AR241497A1 - {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them - Google Patents
{bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing themInfo
- Publication number
- AR241497A1 AR241497A1 AR30989188A AR30989188A AR241497A1 AR 241497 A1 AR241497 A1 AR 241497A1 AR 30989188 A AR30989188 A AR 30989188A AR 30989188 A AR30989188 A AR 30989188A AR 241497 A1 AR241497 A1 AR 241497A1
- Authority
- AR
- Argentina
- Prior art keywords
- bis
- preparing
- hydroxymethyl
- methyl
- formula
- Prior art date
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE ISOQUINOLINA, DE FORMULA I, DONDE R1 Y R2 REPRESENTAN ALCOXI, R10 REPRESENTA 4-PIRIDILO, FENILO Y FENILALQUILO. SE HACE REACCIONAR UNA 1-¡BIS(HIDROXIMETIL)-METIL¿-6,7- DIALCOXI -1,2,3,4-TETRAHIDROISOQUINOLINA DE FORMULA II, DONDE R1 Y R2 IDEM ARRIBA INDICADOS, CON UN ALDEHIDO DE FORMULA II, EN LA QUE R10 TIENE LOS SIGNIFICADOS INDICADOS, O CN UN DIALQUIL -ACETAL DE ESTE, Y SI SE DESEA, EL COMPUESTO OBTENIDO DE FORMULA I SE TRANSFORMA EN SU SAL.PROCEDURE FOR PREPARING NEW ISOQUINOLINE DERIVATIVES, FORMULA I, WHERE R1 AND R2 REPRESENT ALCOXI, R10 REPRESENTS 4-PIRIDYL, FENYL AND FENYLALKYL. A 1-¡BIS (HYDROXIMETIL) -METIL¿-6,7- DIALCOXI -1,2,3,4-TETRAHIDROISOQUINOLINA OF FORMULA II, WHERE R1 AND R2 IDEM ARE INDICATED ABOVE, WITH A FORMULA II ALDEHYDE, IS REACTED WHICH R10 HAS THE INDICATED MEANINGS, OR A DIALKYL -ACETAL OF THIS, AND IF DESIRED, THE COMPOUND OBTAINED FROM FORMULA I IS TRANSFORMED INTO ITS SALT.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU833654A HU190458B (en) | 1983-10-25 | 1983-10-25 | Process for preparing /1,3/ oxazino /4,3-a/ isoquinoline-derivatives |
HU833651A HU189348B (en) | 1983-10-25 | 1983-10-25 | Process for producing l-/bis/hydroxy-methyl/-methyl/-3,4-dihydro- or 1,2,3,4-tetrahydro-isoquinolin derivatives |
HU833655A HU186810B (en) | 1983-10-25 | 1983-10-25 | Process for producing 2h-azeto/2,1-a/ isoquinoline-derivatives |
HU833653A HU189764B (en) | 1983-10-25 | 1983-10-25 | Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives |
HU833652A HU189765B (en) | 1983-10-25 | 1983-10-25 | Process for preparing n-substituted 1-(bis (hydroxy-metiol)-methyl)-isoquinoline-derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
AR241497A1 true AR241497A1 (en) | 1992-07-31 |
Family
ID=32873013
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR29837684A AR241490A1 (en) | 1983-10-25 | 1984-10-25 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
AR30989188A AR241497A1 (en) | 1983-10-25 | 1988-01-22 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
AR30989088A AR241494A1 (en) | 1983-10-25 | 1988-01-22 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
AR30989288A AR241496A1 (en) | 1983-10-25 | 1988-01-22 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR29837684A AR241490A1 (en) | 1983-10-25 | 1984-10-25 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR30989088A AR241494A1 (en) | 1983-10-25 | 1988-01-22 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
AR30989288A AR241496A1 (en) | 1983-10-25 | 1988-01-22 | {bis(hydroxymethyl)-methyl]-isoquinoline derivatives, process for preparing them and pharmaceutical compositions containing them |
Country Status (1)
Country | Link |
---|---|
AR (4) | AR241490A1 (en) |
-
1984
- 1984-10-25 AR AR29837684A patent/AR241490A1/en active
-
1988
- 1988-01-22 AR AR30989188A patent/AR241497A1/en active
- 1988-01-22 AR AR30989088A patent/AR241494A1/en active
- 1988-01-22 AR AR30989288A patent/AR241496A1/en active
Also Published As
Publication number | Publication date |
---|---|
AR241494A1 (en) | 1992-07-31 |
AR241496A1 (en) | 1992-07-31 |
AR241490A1 (en) | 1992-07-31 |
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