AR100234A1 - Método para la producción de l-lisina en el que se utiliza una bacteria alcalifílica - Google Patents
Método para la producción de l-lisina en el que se utiliza una bacteria alcalifílicaInfo
- Publication number
- AR100234A1 AR100234A1 ARP150101300A ARP150101300A AR100234A1 AR 100234 A1 AR100234 A1 AR 100234A1 AR P150101300 A ARP150101300 A AR P150101300A AR P150101300 A ARP150101300 A AR P150101300A AR 100234 A1 AR100234 A1 AR 100234A1
- Authority
- AR
- Argentina
- Prior art keywords
- bacteria
- alkalifil
- lisine
- production
- alkalylic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se encontró que mediante la selección de bacterias alcalifílicas en un medio que contiene S-2-aminoetil-L-cisteína y L-treonina, puede obtenerse una bacteria alcalifílica que sobreproduce L-lisina. Reivindicación 3: Aspartato quinasas resistentes a retroalimentación de acuerdo con la reivindicación 2, caracterizadas porque son polipéptidos con una secuencia de acuerdo a la SEQ ID Nº 12 con la condición de que por lo menos está presente una, preferentemente precisamente una, de las siguientes mutaciones: D274Y, A279E, S301Y, T308l, T311I, G359D.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14166666.9A EP2940144A1 (de) | 2014-04-30 | 2014-04-30 | Verfahren zur Produktion von L-Lysin unter Verwendung eines alkaliphilen Bakteriums |
Publications (1)
Publication Number | Publication Date |
---|---|
AR100234A1 true AR100234A1 (es) | 2016-09-21 |
Family
ID=50677978
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP150101300A AR100234A1 (es) | 2014-04-30 | 2015-04-29 | Método para la producción de l-lisina en el que se utiliza una bacteria alcalifílica |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP2940144A1 (es) |
AR (1) | AR100234A1 (es) |
WO (1) | WO2015165743A1 (es) |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU507634A1 (ru) | 1973-09-24 | 1976-03-25 | Институт Микробиологии Имени А.Кирхенштейна Ан Латвийской Сср | Способ получени -лизина |
JPS559783A (en) | 1978-07-10 | 1980-01-23 | Ajinomoto Co Inc | Preparation of l-lysine by fermentation |
US5250434A (en) | 1987-03-27 | 1993-10-05 | Ajinomoto Co., Inc. | Microorganisms for production of glutamic acid |
GB2223754B (en) | 1988-09-12 | 1992-07-22 | Degussa | Dna encoding phosphoenolpyruvate carboxylase |
DE3943117A1 (de) | 1989-12-27 | 1991-07-04 | Forschungszentrum Juelich Gmbh | Verfahren zur fermentativen herstellung von aminosaeure, insbesondere l-lysin, dafuer geeignete mikroorganismen und rekombinante dna |
JP2990735B2 (ja) | 1990-04-20 | 1999-12-13 | 味の素株式会社 | L―リジンの発酵的製造法 |
JP3023615B2 (ja) | 1990-08-30 | 2000-03-21 | 協和醗酵工業株式会社 | 発酵法によるl―トリプトファンの製造法 |
DE4100920A1 (de) | 1991-01-15 | 1992-07-16 | Degussa | Wirkstoffzubereitung zur oralen verabreichung an wiederkaeuer |
FR2679569B1 (fr) | 1991-07-26 | 1995-05-19 | Eurolysine | Procede de separation de la lysine sous la forme de solutions aqueuses et utilisation de ces solutions pour l'alimentation animale. |
DE4130867A1 (de) | 1991-09-17 | 1993-03-18 | Degussa | Verfahren zur fermentativen herstellung von aminosaeuren |
DE4130868C2 (de) | 1991-09-17 | 1994-10-13 | Degussa | Tierfuttermittelsupplement auf der Basis einer Aminosäure und Verfahren zu dessen Herstellung |
