AT341665B - Verfahren zur herstellung von neuen r-sulfoxyden von 7-amino-cephalosporansauren - Google Patents

Verfahren zur herstellung von neuen r-sulfoxyden von 7-amino-cephalosporansauren

Info

Publication number
AT341665B
AT341665B AT626873A AT626873A AT341665B AT 341665 B AT341665 B AT 341665B AT 626873 A AT626873 A AT 626873A AT 626873 A AT626873 A AT 626873A AT 341665 B AT341665 B AT 341665B
Authority
AT
Austria
Prior art keywords
sulfoxyde
amino
preparation
new
cephalosporanic acids
Prior art date
Application number
AT626873A
Other languages
English (en)
Other versions
ATA626873A (de
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Publication of ATA626873A publication Critical patent/ATA626873A/de
Application granted granted Critical
Publication of AT341665B publication Critical patent/AT341665B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04Preparation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
AT626873A 1972-07-18 1973-07-17 Verfahren zur herstellung von neuen r-sulfoxyden von 7-amino-cephalosporansauren AT341665B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3359672A GB1442993A (en) 1972-07-18 1972-07-18 Penicillin and cephalosporin r-sulphoxides
GB4872072 1972-10-23

Publications (2)

Publication Number Publication Date
ATA626873A ATA626873A (de) 1977-06-15
AT341665B true AT341665B (de) 1978-02-27

Family

ID=26261933

Family Applications (1)

Application Number Title Priority Date Filing Date
AT626873A AT341665B (de) 1972-07-18 1973-07-17 Verfahren zur herstellung von neuen r-sulfoxyden von 7-amino-cephalosporansauren

Country Status (7)

Country Link
JP (1) JPS4980089A (de)
AT (1) AT341665B (de)
DE (1) DE2336344A1 (de)
FR (1) FR2192805B1 (de)
GB (1) GB1442993A (de)
HU (1) HU170698B (de)
NL (1) NL7309918A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6019316B2 (ja) * 1976-01-29 1985-05-15 塩野義製薬株式会社 ペニシリンオキシド
DE2716677C2 (de) 1977-04-15 1985-10-10 Hoechst Ag, 6230 Frankfurt Cephemderivate und Verfahren zu ihrer Herstellung
US4230620A (en) * 1979-03-26 1980-10-28 Eli Lilly And Company Process for preparing penicillin sulfoxides
JPS58986A (ja) * 1981-05-07 1983-01-06 Fujisawa Pharmaceut Co Ltd セフェム化合物
CA2067745A1 (en) * 1989-10-16 1991-04-17 Paulus Gerhardus Johannes Nieuwenhuis Conversion of penicillins and cephalosporins to 1-(s)-sulfoxides

Also Published As

Publication number Publication date
FR2192805B1 (de) 1976-09-03
NL7309918A (de) 1974-01-22
FR2192805A1 (de) 1974-02-15
GB1442993A (en) 1976-07-21
DE2336344A1 (de) 1974-03-14
HU170698B (de) 1977-08-28
JPS4980089A (de) 1974-08-02
ATA626873A (de) 1977-06-15

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Legal Events

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ELJ Ceased due to non-payment of the annual fee