AT347477B - Verfahren zur herstellung von 1-(2- tetrahydrofuryl)-5-fluorouracil - Google Patents
Verfahren zur herstellung von 1-(2- tetrahydrofuryl)-5-fluorouracilInfo
- Publication number
- AT347477B AT347477B AT961176A AT961176A AT347477B AT 347477 B AT347477 B AT 347477B AT 961176 A AT961176 A AT 961176A AT 961176 A AT961176 A AT 961176A AT 347477 B AT347477 B AT 347477B
- Authority
- AT
- Austria
- Prior art keywords
- tetrahydrofuryl
- fluorouracil
- producing
- Prior art date
Links
- WFWLQNSHRPWKFK-UHFFFAOYSA-N Tegafur Chemical compound O=C1NC(=O)C(F)=CN1C1OCCC1 WFWLQNSHRPWKFK-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15340375A JPS5943471B2 (ja) | 1975-12-24 | 1975-12-24 | １−（２− テトラヒドロフリル ）−５− フルオロウラシルノセイゾウホウ |
| JP160076A JPS5289678A (en) | 1976-01-09 | 1976-01-09 | Preparation of 1-(2-tetrahydrofuryl)-5-fluorouracil |
| JP540876A JPS5289680A (en) | 1976-01-22 | 1976-01-22 | Preparation of 1-(2-tetrahydrofuryl)-5-flurouracil |
| JP5725576A JPS52142079A (en) | 1976-05-20 | 1976-05-20 | Preparation of 1-(2-tetrahydrofuryl)-5-flurouracil |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA961176A ATA961176A (de) | 1978-05-15 |
| AT347477B true AT347477B (de) | 1978-12-27 |
Family
ID=27453446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT961176A AT347477B (de) | 1975-12-24 | 1976-12-23 | Verfahren zur herstellung von 1-(2- tetrahydrofuryl)-5-fluorouracil |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4256885A (de) |
| AT (1) | AT347477B (de) |
| CA (1) | CA1114376A (de) |
| CH (1) | CH623583A5 (de) |
| DE (1) | DE2656604C3 (de) |
| DK (1) | DK142415B (de) |
| FI (1) | FI63758C (de) |
| FR (1) | FR2336401A1 (de) |
| GB (1) | GB1522860A (de) |
| NL (1) | NL7614220A (de) |
| NO (1) | NO145575C (de) |
| PH (1) | PH15812A (de) |
| PT (1) | PT66013B (de) |
| SE (1) | SE7613751L (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102285972A (zh) * | 2011-08-08 | 2011-12-21 | 江苏大学 | 一种制备替加氟的方法 |
| CN103159746B (zh) * | 2011-12-12 | 2015-09-02 | 山东新时代药业有限公司 | 一种工业法合成替加氟的方法 |
| CN106397416B (zh) * | 2016-09-05 | 2019-05-17 | 深圳万乐药业有限公司 | 一种替加氟的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3960864A (en) * | 1974-05-06 | 1976-06-01 | The University Of Utah | Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil |
| JPS5259174A (en) * | 1975-11-10 | 1977-05-16 | Asahi Chem Ind Co Ltd | Preparation of n-substituted uracil compounds |
-
1976
- 1976-11-30 DK DK539376AA patent/DK142415B/da not_active IP Right Cessation
- 1976-12-03 NO NO764136A patent/NO145575C/no unknown
- 1976-12-07 GB GB50989/76A patent/GB1522860A/en not_active Expired
- 1976-12-07 SE SE7613751A patent/SE7613751L/xx not_active Application Discontinuation
- 1976-12-09 CA CA267,561A patent/CA1114376A/en not_active Expired
- 1976-12-10 US US05/749,433 patent/US4256885A/en not_active Expired - Lifetime
- 1976-12-14 DE DE2656604A patent/DE2656604C3/de not_active Expired
- 1976-12-21 NL NL7614220A patent/NL7614220A/xx not_active Application Discontinuation
- 1976-12-21 PH PH19272A patent/PH15812A/en unknown
- 1976-12-21 FI FI763665A patent/FI63758C/fi not_active IP Right Cessation
- 1976-12-23 PT PT66013A patent/PT66013B/pt unknown
- 1976-12-23 FR FR7638941A patent/FR2336401A1/fr active Granted
- 1976-12-23 AT AT961176A patent/AT347477B/de active
- 1976-12-24 CH CH1631676A patent/CH623583A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK142415C (de) | 1981-03-23 |
| PH15812A (en) | 1983-03-25 |
| NO145575B (no) | 1982-01-11 |
| SE7613751L (sv) | 1977-06-25 |
| FR2336401A1 (fr) | 1977-07-22 |
| FI63758C (fi) | 1983-08-10 |
| PT66013A (en) | 1977-01-01 |
| CA1114376A (en) | 1981-12-15 |
| FR2336401B1 (de) | 1980-11-07 |
| DK142415B (da) | 1980-10-27 |
| US4256885A (en) | 1981-03-17 |
| DE2656604C3 (de) | 1980-02-21 |
| CH623583A5 (de) | 1981-06-15 |
| PT66013B (en) | 1978-06-16 |
| DE2656604B2 (de) | 1979-06-21 |
| NO764136L (de) | 1977-06-27 |
| NL7614220A (nl) | 1977-06-28 |
| ATA961176A (de) | 1978-05-15 |
| DK539376A (de) | 1977-06-25 |
| GB1522860A (en) | 1978-08-31 |
| FI763665A (de) | 1977-06-25 |
| NO145575C (no) | 1982-04-21 |
| DE2656604A1 (de) | 1977-07-14 |
| FI63758B (fi) | 1983-04-29 |
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