AT328447B - Verfahren zur herstellung neuer 1,4-dihydropyridine - Google Patents

Verfahren zur herstellung neuer 1,4-dihydropyridine

Info

Publication number: AT328447B
Authority: AT; Austria
Prior art keywords: dihydropyridine; preparing new; preparing; new
Prior art date: 1972-06-10

Application number

AT507473A

Other languages

English (en)

Other versions

ATA507473A (de

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-10

Filing date

1973-06-08

Publication date

1976-03-25

1973-06-08 Application filed by Bayer Ag filed Critical Bayer Ag

1975-03-07 Priority to AT177175A priority Critical patent/AT332405B/de

1975-06-15 Publication of ATA507473A publication Critical patent/ATA507473A/de

1976-03-25 Application granted granted Critical

1976-03-25 Publication of AT328447B publication Critical patent/AT328447B/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)

AT507473A 1972-06-10 1973-06-08 Verfahren zur herstellung neuer 1,4-dihydropyridine AT328447B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT177175A AT332405B (de)	1972-06-10	1975-03-07	Verfahren zur herstellung neuer 1,4-dihydropyridine

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE2228363A DE2228363A1 (de)	1972-06-10	1972-06-10	1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (2)

Publication Number	Publication Date
ATA507473A ATA507473A (de)	1975-06-15
AT328447B true AT328447B (de)	1976-03-25

Family

ID=5847399

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT177075*7A AT329561B (de)	1972-06-10	1973-06-08	Verfahren zur herstellung neuer 1,4-dihydropyridine
AT507473A AT328447B (de)	1972-06-10	1973-06-08	Verfahren zur herstellung neuer 1,4-dihydropyridine

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT177075*7A AT329561B (de)	1972-06-10	1973-06-08	Verfahren zur herstellung neuer 1,4-dihydropyridine

Country Status (19)

