AT343123B - Verfahren zur herstellung von neuen piperazinderivaten - Google Patents

Verfahren zur herstellung von neuen piperazinderivaten

Info

Publication number
AT343123B
AT343123B AT848675A AT848675A AT343123B AT 343123 B AT343123 B AT 343123B AT 848675 A AT848675 A AT 848675A AT 848675 A AT848675 A AT 848675A AT 343123 B AT343123 B AT 343123B
Authority
AT
Austria
Prior art keywords
production
piperazine derivatives
new piperazine
new
derivatives
Prior art date
Application number
AT848675A
Other languages
English (en)
Other versions
ATA848675A (de
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7436963A external-priority patent/FR2313060A1/fr
Priority claimed from FR7527161A external-priority patent/FR2322601A1/fr
Priority claimed from FR7527162A external-priority patent/FR2322602A1/fr
Priority claimed from FR7527160A external-priority patent/FR2322600A1/fr
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Priority to AT402077A priority Critical patent/AT343667B/de
Publication of ATA848675A publication Critical patent/ATA848675A/de
Application granted granted Critical
Publication of AT343123B publication Critical patent/AT343123B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT848675A 1974-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten AT343123B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT402077A AT343667B (de) 1975-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR7436963A FR2313060A1 (fr) 1974-11-07 1974-11-07 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527161A FR2322601A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'isoindoline, leur preparation et les compositions qui les contiennent
FR7527162A FR2322602A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de l'oxathiinno- et du dithiinnopyrrole, leur preparation et les compositions qui les contiennent
FR7527160A FR2322600A1 (fr) 1975-09-04 1975-09-04 Nouveaux derives de la pyrrolo (3,4-b) pyrazine, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
ATA848675A ATA848675A (de) 1977-09-15
AT343123B true AT343123B (de) 1978-05-10

Family

ID=27446274

Family Applications (2)

Application Number Title Priority Date Filing Date
AT848675A AT343123B (de) 1974-11-07 1975-11-07 Verfahren zur herstellung von neuen piperazinderivaten
AT401977A AT343666B (de) 1974-11-07 1977-06-07 Verfahren zur herstellung von neuen piperazinderivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT401977A AT343666B (de) 1974-11-07 1977-06-07 Verfahren zur herstellung von neuen piperazinderivaten

Country Status (27)

