AR241179A1 - Un procedimiento para preparar acidos-2-hidroxi-4-alquildenciclohexanoalcanoicos que tienen un sustituyente acido mercaptoalcanoico en la posicion 3,y los esteres de alquilo(c1-c4)de los mismos. - Google Patents

Un procedimiento para preparar acidos-2-hidroxi-4-alquildenciclohexanoalcanoicos que tienen un sustituyente acido mercaptoalcanoico en la posicion 3,y los esteres de alquilo(c1-c4)de los mismos.

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Publication number
AR241179A1
AR241179A1 AR86304974A AR30497486A AR241179A1 AR 241179 A1 AR241179 A1 AR 241179A1 AR 86304974 A AR86304974 A AR 86304974A AR 30497486 A AR30497486 A AR 30497486A AR 241179 A1 AR241179 A1 AR 241179A1
Authority
AR
Argentina
Prior art keywords
alcoxy
hydroxy
formula
acid
acids
Prior art date
Application number
AR86304974A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of AR241179A1 publication Critical patent/AR241179A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/132Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings
    • C07C53/134Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing rings monocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/10Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C323/11Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/16Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/38Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D303/40Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR ACIDOS 2-HIDROXI-4- ALQUILIDENCICLOHEXANOALCANOICOS QUE TIENE UN SUSTITUYENTES ACIDO MERCAPTOALCANOICO EN LA POSICION 3, Y A LOS ESTERES DE ALQUILO CORRESPONDIENTES DELOS ACIDOS, QUE TIENEN LA FORMULA (I), DONDE M ES UN ENTERO DE 1 A 5; N ES UN ENTERO DE 0 A 2, R ES ALQUILO; Y ES HIDROXI O ALCOXI; Z ES HIDROXI O ALCOXI, PORQUE CONSISTE EN HACER REACCIONAR UN EPOXIDO DE FORMULA (II), DONDE M Y R SE DEFINEN COMO ANTES Y Z' ES ALCOXI CON UN DERIVADO DE UN ACIDO MERCAPTOALCANOICO DE FORMULA (III), DONDE N ES UN ENTERO DE 0 A 2 E Y' ES ALCOXI EN UN DISOLVENTE APROPIADO EN PRESENCIA DE UNA BASE, SEGUIDA OPCIONALMENTE, CUANDO Y' O Z' SON ALCOXI DE TRATAMIENTO CON UNA BASE INORGANICA FUERTE SEGUIDA DE LA ACIDULACION CON UN ACIDO FUERTE PARA DAR LOS COMPTOS DONDE Y O Z SON GRUPOS -OH.
AR86304974A 1985-08-23 1986-08-20 Un procedimiento para preparar acidos-2-hidroxi-4-alquildenciclohexanoalcanoicos que tienen un sustituyente acido mercaptoalcanoico en la posicion 3,y los esteres de alquilo(c1-c4)de los mismos. AR241179A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/768,769 US4622422A (en) 1985-08-23 1985-08-23 Cyclohexanealkanoic acids

Publications (1)

Publication Number Publication Date
AR241179A1 true AR241179A1 (es) 1992-01-31

Family

ID=25083435

Family Applications (1)

Application Number Title Priority Date Filing Date
AR86304974A AR241179A1 (es) 1985-08-23 1986-08-20 Un procedimiento para preparar acidos-2-hidroxi-4-alquildenciclohexanoalcanoicos que tienen un sustituyente acido mercaptoalcanoico en la posicion 3,y los esteres de alquilo(c1-c4)de los mismos.

Country Status (21)

Country Link
US (1) US4622422A (es)
EP (1) EP0213547B1 (es)
JP (1) JPS6248663A (es)
KR (1) KR900002821B1 (es)
CN (1) CN1019195B (es)
AR (1) AR241179A1 (es)
AT (1) ATE59382T1 (es)
AU (1) AU605466B2 (es)
CA (1) CA1283250C (es)
DE (1) DE3676594D1 (es)
DK (1) DK401786A (es)
ES (1) ES2001573A6 (es)
FI (1) FI84263C (es)
GR (1) GR862164B (es)
HU (1) HU196744B (es)
IL (1) IL79770A0 (es)
NO (1) NO164533C (es)
NZ (1) NZ217249A (es)
PH (1) PH22129A (es)
PT (1) PT83238B (es)
ZA (1) ZA866216B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748274A (en) * 1986-11-07 1988-05-31 Merrell Dow Pharmaceuticals Inc. 4-hydroxy-4-(substituted alkenyl)cyclohexanecarboxylic acids
US6863111B1 (en) 2000-10-03 2005-03-08 Tser-Wen Chou Positive engagement end stop for window covering systems
JP4746511B2 (ja) * 2006-10-23 2011-08-10 株式会社東芝 固体高分子型燃料電池システム

Also Published As

Publication number Publication date
NO164533B (no) 1990-07-09
CN86105165A (zh) 1987-04-08
GR862164B (en) 1986-12-23
KR900002821B1 (ko) 1990-05-01
PT83238A (en) 1986-09-01
FI863410A (fi) 1987-02-24
HUT43813A (en) 1987-12-28
EP0213547A1 (en) 1987-03-11
DK401786A (da) 1987-02-24
JPS6248663A (ja) 1987-03-03
FI84263C (fi) 1991-11-11
KR870002068A (ko) 1987-03-28
CA1283250C (en) 1991-04-16
FI863410A0 (fi) 1986-08-22
CN1019195B (zh) 1992-11-25
ES2001573A6 (es) 1988-06-01
EP0213547B1 (en) 1990-12-27
ATE59382T1 (de) 1991-01-15
ZA866216B (en) 1987-03-25
US4622422A (en) 1986-11-11
AU6164786A (en) 1987-02-26
HU196744B (en) 1989-01-30
PT83238B (pt) 1988-07-01
NZ217249A (en) 1989-11-28
NO863388L (no) 1987-02-24
AU605466B2 (en) 1991-01-17
NO863388D0 (no) 1986-08-22
DK401786D0 (da) 1986-08-22
NO164533C (no) 1990-10-17
PH22129A (en) 1988-06-01
FI84263B (fi) 1991-07-31
DE3676594D1 (de) 1991-02-07
IL79770A0 (en) 1986-11-30

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