AT253687B - Process for the production of new benzomorphans - Google Patents
Process for the production of new benzomorphansInfo
- Publication number
- AT253687B AT253687B AT1074364A AT1074364A AT253687B AT 253687 B AT253687 B AT 253687B AT 1074364 A AT1074364 A AT 1074364A AT 1074364 A AT1074364 A AT 1074364A AT 253687 B AT253687 B AT 253687B
- Authority
- AT
- Austria
- Prior art keywords
- benzomorphans
- new
- production
- new benzomorphans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/82—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Discharge Lamp (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33229663A | 1963-12-20 | 1963-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT253687B true AT253687B (en) | 1967-04-25 |
Family
ID=23297612
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT392965A AT249277B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
| AT392865A AT249276B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
| AT1074264A AT261126B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
| AT1074364A AT253687B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT392965A AT249277B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
| AT392865A AT249276B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
| AT1074264A AT261126B (en) | 1963-12-20 | 1964-12-18 | Process for the production of new benzomorphans |
Country Status (12)
| Country | Link |
|---|---|
| AT (4) | AT249277B (en) |
| BE (2) | BE657405A (en) |
| CH (7) | CH448118A (en) |
| DE (2) | DE1445853A1 (en) |
| DK (4) | DK108495C (en) |
| ES (4) | ES307302A1 (en) |
| FR (2) | FR4345M (en) |
| GB (2) | GB1077711A (en) |
| IL (2) | IL22643A (en) |
| NL (3) | NL6414821A (en) |
| NO (2) | NO119273B (en) |
| SE (2) | SE322779B (en) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923454B2 (en) | 2002-05-17 | 2011-04-12 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| US7501433B2 (en) | 2002-05-17 | 2009-03-10 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP1506174B1 (en) | 2002-05-17 | 2015-09-30 | Taiwanj Pharmaceuticals Co., Ltd. | Use of naltrexone for treating kidney and liver damage |
| US8017622B2 (en) | 2003-05-16 | 2011-09-13 | Jenken Biosciences, Inc. | Opioid and opioid-like compounds and uses thereof |
| EP2125750B1 (en) | 2007-02-26 | 2014-05-21 | Vitae Pharmaceuticals, Inc. | Cyclic urea and carbamate inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| CL2008002199A1 (en) | 2007-07-26 | 2009-10-23 | Vitae Pharmaceuticals Inc | Compounds derived from 1,3-oxazin-2-one; pharmaceutical composition comprising said compounds; and use to treat a disease associated with the activity of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-hsd1) such as dyslipidemia, hyperlipidemia, hypertension, obesity and cardiovascular disease, among others. |
| AR069207A1 (en) | 2007-11-07 | 2010-01-06 | Vitae Pharmaceuticals Inc | CYCLIC UREAS AS INHIBITORS OF THE 11 BETA - HIDROXI-ESTEROIDE DESHIDROGENASA 1 |
| CL2008003407A1 (en) | 2007-11-16 | 2010-01-11 | Boehringer Ingelheim Int | Substituted heterobicyclo aryl- and heteroarylcarbonyl derivative compounds; pharmaceutical composition; preparation procedure; and its use in the treatment and / or prevention of metabolic disorders, mediated by the inhibition of the enzyme hsd-1. |