Country	Link
US (1)	US3923818A (de)
JP (1)	JPS4948680A (de)
AT (2)	AT329561B (de)
AU (1)	AU473996B2 (de)
BE (1)	BE800679A (de)
CA (1)	CA999592A (de)
CH (7)	CH589058A5 (de)
CS (5)	CS178900B2 (de)
DD (1)	DD109383A5 (de)
DE (1)	DE2228363A1 (de)
ES (5)	ES415749A1 (de)
FR (1)	FR2187347B1 (de)
GB (1)	GB1425059A (de)
HU (1)	HU166354B (de)
IE (1)	IE37773B1 (de)
IL (1)	IL42458A (de)
NL (1)	NL7308059A (de)
SU (5)	SU511856A3 (de)
ZA (1)	ZA733880B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3981882A (en) *	1972-08-31	1976-09-21	Bayer Aktiengesellschaft	Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester
US3971796A (en) *	1973-07-12	1976-07-27	Bayer Aktiengesellschaft	1,4-Dihydropyridine esters
US4466972A (en) *	1977-06-20	1984-08-21	Sandoz Ltd.	Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
DE2847236A1 (de) *	1978-10-31	1980-05-14	Bayer Ag	Neue dihydropyridine mit substituierten estergruppierungen, mehrer verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4252956A (en) *	1979-03-19	1981-02-24	Vigante Brigita A	Derivatives of 1,4-dihydropyridine-3-carbothiol acids
GB2111978B (en) *	1981-10-19	1985-05-01	Maruko Pharmaceutical Co	1 4-dihydropyridine compounds
DE3207982A1 (de) *	1982-03-05	1983-09-08	Bayer Ag, 5090 Leverkusen	Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
IE57810B1 (en) *	1984-03-27	1993-04-21	Delagrange Lab	1,4-dihydropyridine derivatives,their preparation and their use
NZ212895A (en) *	1984-08-22	1988-07-28	Glaxo Spa	1,4-dihydropyridine derivatives and pharmaceutical compositions
JPS60210640A (ja) *	1984-10-05	1985-10-23	Hitachi Chem Co Ltd	積層板の製造法
GB8503425D0 (en) *	1985-02-11	1985-03-13	Ici Plc	Alkanolamine derivatives
GB8503427D0 (en) *	1985-02-11	1985-03-13	Ici Plc	Basic compounds
GB8503428D0 (en) *	1985-02-11	1985-03-13	Ici Plc	Nitrogen-containing compounds
GB8503429D0 (en) *	1985-02-11	1985-03-13	Ici Plc	Chemical compounds
US4593033A (en) *	1985-04-24	1986-06-03	Merck & Co., Inc.	Substituted indeno[2,1-c] pyridines useful as calcium channel blockers
US4605660A (en) *	1985-06-03	1986-08-12	Merck & Co., Inc.	Indeno[2,1-c]pyridine compounds, and their use as calcium channel blockers
US4670443A (en) *	1985-07-02	1987-06-02	Merck & Co., Inc.	Benzo(f)isoquinoline compounds useful as calcium entry blockers
EP0226271B1 (de) *	1985-08-21	1990-11-22	GLAXO S.p.A.	1,4-Dihydropyridinverbindungen und ihre Herstellung und pharmazeutische Formulierung
ES2001104A6 (es) *	1985-08-21	1988-04-16	Glaxo Spa	Un procedimiento para la preparacion de nuevos derivados sustituidos del acido 1,4-dihidro-3,5-piridindicarboxilico.
US4735956A (en) *	1985-09-13	1988-04-05	Merck & Co., Inc.	Certain 1,4-dihydro-2,6-di-lower hydrocarbyl-4-heterocyclic-3,5-pyridine dicarboxylates which are useful as calcium channel blockers
US4788203A (en) *	1985-11-26	1988-11-29	Merck & Co., Inc.	Cyclized N-substituted-tetrahydropyridine compounds, useful in the treatment of cardiovascular disorders
US4721708A (en) *	1985-11-26	1988-01-26	Merck & Co., Inc.	Cyclized N-substituted-tetrahydropyridine compounds and cardiovascular use
IT1204460B (it) *	1986-02-20	1989-03-01	Glaxo Spa	Derivati eterociclici
IT1204462B (it) *	1986-02-20	1989-03-01	Glaxo Spa	Derivati eterociclici
EP0330470A3 (de) *	1988-02-24	1992-01-02	Ajinomoto Co., Inc.	Gegen Tumorzellen verwendbare 1,4-Dihydropyridin-Derivate
US5216172A (en) *	1988-02-24	1993-06-01	Ajinomoto Co., Inc.	1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
FR2672890A1 (fr) *	1991-02-20	1992-08-21	Inst Investigacion Desarrol	Derives de 2,6-dimethyl-4-(4'-hydroxy-3',5'-di-t-butylphenyl)-1,4-dihydropyridine, leur procede de preparation et leur utilisation comme capteurs de radicaux libres.
EP1108710A4 (de) *	1998-07-23	2001-11-21	Chen Ing Jun	Guaiacoxypropanolamine mit alpha/beta-adrenerger hemmaktivität
US20030129186A1 (en)	2001-07-25	2003-07-10	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
US20030153773A1 (en) *	2002-02-14	2003-08-14	Wayne Gregory S.	Process for the production of dihydropyridines
WO2005016885A2 (en) *	2003-08-14	2005-02-24	Artesian Therapeutics, Inc.	COMPOUNDS WITH COMBINED CALCIUM CHANNEL BLOCKER AND β-ADRENERGIC ANTAGONIST OR PARTIAL AGONIST ACTIVITIES FOR TREATMENT OF HEART DISEASE
SI1889198T1 (sl)	2005-04-28	2015-02-27	Proteus Digital Health, Inc.	Farma-informacijski sistem
EP2063905B1 (de)	2006-09-18	2014-07-30	Raptor Pharmaceutical Inc	Behandlungen von lebererkrankungen durch verabreichung von konjugaten aus rezeptor-assoziierten proteinen
DK2398500T3 (da)	2009-02-20	2019-05-13	2 Bbb Medicines B V	Glutathion-baseret lægemiddelafgivelsessystem
ES2942923T3 (es)	2009-05-06	2023-06-07	Laboratory Skin Care Inc	Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1923990C3 (de) *	1969-05-10	1978-11-23	Bayer Ag	Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern
ZA7152B (en) *	1970-01-24	1971-10-27	Bayer Ag	New pharmaceutically active 1,4-dihydropyridines

