AR223694A1 - Un procedimiento para preparar vindesina y procedimiento para preparar c-3-carboximida de n-(trifenil-fosforanilo)de 4-desacetilvincaleucoblastina de aplicacion en dicho procedimiento - Google Patents

Un procedimiento para preparar vindesina y procedimiento para preparar c-3-carboximida de n-(trifenil-fosforanilo)de 4-desacetilvincaleucoblastina de aplicacion en dicho procedimiento

Info

Publication number: AR223694A1
Authority: AR; Argentina
Prior art keywords: procedure; prepare; phosphoranil; desacetilvincaleucoblastina; carboximide
Prior art date: 1979-01-15

Application number

AR279615A

Other languages

English (en)

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-15

Filing date

1980-01-14

Publication date

1981-09-15

1980-01-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1981-09-15 Application granted granted Critical

1981-09-15 Publication of AR223694A1 publication Critical patent/AR223694A1/es

Links

NDMPLJNOPCLANR-UHFFFAOYSA-N 3,4-dihydroxy-15-(4-hydroxy-18-methoxycarbonyl-5,18-seco-ibogamin-18-yl)-16-methoxy-1-methyl-6,7-didehydro-aspidospermidine-3-carboxylic acid methyl ester Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 NDMPLJNOPCLANR-UHFFFAOYSA-N 0.000 title 1
UGGWPQSBPIFKDZ-KOTLKJBCSA-N vindesine Chemical compound C([C@@H](C[C@]1(C(=O)OC)C=2C(=CC3=C([C@]45[C@H]([C@@]([C@H](O)[C@]6(CC)C=CCN([C@H]56)CC4)(O)C(N)=O)N3C)C=2)OC)C[C@@](C2)(O)CC)N2CCC2=C1N=C1[C]2C=CC=C1 UGGWPQSBPIFKDZ-KOTLKJBCSA-N 0.000 title 1
229960004355 vindesine Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)

AR279615A 1979-01-15 1980-01-14 Un procedimiento para preparar vindesina y procedimiento para preparar c-3-carboximida de n-(trifenil-fosforanilo)de 4-desacetilvincaleucoblastina de aplicacion en dicho procedimiento AR223694A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/003,442 US4210584A (en)	1979-01-15	1979-01-15	Vindesine synthesis

Publications (1)

Publication Number	Publication Date
AR223694A1 true AR223694A1 (es)	1981-09-15

Family

ID=21705894

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AR279615A AR223694A1 (es)	1979-01-15	1980-01-14	Un procedimiento para preparar vindesina y procedimiento para preparar c-3-carboximida de n-(trifenil-fosforanilo)de 4-desacetilvincaleucoblastina de aplicacion en dicho procedimiento

Country Status (34)

Country	Link
US (1)	US4210584A (es)
EP (1)	EP0014053B1 (es)
JP (1)	JPS5598195A (es)
KR (1)	KR830002840B1 (es)
AR (1)	AR223694A1 (es)
AT (1)	AT371127B (es)
AU (1)	AU5452280A (es)
BE (1)	BE881078A (es)
BG (1)	BG33295A3 (es)
CA (1)	CA1148945A (es)
CH (1)	CH645383A5 (es)
CS (1)	CS214691B2 (es)
DD (1)	DD148779A5 (es)
DE (1)	DE3065852D1 (es)
DK (1)	DK148961C (es)
ES (2)	ES8101611A1 (es)
FI (1)	FI800071A (es)
FR (1)	FR2446290A1 (es)
GB (1)	GB2040934B (es)
GR (1)	GR72464B (es)
HU (1)	HU182083B (es)
IE (1)	IE49376B1 (es)
IL (1)	IL59119A (es)
IT (1)	IT1140506B (es)
LU (1)	LU82079A1 (es)
MY (1)	MY8500570A (es)
NZ (1)	NZ192574A (es)
PH (1)	PH15343A (es)
PL (1)	PL124350B1 (es)
PT (1)	PT70681A (es)
RO (1)	RO77532A (es)
SU (1)	SU906381A3 (es)
YU (1)	YU5680A (es)
ZA (1)	ZA80157B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60112895A (ja) *	1983-11-24	1985-06-19	Nippon Oil & Fats Co Ltd	金属圧延用潤滑油
FR2651348B1 (es) *	1989-08-04	1993-01-22	Adir
TW258739B (es) *	1992-04-04	1995-10-01	Hoechst Ag
JP2003513756A (ja) *	1999-11-12	2003-04-15	アンジオテックファーマシューティカルズ，インコーポレイテッド	放射性治療と細胞周期インヒビターとの組合せの組成物
CA2511521C (en)	2002-12-30	2012-02-07	Angiotech International Ag	Drug delivery from rapid gelling polymer composition
CN106831826B (zh) *	2016-12-31	2018-07-06	广州白云山汉方现代药业有限公司	一种从长春花中制备长春地辛的方法
CN106831827B (zh) *	2016-12-31	2019-03-29	广州白云山汉方现代药业有限公司	一种长春地辛的分离纯化方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2756235A (en) *	1954-08-27	1956-07-24	Lilly Co Eli	Method of producing lysergic acid amide