| US8440658B2 (en) | 2007-12-11 | 2013-05-14 | Vitae Pharmaceuticals, Inc. | Cyclic urea inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| TW200934490A (en) | 2008-01-07 | 2009-08-16 | Vitae Pharmaceuticals Inc | Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1 |
| US8592409B2 (en) | 2008-01-24 | 2013-11-26 | Vitae Pharmaceuticals, Inc. | Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| JP5734666B2 (en) | 2008-02-11 | 2015-06-17 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | 1,3-oxaazepan-2-one and 1,3-diazepan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase 1 |
| US20110028445A1 (en) * | 2008-02-12 | 2011-02-03 | Boehringer Ingelheim International Gmbh | Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use |
| US8598160B2 (en) | 2008-02-15 | 2013-12-03 | Vitae Pharmaceuticals, Inc. | Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
| JP5538365B2 (en) | 2008-05-01 | 2014-07-02 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Cyclic inhibitor of 11β-hydroxysteroid dehydrogenase 1 |
| US8138178B2 (en) | 2008-05-01 | 2012-03-20 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2009134384A1 (en) | 2008-05-01 | 2009-11-05 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| TW201004945A (en) | 2008-05-01 | 2010-02-01 | Vitae Pharmaceuticals Inc | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| US8765780B2 (en) | 2008-05-13 | 2014-07-01 | Boehringer Ingelheim International Gmbh | Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use |
| WO2010010157A2 (en) | 2008-07-25 | 2010-01-28 | Boehringer Ingelheim International Gmbh | INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1 |
| CN102119160B (en) | 2008-07-25 | 2014-11-05 | 贝林格尔·英格海姆国际有限公司 | Cyclic inhibitors of 11 beta-hydroxysteroid dehydrogenase 1 |
| EP2350068B1 (en) | 2008-10-23 | 2017-08-30 | Boehringer Ingelheim International GmbH | Urea derivatives of substituted nortropanes, medicaments containing such compounds and their use |
| WO2010089303A1 (en) | 2009-02-04 | 2010-08-12 | Boehringer Ingelheim International Gmbh | CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1 |
| MA33216B1 (en) | 2009-04-30 | 2012-04-02 | Boehringer Ingelheim Int | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 |
| EP2438049B1 (en) | 2009-06-02 | 2014-05-14 | Boehringer Ingelheim International GmbH | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| WO2011011123A1 (en) | 2009-06-11 | 2011-01-27 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure |
| EP2448928B1 (en) | 2009-07-01 | 2014-08-13 | Vitae Pharmaceuticals, Inc. | Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 |
| UY33001A (en) | 2009-11-06 | 2011-05-31 | Boehringer Ingelheim Int | ARYL AND HETEROARILCARBONYL HIVAHYDROINDENOPIRIDINE AND OCTAHYDROBENZOQUINOLINE DERIVATIVES |
| JP5860042B2 (en) | 2010-06-16 | 2016-02-16 | ヴァイティー ファーマシューティカルズ，インコーポレイテッド | Substituted 5, 6 and 7 membered heterocycles, medicaments containing such compounds and their use |
| EP2585444B1 (en) | 2010-06-25 | 2014-10-22 | Boehringer Ingelheim International GmbH | Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders |
| JP2013540801A (en) | 2010-11-02 | 2013-11-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Combination medicine for the treatment of metabolic disorders |
| TWI537258B (en) | 2010-11-05 | 2016-06-11 | 百靈佳殷格翰國際股份有限公司 | Aryl-and heteroarylcarbonyl derivatives of hexahydroindenopyridine and octahydrobenzoquinoline |