1972
- 1972-06-10 DE DE2228363A patent/DE2228363A1/de active Pending
1973
- 1973-05-31 SU SU1926944A patent/SU511856A3/ru active
- 1973-06-04 US US366578A patent/US3923818A/en not_active Expired - Lifetime
- 1973-06-07 JP JP48063442A patent/JPS4948680A/ja active Pending
- 1973-06-07 CA CA173,419A patent/CA999592A/en not_active Expired
- 1973-06-07 IL IL7342458A patent/IL42458A/en unknown
- 1973-06-07 HU HUBA2938A patent/HU166354B/hu unknown
- 1973-06-08 BE BE132064A patent/BE800679A/xx unknown
- 1973-06-08 CH CH250477A patent/CH589058A5/xx not_active IP Right Cessation
- 1973-06-08 CH CH250377A patent/CH591444A5/xx not_active IP Right Cessation
- 1973-06-08 DD DD171438A patent/DD109383A5/xx unknown
- 1973-06-08 NL NL7308059A patent/NL7308059A/xx not_active Application Discontinuation
- 1973-06-08 CH CH725776A patent/CH593260A5/xx not_active IP Right Cessation
- 1973-06-08 ZA ZA733880A patent/ZA733880B/xx unknown
- 1973-06-08 AU AU56725/73A patent/AU473996B2/en not_active Expired
- 1973-06-08 CS CS7600001305A patent/CS178900B2/cs unknown
- 1973-06-08 FR FR7320978A patent/FR2187347B1/fr not_active Expired
- 1973-06-08 IE IE932/73A patent/IE37773B1/xx unknown
- 1973-06-08 AT AT177075*7A patent/AT329561B/de not_active IP Right Cessation
- 1973-06-08 CS CS7600001303A patent/CS178898B2/cs unknown
- 1973-06-08 CH CH725676A patent/CH588462A5/xx not_active IP Right Cessation
- 1973-06-08 CS CS7600001304A patent/CS178899B2/cs unknown
- 1973-06-08 CS CS7300004161A patent/CS178888B2/cs unknown
- 1973-06-08 CH CH836973A patent/CH591443A5/xx not_active IP Right Cessation
- 1973-06-08 CH CH725876A patent/CH589628A5/xx not_active IP Right Cessation
- 1973-06-08 GB GB2746373A patent/GB1425059A/en not_active Expired
- 1973-06-08 CS CS7600001302A patent/CS178897B2/cs unknown
- 1973-06-08 CH CH725976A patent/CH589629A5/xx not_active IP Right Cessation
- 1973-06-08 AT AT507473A patent/AT328447B/de not_active IP Right Cessation
- 1973-06-09 ES ES415749A patent/ES415749A1/es not_active Expired
1974
- 1974-06-27 SU SU2038430A patent/SU510997A3/ru active
- 1974-06-27 SU SU2038435A patent/SU507234A3/ru active
- 1974-07-23 SU SU2050563A patent/SU509221A3/ru active
- 1974-07-23 SU SU2050564A patent/SU512708A3/ru active
1975
- 1975-09-01 ES ES440622A patent/ES440622A1/es not_active Expired
- 1975-09-01 ES ES440621A patent/ES440621A1/es not_active Expired
- 1975-09-01 ES ES440619A patent/ES440619A1/es not_active Expired
- 1975-09-01 ES ES440620A patent/ES440620A1/es not_active Expired