JP3473042B2 (ja) | 1992-04-28 | 2003-12-02 | 味の素株式会社 | 変異型アスパルトキナーゼ遺伝子 |
JPH06261766A (ja) | 1993-03-16 | 1994-09-20 | Mitsubishi Petrochem Co Ltd | フィードバックインヒビションの解除されたアスパルトキナーゼをコードする遺伝子dna及びその利用 |
AU706285B2 (en) | 1995-05-16 | 1999-06-10 | Ajinomoto Co., Inc. | Feed additive |
DE19547361A1 (de) | 1995-12-19 | 1997-06-26 | Degussa | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation |
US5990350A (en) | 1997-12-16 | 1999-11-23 | Archer Midland Company | Process for making granular L-lysine |
MXPA01010413A (es) | 1999-04-19 | 2002-11-29 | Kyowa Hakko Kogyo Kk | Aspartoquinasa desensibilizada novedosa. |
CN1236690C (zh) | 1999-06-23 | 2006-01-18 | 德古萨股份公司 | 含有赖氨酸的含水动物饲料添加剂及其生产方法 |
JP2001120270A (ja) * | 1999-11-01 | 2001-05-08 | Ajinomoto Co Inc | 高温耐性コリネ型細菌の耐熱性リジン生合成系酵素遺伝子 |
JP4623825B2 (ja) | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
US6927046B1 (en) | 1999-12-30 | 2005-08-09 | Archer-Daniels-Midland Company | Increased lysine production by gene amplification using coryneform bacteria |
US6783967B2 (en) | 2001-02-16 | 2004-08-31 | Degussa Ag | Nucleotide sequences which code for the rpoB gene |
CN101126075B (zh) | 2001-08-06 | 2012-05-09 | 赢创德固赛有限公司 | 生产化合物ⅱ的棒状细菌 |
WO2003040373A2 (en) | 2001-08-06 | 2003-05-15 | Degussa Ag | Production of l-lysine by genetically modified corynebacterium glutamicum strains |
US6844176B1 (en) | 2001-10-16 | 2005-01-18 | Degussa Ag | Alleles of the lysC gene from corynebacteria |
JP2003219807A (ja) | 2002-01-25 | 2003-08-05 | Ajinomoto Co Inc | L−リジンを主成分とする造粒乾燥物 |
US20040115304A1 (en) | 2002-12-16 | 2004-06-17 | Frank Dubner | Feesdstuffs additives containing L-lysine with improved abrasion resistance, and process for their production |
WO2005021772A1 (en) | 2003-08-29 | 2005-03-10 | Degussa Ag | Process for the preparation of l-lysine |
KR101052573B1 (ko) | 2004-04-02 | 2011-07-29 | 씨제이제일제당 (주) | 균일한 함량을 갖는 과립형 동물 사료 첨가제를 제조하는 방법 및 그에 의하여 제조되는 과립형 동물 사료 첨가제 |
DE102005032426A1 (de) | 2004-12-18 | 2006-06-22 | Degussa Ag | Allele des gnd-Gens aus coryneformen Bakterien |
DE102005032429A1 (de) | 2005-01-19 | 2006-07-20 | Degussa Ag | Allele des mqo-Gens aus coryneformen Bakterien |
DE102005013676A1 (de) | 2005-03-24 | 2006-09-28 | Degussa Ag | Allele des zwf-Gens aus coryneformen Bakterien |
DE102005023829A1 (de) | 2005-05-24 | 2006-11-30 | Degussa Ag | Allele des opcA-Gens aus coryneformen Bakterien |
DE102006016158A1 (de) | 2005-10-08 | 2007-04-12 | Degussa Ag | L-Lysin enthaltende Futtermitteladditive |
DE102006026328A1 (de) * | 2006-06-02 | 2008-01-03 | Evonik Degussa Gmbh | Verfahren zur Herstellung eines L-Lysin enthaltenden Futtermitteladditivs |
EP2374873A1 (en) * | 2010-04-08 | 2011-10-12 | Technische Universität Hamburg-Harburg | Modified aspartate kinase from corynebacterium and its application for amino acid production |
-
2014
- 2014-04-30 EP EP14166666.9A patent/EP2940144A1/de not_active Withdrawn
-
2015
- 2015-04-16 WO PCT/EP2015/058299 patent/WO2015165743A1/de active Application Filing
- 2015-04-29 AR ARP150101300A patent/AR100234A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
WO2015165743A1 (de) | 2015-11-05 |
EP2940144A1 (de) | 2015-11-04 |
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FB | Suspension of granting procedure |