Country Link
US (1) US4220646A (de)
JP (2) JPS5422996B2 (de)
AR (2) AR208414A1 (de)
AT (2) AT343123B (de)
AU (1) AU503200B2 (de)
BE (1) BE835325A (de)
CA (1) CA1057755A (de)
CH (1) CH609057A5 (de)
CS (2) CS231957B2 (de)
CY (1) CY1045A (de)
DD (1) DD122684A5 (de)
DE (1) DE2550111C2 (de)
DK (1) DK141098B (de)
FI (1) FI60707C (de)
GB (1) GB1468497A (de)
HK (1) HK19380A (de)
HU (1) HU173108B (de)
IE (1) IE41928B1 (de)
IL (1) IL48423A (de)
LU (1) LU73738A1 (de)
NL (1) NL177405C (de)
NO (1) NO143576C (de)
OA (1) OA05162A (de)
PL (1) PL101248B1 (de)
SE (1) SE407063B (de)
SU (2) SU673173A3 (de)
YU (2) YU39583B (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2371198A2 (fr) * 1976-11-22 1978-06-16 Rhone Poulenc Ind Nouveaux derives du dithiepinno (1,4)(2,3-c) pyrrole, leur preparation et les compositions qui les contiennent
US4533751A (en) * 1981-10-09 1985-08-06 Scm Corporation Preparation of 1,3-dienamines from myrcene and substituted myrcene
FR2525606A1 (fr) * 1982-04-22 1983-10-28 Rhone Poulenc Sante Nouveaux derives du dithiino (1,4) (2,3-c) pyrrole, leur preparation et les medicaments qui les contiennent
FR2607506B1 (fr) * 1986-12-02 1989-01-06 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2607504B1 (fr) * 1986-12-02 1989-01-27 Rhone Poulenc Sante Nouveaux derives de l'isoindolinone, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2671800B1 (fr) * 1991-01-17 1993-03-12 Rhone Poulenc Rorer Sa Derive de la 5h-pyrrolo[3,4-b]pyrazine optiquement actif, sa preparation et les compositions pharmaceutiques qui le contiennent.
US5786357A (en) 1991-12-02 1998-07-28 Sepracor Inc. Methods and compositions for treating sleep disorders, convulsive seizures and other disorders using optically pure (+) zopiclone
HU214331B (hu) * 1992-06-17 1998-03-02 Gyógyszerkutató Intézet Kft. Eljárás piperazin- és homopiperazinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
JPH08511022A (ja) * 1993-06-04 1996-11-19 ヘンケル コーポレーション 重合可能な化合物
US5922820A (en) * 1993-06-04 1999-07-13 Henkel Corporation Polymerizable compounds
US5565567A (en) * 1993-06-04 1996-10-15 Henkel Corporation. Polymerizable N,N'-substituted piperazine acrylamide compounds
CN1160398A (zh) * 1994-09-23 1997-09-24 阿瑞斯药物公司 治疗肥大细胞炎性疾病的组合物和方法
US5663357A (en) * 1995-11-22 1997-09-02 Allergan Substituted heteroarylamides having retinoid-like biological activity
US5756742A (en) * 1995-12-22 1998-05-26 Henkel Corporation Polymerizable compounds
US6339086B1 (en) * 1999-05-14 2002-01-15 Swpracor, Inc. Methods of making and using N-desmethylzopiclone
JP4196678B2 (ja) * 2001-04-26 2008-12-17 味の素株式会社 複素環化合物
EP1490363B1 (de) * 2002-03-29 2006-01-25 Indevus Pharmaceuticals, Inc. Verfahren zur herstellung von 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxo-hexyl)-1-isoindolinon
AU2003285012A1 (en) * 2002-10-24 2004-05-13 Sepracor, Inc. Compositions comprising zopiclone derivatives and methods of making and using the same
US6909002B2 (en) * 2002-11-22 2005-06-21 Merck & Co., Inc. Method of preparing inhibitors of phosphodiesterase-4
AR042194A1 (es) * 2002-11-22 2005-06-15 Merck & Co Inc Metodo para preparar inhibidores de fosfodiesterasa - 4
CN1326856C (zh) * 2002-11-22 2007-07-18 麦克公司 制备磷酸二酯酶－4抑制剂的方法
PT1691811E (pt) 2003-12-11 2014-10-30 Sunovion Pharmaceuticals Inc Combinação de um sedativo e de um modulador de neurotransmissores e métodos para melhorar a qualidade do sono e tratamento da depressão
US20050232983A1 (en) * 2004-04-14 2005-10-20 Indevus Pharmaceuticals, Inc. Transdermal patch
MX2008000250A (es) 2005-07-06 2008-03-19 Sepracor Inc Combinaciones de eszopiclona y trans-4-(3,4-diclorofenil)-1,2,3,4- tetrahidro-n-metil-1-naftalenamina o trans 4-(3,4-diclorofenil)-1, 2,3,4-tetrahidro-1-naftalenamina y metodos de tratamiento de menopausia y trastornos del estado de animo, ansiedad y
WO2007005961A2 (en) * 2005-07-06 2007-01-11 Sepracor Inc. Combinations of eszopiclone and o-desmethylvenlafaxine, and methods of treatment of menopause and mood, anxiety, and cognitive disorders
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
US7678363B2 (en) 2005-08-26 2010-03-16 Braincells Inc Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2021000A2 (de) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenese mittels angiotensin-modulation
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
EP2068872A1 (de) 2006-09-08 2009-06-17 Braincells, Inc. Kombinationen mit einem 4-acylaminopyridin-derivat
US20080305171A1 (en) * 2007-06-07 2008-12-11 Kristin Anne Arnold Pyrrolopyrazine, formulations, methods of manufacture, and methods of use there
CN100569775C (zh) * 2007-12-19 2009-12-16 齐鲁天和惠世制药有限公司 佐匹克隆的晶型转换的方法
AU2010208240A1 (en) 2009-01-30 2011-09-22 Sunovion Pharmaceuticals Inc Coated tablets of 6-(5-chloro-2-pyridyl) -5-[ (4-methyl-1-piperazinyl) carbonyloxy]-7-oxo-6, 7-dihydro-5H-pyrrol o [3,4-b] pyrazine and methods for measuring effectiveness of coating
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US11820912B2 (en) * 2017-05-25 2023-11-21 Shin-Etsu Chemical Co., Ltd. Fluoropolyether group-containing polymer-modified organic silicon compound, surface treatment agent, and article
CN108129476A (zh) * 2017-11-27 2018-06-08 华中农业大学 一种杂环内酰胺衍生物及其用于作物病原菌杀菌剂的用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1312427A (fr) * 1961-04-12 1962-12-21 Science Union Et Compagnie Soc Nouveaux dérivés de la pipérazine et leurs préparations
FR2101081B1 (de) * 1970-08-19 1974-01-11 Rhone Poulenc Sa
BE790408A (fr) * 1971-10-22 1973-04-20 Rhone Poulenc Sa Nouveaux derives de la pyrrolo (3,4-b) pyridine, leur preparation et les compositions medicinales qui les
OA04285A (fr) * 1972-01-07 1979-12-31 Rhone Poulenc Sa Nouveaux dérivés de la pyrrolo (3,4-b) pyrazine et leur préparation.
BE793851A (fr) * 1972-01-10 1973-07-10 Rhone Poulenc Sa Nouveaux derives de l'isoindoline, leur preparation et les compositions medicinales qui les contiennent
AR207555A1 (es) * 1972-12-04 1976-10-15 Procedimiento para preparar aril-6-piperazinocarboniloxi-5 oxo-7 tetrahidro-2,3,6,7 ditiino(1,4)(2,3-c)pirroles
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.

