AR248275A1 - Un procedimiento de preparacion de eteres de oxima de tienociclo pentanona. - Google Patents

Un procedimiento de preparacion de eteres de oxima de tienociclo pentanona.

Info

Publication number
AR248275A1
AR248275A1 AR92323223A AR32322392A AR248275A1 AR 248275 A1 AR248275 A1 AR 248275A1 AR 92323223 A AR92323223 A AR 92323223A AR 32322392 A AR32322392 A AR 32322392A AR 248275 A1 AR248275 A1 AR 248275A1
Authority
AR
Argentina
Prior art keywords
formula
preparation
fenilo
alquilo
thienocyclopentanones
Prior art date
Application number
AR92323223A
Other languages
English (en)
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Application granted granted Critical
Publication of AR248275A1 publication Critical patent/AR248275A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/08Hydrogen atoms or radicals containing only hydrogen and carbon atoms
    • C07D333/10Thiophene
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

PREPARACION DE COMPUESTOS DE FORMULA (I), DE SUS SALES DE ADICION CON UN ACIDO, Y SUS AMONIOS CUATERNARIOS, EN LA CUAL A, ES UN NUCLEO TIOFENO, SUSTITUIDO O NO POR UNO O VARIOS ALQUILO, ALCOXI, HALOGENO, NITRO, HIDROXI, TRIFLUOROMETILO, Q ES ALQUILENO, R1 Y R2 SON H, ALQUILO, PIRIDILETILO, O FORMAN CON EL ATOMO DE NITROGENO UN HETEROCICLO NITROGENADO SATURADO DE 5 A 7 ATOMOS, QUE INCLUYE O NO UN HETEROATOMO O, S O N, PUDIENDO ESTE ULTIMO SER SUSTITUIDO POR ALQUILO O FENILO, R3 Y R4 SON H, ALQUILO, CICLOALQUILO, TRIFLUOROMETILO O AROMATICO FENILO, TIENILO O FURILO SUSTITUIDOS O NO POR ALQUILO, ALCOXI, HALOGENO, NITRO, HIDROXI, TRIFLUORMETILO, TRIFLUOROMETOXI, CIANO, CARBOXI, CARBAMOILO, N-ALQUILO O N, N DIALQUIL-CARBAMOILO Y ALCOXICARBONILO, O R3 Y R4 FORMAN JUNTOS CON EL ATOMO DE CARBONO UN CICLOALQUILO DONDE SE HACE REACCIONAR SOBRE LA CETONA DE FORMULA (II) LA HIDROXILAMINA DE FORMULA NH2OR EN LA CUAL: R ES -Q-NR1R2 PARA OBTENER DIRECTAMENTE EL COMPUESTO DE FORMULA (I), R ES -Q- X- DONDE X ES HALOGENO, UN AMONIO CUATERNARIO, UN GRUPO SULFATO, PARA OBTENER EL COMPUESTO DE FORMULA (V) SOBRE EL CUAL SE HACE REACCIONAR HNR1R2 O NR1R2R5.
AR92323223A 1991-09-25 1992-09-22 Un procedimiento de preparacion de eteres de oxima de tienociclo pentanona. AR248275A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9111822 1991-09-25

Publications (1)

Publication Number Publication Date
AR248275A1 true AR248275A1 (es) 1995-07-12

Family

ID=9417295

Family Applications (1)

Application Number Title Priority Date Filing Date
AR92323223A AR248275A1 (es) 1991-09-25 1992-09-22 Un procedimiento de preparacion de eteres de oxima de tienociclo pentanona.

Country Status (23)

Country Link
US (1) US5252749A (es)
EP (1) EP0534856B1 (es)
JP (1) JP3162822B2 (es)
KR (1) KR100199848B1 (es)
AR (1) AR248275A1 (es)
AT (1) ATE157360T1 (es)
AU (1) AU652072B2 (es)
BR (1) BR9203744A (es)
CA (1) CA2079016A1 (es)
CZ (1) CZ281936B6 (es)
DE (1) DE69221802T2 (es)
DK (1) DK0534856T3 (es)
ES (1) ES2108098T3 (es)
FI (1) FI106458B (es)
GR (1) GR3025335T3 (es)
HU (1) HU218204B (es)
IL (1) IL103106A (es)
MX (1) MX9205390A (es)
NO (1) NO301327B1 (es)
NZ (1) NZ244452A (es)
PH (1) PH30225A (es)
RU (1) RU2060253C1 (es)
ZA (1) ZA927318B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997044062A1 (en) * 1996-05-23 1997-11-27 Alcon Laboratories, Inc. The use of 5-ht1b/1d agonists to treat ocular pain
JP2005501841A (ja) * 2001-08-01 2005-01-20 バセル ポリオレフィン ジーエムビーエイチ 複素環式ペンタレン誘導体の製造方法
US7432328B2 (en) * 2005-06-14 2008-10-07 Univation Technologies, Llc Enhanced ESCR bimodal HDPE for blow molding applications

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE371190B (es) * 1972-03-24 1974-11-11 Kabi Ab
US3301874A (en) * 1963-12-26 1967-01-31 Sam Joseph Thienocyclopentanone antibacterial agents
SE371193B (es) * 1972-03-24 1974-11-11 Kabi Ab
US4154740A (en) * 1976-03-23 1979-05-15 American Cyanamid Company Substituted tetrahydrobenzothiophenes and method of preparation thereof
FR2471980A1 (fr) * 1979-12-21 1981-06-26 Sanofi Sa Nouveaux derives de l'amino-1 propanol-2, leur procede de preparation et leur application therapeutique
FR2567125B1 (fr) * 1984-07-09 1986-12-05 Lipha Acides dihydro-5,6-4h-cyclopenta (b) thiophenecarboxylique-6, procedes de preparation et medicaments les contenant
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CA2079016A1 (en) 1993-03-26
NZ244452A (en) 1994-08-26
IL103106A (en) 1998-06-15
IL103106A0 (en) 1993-02-21
RU2060253C1 (ru) 1996-05-20
NO923720D0 (no) 1992-09-24
EP0534856A1 (fr) 1993-03-31
FI924281A0 (fi) 1992-09-24
HU9203050D0 (en) 1992-12-28
KR100199848B1 (ko) 1999-06-15
CZ281936B6 (cs) 1997-04-16
HUT62876A (en) 1993-06-28
PH30225A (en) 1997-02-05
GR3025335T3 (en) 1998-02-27
DE69221802D1 (de) 1997-10-02
CZ291892A3 (en) 1993-04-14
DK0534856T3 (da) 1998-04-20
ZA927318B (en) 1994-03-24
ES2108098T3 (es) 1997-12-16
FI924281A (fi) 1993-03-26
MX9205390A (es) 1993-05-01
NO923720L (no) 1993-03-26
ATE157360T1 (de) 1997-09-15
US5252749A (en) 1993-10-12
FI106458B (fi) 2001-02-15
NO301327B1 (no) 1997-10-13
JP3162822B2 (ja) 2001-05-08
AU2454892A (en) 1993-04-01
BR9203744A (pt) 1994-03-29
EP0534856B1 (fr) 1997-08-27
JPH05213932A (ja) 1993-08-24
AU652072B2 (en) 1994-08-11
KR930006001A (ko) 1993-04-20
HU218204B (hu) 2000-06-28
DE69221802T2 (de) 1998-04-02

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