AR100618A1 - Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido - Google Patents
Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducidoInfo
- Publication number
- AR100618A1 AR100618A1 ARP150101653A ARP150101653A AR100618A1 AR 100618 A1 AR100618 A1 AR 100618A1 AR P150101653 A ARP150101653 A AR P150101653A AR P150101653 A ARP150101653 A AR P150101653A AR 100618 A1 AR100618 A1 AR 100618A1
- Authority
- AR
- Argentina
- Prior art keywords
- dissolved oxygen
- human albumin
- albumin
- oxygen level
- preparation procedure
- Prior art date
Links
- 102000008100 Human Serum Albumin Human genes 0.000 title abstract 4
- 108091006905 Human Serum Albumin Proteins 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 3
- 229910052760 oxygen Inorganic materials 0.000 title abstract 3
- 239000001301 oxygen Substances 0.000 title abstract 3
- 102000009027 Albumins Human genes 0.000 abstract 3
- 108010088751 Albumins Proteins 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/765—Serum albumin, e.g. HSA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Procedimiento de preparación de una solución de albúmina humana, más en particular, se refiere a un procedimiento que comprende una etapa de reducción del oxígeno disuelto en dicha solución de albúmina hasta una concentración igual o menor que 0,5 ppm. Con el procedimiento es posible obtener una solución de albúmina humana con un estado redox más cercano al estado redox de la albúmina presente en el plasma humano. Reivindicación 13: Composición que comprende albúmina humana preparada mediante un procedimiento según cualquiera de las reivindicaciones 1 a 12, caracterizada porque presenta una concentración de oxígeno disuelto igual o menor que 0,5 ppm. Reivindicación 14: Uso de una composición que comprende albúmina, según la reivindicación 13, para la preparación de un medicamento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES201430824A ES2524516B1 (es) | 2014-05-29 | 2014-05-29 | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR100618A1 true AR100618A1 (es) | 2016-10-19 |
Family
ID=52003454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP150101653A AR100618A1 (es) | 2014-05-29 | 2015-05-27 | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10350274B2 (es) |
| EP (1) | EP2952203B9 (es) |
| JP (3) | JP2015224251A (es) |
| KR (1) | KR101960729B1 (es) |
| CN (1) | CN105315362B (es) |
| AR (1) | AR100618A1 (es) |
| AU (1) | AU2015202413B2 (es) |
| BR (1) | BR102015012091A8 (es) |
| CA (1) | CA2890642C (es) |
| CL (1) | CL2015001446A1 (es) |
| ES (2) | ES2524516B1 (es) |
| HU (1) | HUE031823T2 (es) |
| IL (1) | IL238898B (es) |
| MX (1) | MX362869B (es) |
| MY (1) | MY171771A (es) |
| NZ (1) | NZ708537A (es) |
| PL (1) | PL2952203T3 (es) |
| PT (1) | PT2952203T (es) |
| RU (1) | RU2657578C2 (es) |
| SG (1) | SG10201504137PA (es) |
| TW (1) | TWI607018B (es) |
| ZA (1) | ZA201503539B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2524516B1 (es) * | 2014-05-29 | 2015-03-31 | Grifols Worldwide Operations Limited | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
| EP3995141B1 (en) | 2016-04-28 | 2024-01-03 | Alkahest, Inc. | Plasma fractions as therapy for thymic cancer |
| UA126232C2 (uk) | 2016-08-18 | 2022-09-07 | Алкахест, Інк. | Спосіб лікування когнітивного розладу, пов'язаного зі старінням, та набір, що містить фракцію плазми крові |
| CA3061194A1 (en) | 2017-04-26 | 2018-11-01 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| WO2020018343A1 (en) | 2018-07-20 | 2020-01-23 | Alkahest, Inc. | Dosing regimen for treatment of cognitive and motor impairments with blood plasma and blood plasma products |
| CN109627322A (zh) * | 2019-01-07 | 2019-04-16 | 中国科学院过程工程研究所 | 一种从Cohn组分Ⅴ上清中分离纯化人血清白蛋白的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4094965A (en) * | 1977-04-01 | 1978-06-13 | New England Nuclear Corporation | Diagnostic agents containing albumin and method for making same |
| SE9301581D0 (sv) * | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Protein formulation |
| JPH07126182A (ja) * | 1993-10-27 | 1995-05-16 | Green Cross Corp:The | 組換えヒト血清アルブミン製剤の滅菌方法 |
| SE9402119D0 (sv) * | 1994-06-16 | 1994-06-16 | Pharmacia Ab | Solution |
| US5766582A (en) * | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| JP4254117B2 (ja) * | 2001-03-27 | 2009-04-15 | ニプロ株式会社 | アルブミン溶液収容プラスチック容器 |
| EP1245217B1 (en) * | 2001-03-27 | 2009-10-28 | Nipro Corporation | Plastic container containing albumin solution |
| JP4225416B2 (ja) * | 2001-06-29 | 2009-02-18 | 旭化成ファーマ株式会社 | タンパク質製剤の安定性を改善する方法 |
| US7252799B2 (en) * | 2001-08-31 | 2007-08-07 | Clearant, Inc. | Methods for sterilizing preparations containing albumin |
| ES2270245T3 (es) * | 2003-08-28 | 2007-04-01 | Nipro Corporation | Vehiculo de oxigeno artificial y su metodo de produccion. |
| ES2391657T3 (es) * | 2006-02-07 | 2012-11-28 | Shire Human Genetic Therapies, Inc. | Composiciones estabilizadas de proteínas que tienen un resto tiol libre |
| ES2294976B1 (es) * | 2007-11-12 | 2008-12-16 | Grifols, S.A. | "procedimiento de obtencion de albumina humana de alta eficacia para su uso en terapia de detoxificacion". |
| JP5990880B2 (ja) * | 2011-08-31 | 2016-09-14 | 東レ株式会社 | 有用タンパク質組成物およびその製造方法 |
| CN102816230B (zh) * | 2012-08-27 | 2014-02-12 | 同路生物制药股份有限公司 | 人血白蛋白的制备方法 |
| ES2524516B1 (es) * | 2014-05-29 | 2015-03-31 | Grifols Worldwide Operations Limited | Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido |
-
2014
- 2014-05-29 ES ES201430824A patent/ES2524516B1/es not_active Expired - Fee Related
-
2015
- 2015-04-01 HU HUE15382164A patent/HUE031823T2/en unknown
- 2015-04-01 ES ES15382164.0T patent/ES2601137T3/es active Active
- 2015-04-01 EP EP15382164.0A patent/EP2952203B9/en active Active
- 2015-04-01 PT PT153821640T patent/PT2952203T/pt unknown
- 2015-04-01 PL PL15382164T patent/PL2952203T3/pl unknown
- 2015-05-01 CA CA2890642A patent/CA2890642C/en active Active
- 2015-05-06 AU AU2015202413A patent/AU2015202413B2/en active Active
- 2015-05-15 MY MYPI2015701570A patent/MY171771A/en unknown
- 2015-05-18 RU RU2015118453A patent/RU2657578C2/ru active
- 2015-05-19 IL IL238898A patent/IL238898B/en active IP Right Grant
- 2015-05-20 ZA ZA2015/03539A patent/ZA201503539B/en unknown
- 2015-05-21 MX MX2015006407A patent/MX362869B/es active IP Right Grant
- 2015-05-22 CN CN201510264800.9A patent/CN105315362B/zh active Active
- 2015-05-26 SG SG10201504137PA patent/SG10201504137PA/en unknown
- 2015-05-26 BR BR102015012091A patent/BR102015012091A8/pt not_active IP Right Cessation
- 2015-05-26 TW TW104116876A patent/TWI607018B/zh not_active IP Right Cessation
- 2015-05-27 AR ARP150101653A patent/AR100618A1/es active IP Right Grant
- 2015-05-27 NZ NZ708537A patent/NZ708537A/en not_active IP Right Cessation
- 2015-05-28 CL CL2015001446A patent/CL2015001446A1/es unknown
- 2015-05-28 US US14/724,649 patent/US10350274B2/en active Active
- 2015-05-28 JP JP2015108569A patent/JP2015224251A/ja active Pending
- 2015-05-28 KR KR1020150074568A patent/KR101960729B1/ko active IP Right Grant
-
2018
- 2018-04-27 JP JP2018086673A patent/JP2018115210A/ja active Pending
-
2020
- 2020-04-20 JP JP2020074749A patent/JP2020111614A/ja active Pending
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Legal Events
| Date | Code | Title | Description |
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| FG | Grant, registration |