis Corporation Alpha-aminoalkanoic acids and reduction products

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH379523A (de) * 1959-02-20 1964-07-15 Bracco Ind Chimica Societa Azi Verfahren zur Überführung von racemischem Serinmethylester in hinsichtlich der optischen Isomerie reine Serinmethylester-tartrate
US3510500A (en) * 1963-12-26 1970-05-05 Gulf Research Development Co Process for preparing an ester from a monobasic organic acid and an organic halide
GB1051322A (de) * 1967-08-09

Also Published As

Publication number Publication date
ES438764A1 (es) 1977-07-01
NO144567B (no) 1981-06-15
JPS5921862B2 (ja) 1984-05-22
DK147938C (da) 1985-09-02
PL98343B1 (pl) 1978-04-29
YU158075A (en) 1983-01-21
CH613184A5 (de) 1979-09-14
IE41482L (en) 1975-12-25
DK263675A (da) 1975-12-26
CA1064958A (en) 1979-10-23
DK147938B (da) 1985-01-14
DE2528069B2 (de) 1979-10-11
DE2528069A1 (de) 1976-01-08
JPS5126802A (de) 1976-03-05
SE436353B (sv) 1984-12-03
AR216740A1 (es) 1980-01-31
NO144567C (no) 1981-09-23
AU8221775A (en) 1976-12-23
FI61870B (fi) 1982-06-30
YU39533B (en) 1984-12-31
HK6780A (en) 1980-03-07
SE7506730L (sv) 1975-12-29
ZA754041B (en) 1977-01-26
FI61870C (fi) 1982-10-11
HU172841B (hu) 1978-12-28
ATA480475A (de) 1978-11-15
IE41482B1 (en) 1980-01-16
FR2276291B1 (de) 1978-12-08
US3988341A (en) 1976-10-26
FR2276291A1 (fr) 1976-01-23
DE2528069C3 (de) 1980-06-19
NL7506958A (nl) 1975-12-30
NO752090L (de) 1975-12-30
FI751729A (de) 1975-12-26
GB1464328A (en) 1977-02-09

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee