AT239220B - Process for the preparation of alkyl-substituted cyanopyridines - Google Patents
Process for the preparation of alkyl-substituted cyanopyridinesInfo
- Publication number
- AT239220B AT239220B AT902662A AT902662A AT239220B AT 239220 B AT239220 B AT 239220B AT 902662 A AT902662 A AT 902662A AT 902662 A AT902662 A AT 902662A AT 239220 B AT239220 B AT 239220B
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- preparation
- cyanopyridines
- substituted
- substituted cyanopyridines
- Prior art date
Links
Landscapes
- Pyridine Compounds (AREA)
Description
<Desc/Clms Page number 1>
EMI1.1
EMI1.2
<Desc/Clms Page number 2>
Als wasserabspaltende Katalysatoren finden vorzugsweise Oxyde oder Phosphate der Elemente der 1lI. Gruppe des Periodensystems Verwendung. Infolge seiner Billigkeit hat sich die Verwendung eines technischen y-Aluminiumoxydkatalysators als besonders zweckmässig erwiesen.
Beispiel l : Als Reaktionsraum diente ein vertikales eisernes Rohr von 1000 mm Länge und 60 mm Durchmesser, das durch einen elektrischen Röhrenofen auf 380 C beheizt wurde. Das Rohr enthielt als
EMI2.1
6 Torr destilliert. Es wurden 125 g 2-Methyl-4-cyanopyridin erhalten (72% d. Th.).
Beispiel 2 : Ein Rohr der im Beispiel 1 genannten Abmessungen enthielt als Katalysator 600 cm3 gekörntes y-Al 0. Bei einer Temperatur von 3600C und einer Strömungsgeschwindigkeit des Ammoniakgases von 100 l/h wurden innerhalb 1 h 100 g 2-Äthylisonicotinsäure in etwa gleichen Portionen eingetragen. Das anfallende Rohprodukt wurde in Äther aufgenommen und der Ätherextrakt mit Natriumsulfat getrocknet. Das so erhaltene Produkt wurde anschliessend bei 840C und unter einem Druck von 6 Torr fraktioniert destilliert. Die Ausbeute an 2-Äthyl-4-cyanopyridin betrug 63 g (73% d. Th.
PATENTANSPRÜCHE :
1. Verfahren zur Herstellung von alkylsubstituierten Cyanopyridinen aus Alkyl-pyridincarbonsäuren oder deren Ammoniumsalzen oder Amiden, dadurch gekennzeichnet, dass man die genannten Verbindungen mit einem Ammoniakgasstrom bei einer Temperatur zwischen 300 und 400 C über einen wasserabspaltenden Katalysator leitet und das dabei entstehende Gemisch aus Cyano-alkylpyridin und Reaktionswasser in bekannter Weise aufarbeitet.
<Desc / Clms Page number 1>
EMI1.1
EMI1.2
<Desc / Clms Page number 2>
The dehydrating catalysts used are preferably oxides or phosphates of the elements of 11. Group of the periodic table usage. As a result of its cheapness, the use of a technical γ-alumina catalyst has proven particularly expedient.
Example 1: A vertical iron tube 1000 mm long and 60 mm in diameter, which was heated to 380 ° C. by an electric tube furnace, served as the reaction chamber. The tube contained as
EMI2.1
6 torr distilled. 125 g of 2-methyl-4-cyanopyridine were obtained (72% of theory).
Example 2: A tube of the dimensions mentioned in Example 1 contained 600 cm3 of granular y-Al O as a catalyst. At a temperature of 3600 ° C. and a flow rate of the ammonia gas of 100 l / h, 100 g of 2-ethylisonicotinic acid were obtained in approximately equal portions within 1 hour registered. The resulting crude product was taken up in ether and the ether extract was dried with sodium sulfate. The product thus obtained was then fractionally distilled at 840 ° C. and under a pressure of 6 Torr. The yield of 2-ethyl-4-cyanopyridine was 63 g (73% of theory.
PATENT CLAIMS:
1. A process for the preparation of alkyl-substituted cyanopyridines from alkyl pyridinecarboxylic acids or their ammonium salts or amides, characterized in that the compounds mentioned are passed with a stream of ammonia gas at a temperature between 300 and 400 C over a dehydrating catalyst and the resulting mixture of cyano- alkylpyridine and water of reaction worked up in a known manner.
Claims (1)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE239220X | 1962-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
AT239220B true AT239220B (en) | 1965-03-25 |
Family
ID=5903798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT902662A AT239220B (en) | 1962-09-18 | 1962-11-16 | Process for the preparation of alkyl-substituted cyanopyridines |
Country Status (1)
Country | Link |
---|---|
AT (1) | AT239220B (en) |
-
1962
- 1962-11-16 AT AT902662A patent/AT239220B/en active
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE2038749B2 (en) | PROCESS FOR THE PRODUCTION OF (METH) ACROLEIN BY OXYDATION OF PROPYLENE OR ISOBUTENE | |
DE1793474A1 (en) | Process for the production of vinyl acetate | |
AT239220B (en) | Process for the preparation of alkyl-substituted cyanopyridines | |
DE2703070A1 (en) | PROCESS FOR THE PREPARATION OF 3-METHYLPYRIDINE | |
DE1543294C3 (en) | Process for the production of acrylic acid or methacrylic acid | |
DE2131561B2 (en) | Process for the preparation of 3,5-dinitrobenzotrifluorides | |
DE1965010C3 (en) | Process for the production of β-picoline | |
AT218515B (en) | Process for the preparation of the 2, 6- and the new 2, 3-dichlorobenzonitrile | |
AT242152B (en) | Process for the production of melamine from urea and / or its thermal decomposition products | |
DE1231249B (en) | Process for the production of imidazole | |
DE3429439A1 (en) | METHOD FOR PRODUCING PANTOLACTONE | |
AT237588B (en) | Process for the production of dicarboxylic acid anhydrides | |
AT256828B (en) | Process for the preparation of 5-nitroimidazole derivatives | |
AT268296B (en) | Process for the preparation of new 6-aminophenyl- and 6-acylaminophenyl-4, 5-dihydropyridazones (3) | |
AT235817B (en) | Process for the production of acetic acid by the catalytic oxidation of propylene | |
DE1058058B (en) | Process for the preparation of alkyl pyridines | |
AT242153B (en) | Process for the production of melamine | |
DE910294C (en) | Process for the production of substituted formamides | |
DE893050C (en) | Process for the preparation of N, N'-diacyl compounds of methylenediamine or alkylidene diamines | |
AT234689B (en) | Process and apparatus for the preparation of 2,2'-dipyridyl | |
DE1059433B (en) | Process for the production of a catalyst for the production of dinitriles of aliphatic and cycloaliphatic dicarboxylic acids | |
AT235264B (en) | Process for the production of acrylonitrile | |
AT133892B (en) | Process for the production of acetic anhydride. | |
DE2020791C3 (en) | Oxidation catalyst and its use | |
AT249653B (en) | Process for reducing resin formation in the manufacture and / or storage of diketene |