Also Published As

Publication number Publication date
NO143576B (no) 1980-12-01
BE835325A (fr) 1976-05-06
DD122684A5 (de) 1976-10-20
SE7512477L (sv) 1976-05-08
AT343666B (de) 1978-06-12
DK499275A (de) 1976-05-08
AR208800A1 (es) 1977-02-28
HK19380A (en) 1980-04-18
YU281575A (en) 1983-01-21
IE41928B1 (en) 1980-04-23
ATA401977A (de) 1977-10-15
AU503200B2 (en) 1979-08-30
NL7512732A (nl) 1976-05-11
SE407063B (sv) 1979-03-12
CS751075A2 (en) 1984-01-16
IL48423A (en) 1979-03-12
JPS5498790A (en) 1979-08-03
JPS5170776A (de) 1976-06-18
OA05162A (fr) 1981-01-31
US4220646A (en) 1980-09-02
FI753127A (de) 1976-05-08
HU173108B (hu) 1979-02-28
GB1468497A (en) 1977-03-30
JPS5422996B2 (de) 1979-08-10
JPS558508B2 (de) 1980-03-04
YU39583B (en) 1985-03-20
NO753713L (de) 1976-05-10
FI60707C (fi) 1982-03-10
AU8633175A (en) 1977-05-12
DE2550111A1 (de) 1976-05-13
ATA848675A (de) 1977-09-15
NL177405B (nl) 1985-04-16
DK141098B (da) 1980-01-14
IL48423A0 (en) 1976-01-30
CA1057755A (fr) 1979-07-03
PL101248B1 (pl) 1978-12-30
CS231958B2 (en) 1985-01-16
NO143576C (no) 1981-03-11
CS231957B2 (en) 1985-01-16
DK141098C (de) 1980-07-07
IE41928L (en) 1976-05-07
CS598377A2 (en) 1984-01-16
AR208414A1 (es) 1976-12-27
DE2550111C2 (de) 1983-09-15
CY1045A (en) 1980-08-01
SU673173A3 (ru) 1979-07-05
LU73738A1 (de) 1976-09-06
NL177405C (nl) 1985-09-16
CH609057A5 (de) 1979-02-15
FI60707B (fi) 1981-11-30
SU604496A3 (ru) 1978-04-25
YU40087B (en) 1985-06-30
YU192182A (en) 1983-01-21

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