AT334373B - PROCESS FOR THE PREPARATION OF NEW 4-HYDROXY-3-NITROCARBOSTYRIL DERIVATIVES AND THEIR SALTS - Google Patents

PROCESS FOR THE PREPARATION OF NEW 4-HYDROXY-3-NITROCARBOSTYRIL DERIVATIVES AND THEIR SALTS

Info

Publication number
AT334373B
AT334373B AT409674A AT409674A AT334373B AT 334373 B AT334373 B AT 334373B AT 409674 A AT409674 A AT 409674A AT 409674 A AT409674 A AT 409674A AT 334373 B AT334373 B AT 334373B
Authority
AT
Austria
Prior art keywords
nitrocarbostyril
hydroxy
derivatives
salts
preparation
Prior art date
Application number
AT409674A
Other languages
German (de)
Other versions
ATA409674A (en
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Application granted granted Critical
Publication of AT334373B publication Critical patent/AT334373B/en
Publication of ATA409674A publication Critical patent/ATA409674A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/10—Aza-phenanthrenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT409674A 1973-05-19 1974-05-17 PROCESS FOR THE PREPARATION OF NEW 4-HYDROXY-3-NITROCARBOSTYRIL DERIVATIVES AND THEIR SALTS AT334373B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2400073A GB1453863A (en) 1973-05-19 1973-05-19 Pharmaceutical compositions comprising nitrocarbostyrils for the treatment of allergic and immunological hypersensitivity
GB2431773 1973-05-22

Publications (2)

Publication Number Publication Date
AT334373B true AT334373B (en) 1976-01-10
ATA409674A ATA409674A (en) 1976-05-15

Family

ID=26256830

Family Applications (1)

Application Number Title Priority Date Filing Date
AT409674A AT334373B (en) 1973-05-19 1974-05-17 PROCESS FOR THE PREPARATION OF NEW 4-HYDROXY-3-NITROCARBOSTYRIL DERIVATIVES AND THEIR SALTS

Country Status (21)

Country Link
JP (1) JPS5030884A (en)
AR (1) AR201506A1 (en)
AT (1) AT334373B (en)
CA (1) CA1030539A (en)
CH (1) CH601243A5 (en)
DD (1) DD112126A5 (en)
DE (1) DE2424076A1 (en)
DK (1) DK137043B (en)
ES (1) ES426427A1 (en)
FI (1) FI153174A (en)
FR (1) FR2229414B1 (en)
GB (1) GB1453863A (en)
HU (1) HU168001B (en)
IE (1) IE39269B1 (en)
IL (1) IL44849A (en)
IN (1) IN139603B (en)
NL (1) NL7406711A (en)
PH (1) PH10621A (en)
SE (1) SE7406631L (en)
SU (1) SU578869A3 (en)
ZM (1) ZM7974A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4065457A (en) * 1973-05-19 1977-12-27 Beecham Group Limited 4-Hydroxy-3-nitro-carbostyril compounds
US4192876A (en) * 1975-07-23 1980-03-11 Sandoz, Inc. 4-Hydroxy-3-nitro-quinoline-2(1H)-ones
DE2631317A1 (en) * 1975-07-23 1977-02-17 Sandoz Ag ORGANIC COMPOUNDS, THEIR USE AND MANUFACTURING
JPS5919095B2 (en) * 1977-06-22 1984-05-02 大塚製薬株式会社 Quinoline derivatives and their production method
JPH0681744B2 (en) * 1986-10-06 1994-10-19 三菱化成株式会社 Method for producing 2,4-dioxyquinoline derivative
US5622965A (en) * 1993-03-12 1997-04-22 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon 4-hydroxy-3-nitro-1,2-dihydroquinolin-2-ones and the use thereof as excitatory amino acid and glycine receptor antagonists

Also Published As

Publication number Publication date
ES426427A1 (en) 1976-09-16
IE39269B1 (en) 1978-08-30
ATA409674A (en) 1976-05-15
CH601243A5 (en) 1978-06-30
CA1030539A (en) 1978-05-02
DK137043B (en) 1978-01-09
SE7406631L (en) 1974-11-20
HU168001B (en) 1976-02-28
IE39269L (en) 1974-11-19
IL44849A0 (en) 1974-07-31
AR201506A1 (en) 1975-03-21
NL7406711A (en) 1974-11-21
AU6915874A (en) 1975-11-20
FR2229414B1 (en) 1977-11-10
DD112126A5 (en) 1975-03-20
IL44849A (en) 1978-04-30
FR2229414A1 (en) 1974-12-13
ZM7974A1 (en) 1974-12-20
GB1453863A (en) 1976-10-27
FI153174A (en) 1974-11-20
SU578869A3 (en) 1977-10-30
DE2424076A1 (en) 1974-12-05
IN139603B (en) 1976-07-10
DK137043C (en) 1978-06-05
PH10621A (en) 1977-07-19
JPS5030884A (en) 1975-03-27

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee