AR106442A1 - ANTI-IL2 ANTIBODIES, COMPOSITIONS AND USES - Google Patents

ANTI-IL2 ANTIBODIES, COMPOSITIONS AND USES

Info

Publication number
AR106442A1
AR106442A1 ARP160103221A ARP160103221A AR106442A1 AR 106442 A1 AR106442 A1 AR 106442A1 AR P160103221 A ARP160103221 A AR P160103221A AR P160103221 A ARP160103221 A AR P160103221A AR 106442 A1 AR106442 A1 AR 106442A1
Authority
AR
Argentina
Prior art keywords
antibodies
provides
compositions
immunosuppression
encode
Prior art date
Application number
ARP160103221A
Other languages
Spanish (es)
Original Assignee
Pfizer
Univ Leland Stanford Junior
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer, Univ Leland Stanford Junior, Univ California filed Critical Pfizer
Publication of AR106442A1 publication Critical patent/AR106442A1/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente proporciona anticuerpos o sus porciones de unión a antígeno, los cuales se unen específicamente a IL 2 y reducen la afinidad de unión de IL 2 a IL 2Ra e IL 2Rb. Proporciona además un método para obtener dichos anticuerpos y los ácidos nucleicos que los codifican. Se relaciona además con composiciones y métodos terapéuticos para usar estos anticuerpos para el tratamiento y/o prevención de enfermedades, trastornos o condiciones autoinmunes y para inmunosupresión, incluyendo no taxativamente, la administración de un complejo que comprende el anticuerpo e IL 2. Vector. Célula.This provides antibodies or their antigen binding portions, which specifically bind to IL 2 and reduce the binding affinity of IL 2 to IL 2Ra and IL 2Rb. It also provides a method to obtain said antibodies and the nucleic acids that encode them. It also relates to therapeutic compositions and methods for using these antibodies for the treatment and / or prevention of autoimmune diseases, disorders or conditions and for immunosuppression, including but not limited to, the administration of a complex comprising the antibody and IL 2. Vector. Cell.

ARP160103221A 2015-10-23 2016-10-21 ANTI-IL2 ANTIBODIES, COMPOSITIONS AND USES AR106442A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562245600P 2015-10-23 2015-10-23

Publications (1)

Publication Number Publication Date
AR106442A1 true AR106442A1 (en) 2018-01-17

Family

ID=61159867

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP160103221A AR106442A1 (en) 2015-10-23 2016-10-21 ANTI-IL2 ANTIBODIES, COMPOSITIONS AND USES

Country Status (1)

Country Link
AR (1) AR106442A1 (en)

Similar Documents

Publication Publication Date Title
CL2019002566A1 (en) Anti-phf-tau antibodies and their uses.
CL2020003028A1 (en) Anti-cd33 antibodies, anti-cd33 / anti-cd3 bispecific antibodies and their uses.
CO2018012415A2 (en) Specific binding proteins and uses thereof
AR109276A1 (en) ANTI-hCTLA 4 ANTIBODIES
CL2020001854A1 (en) Gprc5d binding antibodies.
EA201992131A1 (en) HIGH-AFFINE SPECIFIC TO MAGE-A1 TCR AND THEIR APPLICATION
AR105444A1 (en) THERAPEUTIC ANTIBODIES THAT JOIN THE PROTEIN CODIFIED BY THE GENOPHYPE ACTIVATION GEN 3 (LAG3)
MX2021011697A (en) Anti-cd3 antibodies, anti-cd123 antibodies and bispecific antibodies specifically binding to cd3 and/or cd123.
UY36687A (en) ANTIBODIES AGAINST OX40 AND ITS USES
PE20210488A1 (en) ANTIBODIES SPECIFIC TO GUCY2C AND ITS USES
CR20170079A (en) UNION AGENTS TO CD123 AND USES OF THESE
ECSP19011185A (en) Bispecific antibody-like binding proteins that specifically bind CD3 and CD123
EA201891732A1 (en) BISPECIFIC BINDING PROTEINS FOR PD-L1 AND KDR
BR112017006468A2 (en) bispecific antibody, pharmaceutical composition, kit, use of a combination of a bispecific antibody and cancer treatment method
PE20210708A1 (en) ANTIBODIES SPECIFIC TO CD70 AND THEIR USES
CL2021000909A1 (en) Stabilizing Trem2 Antibodies
CL2020001334A1 (en) Antibodies that bind to the envelope protein of the Zika virus and their uses. (divisional request 201900999)
CL2020001629A1 (en) Hla-a2 / wt1 binding antibodies.
MX2020009130A (en) Therapeutic anti-spla2-gib antibodies and the uses thereof.
AR108975A1 (en) ANTIBODIES WITH LOW IMMUNOGENICITY AND ITS USES
CO2019010164A2 (en) Antibodies that bind steap-1
AR106442A1 (en) ANTI-IL2 ANTIBODIES, COMPOSITIONS AND USES
UY38432A (en) MONOCLONAL ANTIBODY SPECIFICALLY BINDING TO CD20 ANTIGEN
MX2020004026A (en) Monoclonal antibody to il-5r¿.
AR117579A1 (en) SPECIFIC ANTIBODIES FOR GUCY2C AND ITS USES

Legal Events

Date Code Title Description
FB Suspension of granting procedure