| US8735585B2 (en) | 2011-08-17 | 2014-05-27 | Boehringer Ingelheim International Gmbh | Indenopyridine derivatives |
-
0
- NL NL127995D patent/NL127995C/xx active
-
1964
- 1964-11-30 CH CH1538364A patent/CH448118A/en unknown
- 1964-11-30 CH CH1538464A patent/CH446371A/en unknown
- 1964-11-30 CH CH1618867A patent/CH449640A/en unknown
- 1964-11-30 CH CH1618967A patent/CH449641A/en unknown
- 1964-11-30 CH CH1619167A patent/CH449643A/en unknown
- 1964-11-30 CH CH1619067A patent/CH449642A/en unknown
- 1964-11-30 CH CH1618767A patent/CH449639A/en unknown
- 1964-12-18 AT AT392965A patent/AT249277B/en active
- 1964-12-18 IL IL2264364A patent/IL22643A/en unknown
- 1964-12-18 SE SE1536064A patent/SE322779B/xx unknown
- 1964-12-18 IL IL2264264A patent/IL22642A/en unknown
- 1964-12-18 DE DE19641445853 patent/DE1445853A1/en active Pending
- 1964-12-18 NL NL6414821A patent/NL6414821A/xx unknown
- 1964-12-18 GB GB5149864A patent/GB1077711A/en not_active Expired
- 1964-12-18 DE DE19641445854 patent/DE1445854A1/en active Pending
- 1964-12-18 AT AT392865A patent/AT249276B/en active
- 1964-12-18 GB GB5150064A patent/GB1092394A/en not_active Expired
- 1964-12-18 SE SE1536164A patent/SE305657B/xx unknown
- 1964-12-18 AT AT1074264A patent/AT261126B/en active
- 1964-12-18 AT AT1074364A patent/AT253687B/en active
- 1964-12-18 NL NL6414820A patent/NL6414820A/xx unknown
- 1964-12-19 ES ES0307302A patent/ES307302A1/en not_active Expired
- 1964-12-19 ES ES0307301A patent/ES307301A1/en not_active Expired
- 1964-12-19 NO NO15606264A patent/NO119273B/no unknown
- 1964-12-19 DK DK626764A patent/DK108495C/en active
- 1964-12-19 ES ES0307300A patent/ES307300A1/en not_active Expired
- 1964-12-19 DK DK626864A patent/DK106552C/en active
- 1964-12-19 DK DK429865A patent/DK108497C/en active
- 1964-12-19 NO NO15606364A patent/NO119274B/no unknown
- 1964-12-19 ES ES0307299A patent/ES307299A1/en not_active Expired
- 1964-12-19 DK DK429765A patent/DK108496C/en active
- 1964-12-21 BE BE657405D patent/BE657405A/xx unknown
- 1964-12-21 BE BE657406D patent/BE657406A/xx unknown
-
1965
- 1965-03-19 FR FR9865A patent/FR4345M/fr active Active
- 1965-03-19 FR FR9866A patent/FR4346M/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| NL127995C (en) | |
| IL22642A (en) | 1968-07-25 |
| CH449642A (en) | 1968-01-15 |
| CH449639A (en) | 1968-01-15 |
| CH449643A (en) | 1968-01-15 |
| NO119273B (en) | 1970-04-27 |
| BE657406A (en) | 1965-06-21 |
| GB1092394A (en) | 1967-11-22 |
| NO119274B (en) | 1970-04-27 |
| DK106552C (en) | 1967-02-20 |
| FR4345M (en) | 1966-08-16 |
| SE322779B (en) | 1970-04-20 |
| IL22643A (en) | 1968-07-25 |
| ES307299A1 (en) | 1965-05-16 |
| ES307302A1 (en) | 1965-05-16 |
| DK108497C (en) | 1967-12-27 |
| AT249277B (en) | 1966-09-12 |
| DK108495C (en) | 1967-12-27 |
| DE1445853A1 (en) | 1968-12-05 |
| GB1077711A (en) | 1967-08-02 |
| AT249276B (en) | 1966-09-12 |
| AT261126B (en) | 1968-04-10 |
| ES307300A1 (en) | 1965-05-01 |
| NL6414821A (en) | 1965-06-21 |
| CH449640A (en) | 1968-01-15 |
| CH448118A (en) | 1967-12-15 |
| DK108496C (en) | 1967-12-27 |
| NL6414820A (en) | 1965-06-21 |
| ES307301A1 (en) | 1965-05-16 |
| FR4346M (en) | 1966-08-16 |
| CH449641A (en) | 1968-01-15 |
| CH446371A (en) | 1967-11-15 |
| DE1445854A1 (en) | 1968-12-05 |
| SE305657B (en) | 1968-11-04 |
| BE657405A (en) | 1965-06-21 |
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