1979
- 1979-01-15 US US06/003,442 patent/US4210584A/en not_active Expired - Lifetime
1980
- 1980-01-10 PT PT70681A patent/PT70681A/pt unknown
- 1980-01-10 FI FI800071A patent/FI800071A/fi not_active Application Discontinuation
- 1980-01-10 DE DE8080300095T patent/DE3065852D1/de not_active Expired
- 1980-01-10 CA CA000343455A patent/CA1148945A/en not_active Expired
- 1980-01-10 GB GB8000870A patent/GB2040934B/en not_active Expired
- 1980-01-10 GR GR60929A patent/GR72464B/el unknown
- 1980-01-10 BE BE1/9677A patent/BE881078A/fr not_active IP Right Cessation
- 1980-01-10 YU YU00056/80A patent/YU5680A/xx unknown
- 1980-01-10 CS CS80235A patent/CS214691B2/cs unknown
- 1980-01-10 ZA ZA00800157A patent/ZA80157B/xx unknown
- 1980-01-10 AU AU54522/80A patent/AU5452280A/en not_active Abandoned
- 1980-01-10 FR FR8000466A patent/FR2446290A1/fr active Granted
- 1980-01-10 EP EP80300095A patent/EP0014053B1/en not_active Expired
- 1980-01-10 NZ NZ192574A patent/NZ192574A/xx unknown
- 1980-01-11 HU HU8052A patent/HU182083B/hu not_active IP Right Cessation
- 1980-01-11 JP JP250480A patent/JPS5598195A/ja active Granted
- 1980-01-11 AT AT0014080A patent/AT371127B/de not_active IP Right Cessation
- 1980-01-13 IL IL59119A patent/IL59119A/xx unknown
- 1980-01-14 CH CH28780A patent/CH645383A5/fr not_active IP Right Cessation
- 1980-01-14 BG BG8046233A patent/BG33295A3/xx unknown
- 1980-01-14 DK DK14780A patent/DK148961C/da not_active IP Right Cessation
- 1980-01-14 IT IT19210/80A patent/IT1140506B/it active
- 1980-01-14 ES ES487682A patent/ES8101611A1/es not_active Expired
- 1980-01-14 IE IE60/80A patent/IE49376B1/en unknown
- 1980-01-14 PL PL1980221359A patent/PL124350B1/pl unknown
- 1980-01-14 LU LU82079A patent/LU82079A1/fr unknown
- 1980-01-14 AR AR279615A patent/AR223694A1/es active
- 1980-01-14 SU SU802872553A patent/SU906381A3/ru active
- 1980-01-14 PH PH23506A patent/PH15343A/en unknown
- 1980-01-15 DD DD80218466A patent/DD148779A5/de unknown
- 1980-01-15 KR KR1019800000134A patent/KR830002840B1/ko active
- 1980-01-15 RO RO8099874A patent/RO77532A/ro unknown
- 1980-01-15 ES ES487726A patent/ES487726A0/es active Granted
1985
- 1985-12-30 MY MY570/85A patent/MY8500570A/xx unknown

