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Application filed by Genentech IncfiledCriticalGenentech Inc
Publication of AR096626A1publicationCriticalpatent/AR096626A1/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Peptides Or Proteins
(AREA)
Abstract
La solicitud proporciona conjugados anticuerpo-fármaco que comprenden un anticuerpo conjugado a un resto de fármaco dimérico de 1-(clorometil)-2,3-dihidro-1H-benzo[e]indol (CBI) mediante un ligante, y método para utilizar los conjugados anticuerpo-fármaco.The application provides antibody-drug conjugates comprising an antibody conjugated to a dimeric drug moiety of 1- (chloromethyl) -2,3-dihydro-1H-benzo [e] indole (CBI) by a binder, and method of using the antibody-drug conjugates.
ARP140102283A2013-08-122014-06-16
ANTIBODY-DRUG CONJUGATE COMPOUNDS 1- (CHLOROME) -2,3-DIHIDRO-1H-BENZO [E] INDOL, AND METHODS OF USE AND TREATMENT
AR096626A1
(en)
amatoxine conjugate and its use, pharmaceutical composition and its use, amatoxine conjugation molecule, method for the synthesis of an amatoxine conjugate.
Pharmaceutical dosage form comprising 6-fluoro - (n-methyl-or n, n-dimethyl) -4-phenyl -4,9-dihydro-3h-spiro - (cyclohexan-1,1-pyran (3,4, b) indole) -4-amine, useful as an analgesic