Also Published As

Publication number	Publication date
SU511856A3 (ru)	1976-04-25
IL42458A0 (en)	1973-08-29
DD109383A5 (de)	1974-11-05
NL7308059A (de)	1973-12-12
ES415749A1 (es)	1976-06-16
IE37773L (en)	1973-12-10
DE2228363A1 (de)	1974-01-03
AT329561B (de)	1976-05-25
IE37773B1 (en)	1977-10-12
CS178888B2 (en)	1977-10-31
GB1425059A (en)	1976-02-18
ATA177075A (de)	1975-08-15
ZA733880B (en)	1974-05-29
SU510997A3 (ru)	1976-04-15
CH591443A5 (de)	1977-09-15
ES440622A1 (es)	1977-03-01
CA999592A (en)	1976-11-09
CS178897B2 (en)	1977-10-31
CH591444A5 (de)	1977-09-15
AU473996B2 (en)	1976-07-08
FR2187347A1 (de)	1974-01-18
ES440619A1 (es)	1977-03-01
JPS4948680A (de)	1974-05-11
AU5672573A (en)	1974-12-12
IL42458A (en)	1977-07-31
HU166354B (de)	1975-03-28
US3923818A (en)	1975-12-02
ES440621A1 (es)	1977-03-01
CH588462A5 (de)	1977-06-15
BE800679A (fr)	1973-12-10
CS178898B2 (en)	1977-10-31
CS178900B2 (en)	1977-10-31
SU512708A3 (ru)	1976-04-30
CH589629A5 (de)	1977-07-15
SU509221A3 (ru)	1976-03-30
ES440620A1 (es)	1977-03-01
CS178899B2 (en)	1977-10-31
SU507234A3 (ru)	1976-03-15
CH589628A5 (de)	1977-07-15
ATA507473A (de)	1975-06-15
CH593260A5 (de)	1977-11-30
FR2187347B1 (de)	1977-09-09
CH589058A5 (de)	1977-06-30

Legal Events

Date	Code	Title	Description
1981-03-15	ELJ	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
AT329561B (de)	1976-05-25	Verfahren zur herstellung neuer 1,4-dihydropyridine
DD110652A5 (de)	1975-01-05	Verfahren zur herstellung neuer 1-aryloxy-2-hydroxy-3-alkinylaminopropane
ATA588973A (de)	1976-08-15	Verfahren zur herstellung neuer phenoxypropanolamine
CH549600A (de)	1974-05-31	Verfahren zur herstellung neuer n (6)-aralkyl-adenosinderivate.
AT324310B (de)	1975-08-25	Verfahren zur herstellung neuer 2-aminoalkanoylaminobenzophenone
CH555798A (de)	1974-11-15	Verfahren zur herstellung neuer 1,1-diphenyl-2-nitropropanderivate.
AT329570B (de)	1976-05-25	Verfahren zur herstellung neuer chinazolinonderivate
AT331255B (de)	1976-08-10	Verfahren zur herstellung neuer hexahydrotriazinonderivate
AT327414B (de)	1976-01-26	Verfahren zur herstellung neuer bis-piperazino-androstan-derivate
AT326653B (de)	1975-12-29	Verfahren zur herstellung neuer 2-amino-4-h-pyrane
AT327881B (de)	1976-02-25	Verfahren zur herstellung neuer furanderivate
AT367067B (de)	1982-05-25	Verfahren zur herstellung neuer 11,11-alkyliden- steroide
ATA470873A (de)	1979-11-15	Verfahren zur herstellung neuer anhydro- furanosederivate
ATA177175A (de)	1976-01-15	Verfahren zur herstellung neuer 1,4-dihydropyridine
AT326120B (de)	1975-11-25	Verfahren zur herstellung neuer isoxazolidinderivate
ATA173876A (de)	1979-12-15	Verfahren zur herstellung neuer 2,3-dihydro- benzofuranon-2-derivate
AT327192B (de)	1976-01-26	Verfahren zur herstellung neuer 1-(dialkylphenyl-phenyl-pyridyl)-methyl-imidazole
AT323893B (de)	1975-08-11	Verfahren zur herstellung von 8-oxo-5-thia-1-azabicyclo (4,2,0) oct-2-en-verbindungen
AT340396B (de)	1977-12-12	Verfahren zur herstellung neuer substituierter chloracetanilide
AT331203B (de)	1976-08-10	Verfahren zur herstellung von 1,2-dichlorathan
AT335462B (de)	1977-03-10	Verfahren zur herstellung neuer 1-nitrosoharnstoffderivate
AT322542B (de)	1975-05-26	Verfahren zur herstellung neuer nitrofuranverbindungen
AT332386B (de)	1976-09-27	Verfahren zur herstellung neuer 2-(-phenyl-n-(r1, r2-aminoalkyl- oder -alkanoyl))-amino-(1,2,3,4,-tetrahydronaphthalin)
AT332417B (de)	1976-09-27	Verfahren zur herstellung neuer 1,2,4- benztriazin -1,4-di-n- oxidderivate
ATA217775A (de)	1978-07-15	Verfahren zur herstellung neuer phenoxypropanolamine