Also Published As

Publication number	Publication date
DK14780A (da)	1980-07-16
GR72464B (es)	1983-11-10
IL59119A (en)	1983-06-15
DK148961B (da)	1985-12-02
ATA14080A (de)	1982-10-15
ES487682A0 (es)	1980-12-16
GB2040934B (en)	1983-03-09
DK148961C (da)	1986-05-20
HU182083B (en)	1983-12-28
ES8101612A1 (es)	1980-12-16
IE49376B1 (en)	1985-10-02
PL221359A1 (es)	1980-12-15
YU5680A (en)	1983-02-28
US4210584A (en)	1980-07-01
PT70681A (en)	1980-02-01
JPS5598195A (en)	1980-07-25
FI800071A (fi)	1980-07-16
BG33295A3 (en)	1983-01-14
IE800060L (en)	1980-07-15
PL124350B1 (en)	1983-01-31
IL59119A0 (en)	1980-05-30
RO77532A (ro)	1982-02-26
CA1148945A (en)	1983-06-28
IT1140506B (it)	1986-10-01
PH15343A (en)	1982-12-02
DD148779A5 (de)	1981-06-10
AT371127B (de)	1983-06-10
KR830002840B1 (ko)	1983-12-27
ES8101611A1 (es)	1980-12-16
SU906381A3 (ru)	1982-02-15
ES487726A0 (es)	1980-12-16
EP0014053B1 (en)	1983-12-14
DE3065852D1 (en)	1984-01-19
AU5452280A (en)	1980-07-24
KR830001961A (ko)	1983-05-21
CS214691B2 (en)	1982-05-28
FR2446290B1 (es)	1983-06-24
GB2040934A (en)	1980-09-03
JPS6332796B2 (es)	1988-07-01
FR2446290A1 (fr)	1980-08-08
ZA80157B (en)	1981-08-26
LU82079A1 (fr)	1980-04-23
IT8019210A0 (it)	1980-01-14
EP0014053A1 (en)	1980-08-06
MY8500570A (en)	1985-12-31
NZ192574A (en)	1982-03-16
CH645383A5 (fr)	1984-09-28
BE881078A (fr)	1980-07-10

Publication	Publication Date	Title
TR21804A (tr)	1985-07-19	Zirai uereler ve izouereler
NO803330L (no)	1981-06-01	Elektrolysoer og fremgangsmaate for elektrolysering
ES502384A0 (es)	1982-04-01	Perfeccionamientos en aparatos para abarcar y elaborar sena-les electricas
IT1092432B (it)	1985-07-12	Impianto e procedimento in doppio per copiatrici a pre-inserimento
FR2450947B2 (fr)	1985-12-27	Perfectionnements aux turbomachines
ES492935A0 (es)	1980-12-16	Perfeccionamientos en misiles
MX147863A (es)	1983-01-25	Mejoras en aparato para fabricar pizzas y similares
TR20266A (tr)	1980-12-08	Ensektisid bilesimler ve bunlarin hazirlanmasi
AR225926A1 (es)	1982-05-14	Pieza mecanica y procedimiento para su fabricacion
ES521744A0 (es)	1984-01-16	Procedimiento para preparar ciclohexanol y ciclohexanona.
MX149697A (es)	1983-12-13	Mejoras en hilo combinado y metodo para formarlo
NZ184263A (en)	1979-12-11	N-(amino-alkyl-amino)-benzamides and pharmaceutical compositions
BR7909007A (pt)	1981-04-14	Turbocarregador e adaptacoes para o mesmo
AR223694A1 (es)	1981-09-15	Un procedimiento para preparar vindesina y procedimiento para preparar c-3-carboximida de n-(trifenil-fosforanilo)de 4-desacetilvincaleucoblastina de aplicacion en dicho procedimiento
IT1141137B (it)	1986-10-01	Peptidi e composizioni farmaceutiche che li contengono
DK465880A (da)	1981-05-27	Tekstil-bloedgoerende og antistatiske forbindelser
AR225761A1 (es)	1982-04-30	Naftilaminas aciladas y procedimiento para su obtencion
BE882010A (fr)	1980-06-16	Tetrahydrobenzothiazolylimidazolidinones et leur utilisation
IT1143133B (it)	1986-10-22	Composizioni analgesiche e miotonolitiche
ES252342Y (es)	1981-05-16	Disposicion para medias y similares
TR19891A (tr)	1980-04-09	Ensektisid ve akarisid maddeler
MX6013E (es)	1984-09-24	Procedimiento para preparar arilalquil y ariloxi-alquil-fosfonatos
ZA777358B (en)	1979-07-25	Pharmaceutical compositions and methods
DK94680A (da)	1980-09-07	Arthropodicide og nematodicide carbamoylsulfider
ATA554779A (de)	1984-06-15	Back- und grillgeraet